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5-Fluorouridine

Cat. No. M21143

All AbMole products are for research use only, cannot be used for human consumption.

5-Fluorouridine Structure
Size Price Availability Quantity
50mg USD 30  USD30 In stock
100mg USD 50  USD50 In stock
200mg USD 65  USD65 In stock
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Quality Control & Documentation
Biological Activity

5-Fluorouridine is a metabolite of 5-fluorouracil, a potent inhibitor of nuclease autocleavage. 5-Fluorouridine binds to total and poly A RNA and has antiproliferative activity. 5-Fluorouridine induces apoptosis (cell death).

Chemical Information
Molecular Weight 262.19
Formula C9H11FN2O6
CAS Number 316-46-1
Solubility (25°C) DMSO ≥ 60 mg/mL
Storage 2-8°C, dry, sealed
References

[1] Mireia Palomar-Siles, et al. Cell Death Dis. Translational readthrough of nonsense mutant TP53 by mRNA incorporation of 5-Fluorouridine

[2] Pavel Škvra, et al. J Sep Sci. Determination of 5-fluorocytosine, 5-fluorouracil, and 5-fluorouridine in hospital wastewater by liquid chromatography-mass spectrometry

[3] Magdalena Slusarczyk, et al. Bioorg Med Chem. Synthesis and biological evaluation of 6-substituted-5-fluorouridine ProTides

[4] Motohiro Tsuzuki, et al. Intern Med. Chronic myeloid leukemia following chemotherapy with 5'-deoxy-5-fluorouridine for gastric cancer

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Keywords: 5-Fluorouridine supplier, DNA/RNA Synthesis, inhibitors, activators

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