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Uridine 5'-diphosphoglucose disodium salt is an agonist of the P2Y14 receptor, with EC50 of 0.35 μM. Uridine 5′-diphosphoglucose disodium salt (UDP-Glucose sodium salt) can also bind to and activate GPR17, inducing oligodendrocyte differentiation at a maximal concentration of 100 μM. Uridine 5'-diphosphoglucose disodium salt is the precursor of glucose-containing oligosaccharides, polysaccharides, glycoproteins, and glycolipids in animal tissues and in some microorganisms.
Neuropharmacology. 2025 Oct 14; .
UDPG/P2Y14-STAT1 axis mediates LPS-induced reactive astrogliosis
Uridine 5'-diphosphoglucose disodium salt purchased from AbMole
| Molecular Weight | 610.27 |
| Formula | C15H22N2Na2O17P2 |
| CAS Number | 28053-08-9 |
| Solubility (25°C) | Water ≥ 100 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
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