Free shipping on all orders over $ 500

P2 Receptor Purinergic2 receptors

Inhibitors

Cat.No.  Name Information
M5986 Suramin sodium salt Suramin Sodium Salt (Suramin hexasodium salt) is a reversible inhibitor of competitive protein tyrosine phosphatases (PTPases).
M21206 ACT-246475 (Selatogrel) ACT-246475 is a new reversible, selective, and potent antagonist of the platelet P2Y12 receptor.
M21197 Brilliant Blue G Brilliant Blue G (BBG) is a potent non-competitive antagonist of P2X7 receptor with IC50 of 10.1 nM and 265 nM for rat P2X7 and human P2X7, respectively. Brilliant Blue G is also a dye which is commonly used in laboratories to stain or quantify proteins.
M14247 PPADS tetrasodium PPADS tetrasodiuma is a non-selective P2X receptor antagonist.
M14246 AZD9056 hydrochloride AZD9056 hydrochloride is a selective orally active inhibitor of P2X7 which plays a significant role in inflammation and pain-causing diseases.
M14245 A-317491 sodium salt hydrate A-317491 sodium salt hydrate is a potent, selective and non-nucleotide antagonist of P2X3 and P2X2/3 receptors, with Kis of 22, 22, 9, and 92 nM for hP2X3, rP2X3, hP2X2/3, and rP2X2/3, respectively.
M10442 Minodronic acid Minodronic acid (YM-529) is an antagonist of purinergic P2X2/3 receptors, Minodronic acid (YM-529) is also a third-generation bisphosphonate that directly and indirectly prevents proliferation, induces apoptosis, and inhibits metastasis of various types of cancer cells.
M9819 BAY-1797 BAY-1797 is a potent and selective, orally active P2X4 antagonist, with IC50 value of 211 nM for human P2X4.
M9740 Aurintricarboxylic acid Aurintricarboxylic acid is a nanomolar-potency, allosteric antagonist with selectivity towards αβ-methylene-ATP-sensitive P2X1Rs and P2X3Rs, with IC50 values of 8.6 nM and 72.9 nM for rP2X1R and rP2X3R, respectively.
M9182 Gefapixant Gefapixant, also known as AF-219 or MK-7264, is a P2X3 receptor antagonist.
M6374 A 804598 A 804598 is a potent and selective P2X7 antagonist.
M6347 5-BDBD 5-BDBD is a potent P2X4 receptor antagonist.
M5986 Suramin sodium salt Suramin Sodium Salt (Suramin hexasodium salt) is a reversible inhibitor of competitive protein tyrosine phosphatases (PTPases).
M5023 Clopidogrel hydrogen sulfate S-(+)-Clopidogrel Hydrogen Sulfate is the S enantiomer of clopidogrel and a P2Y12 receptor inhibitor.
M3280 Clopidogrel Clopidogrel (Plavix) is an oral, thienopyridine class antiplatelet agent used to inhibit blood clots in coronary artery disease, peripheral vascular disease, and cerebrovascular disease.
M3233 GW791343 trihydrochloride GW791343 trihydrochloride is ahydrochloride salt form of GW791343, which is a non-competitive allosteric modulator of human P2X7 receptor inhibitor with pIC50 of 7.
M3185 Ticlopidine hydrochloride Ticlopidine hydrochloride is a selective P2Y12 receptor antagonist.
M3069 Ticagrelor Ticagrelor is the first reversibly binding oral P2Y12 receptor antagonist with Ki of 2 nM respectively.
M2954 PPADS Tetrasodium Salt PPADS tetrasodium salt is a non-selective P2 purinergic antagonist blocking recombinant P2X1, P2X2, P2X3, P2X5 with IC50 of 1-2.6 μM, native P2Y2-like with IC50 of ~ 0.9 mM, and recombinant P2Y4 receptors with IC50 of ~ 15 mM
M2869 MRS 2578 MRS2578 is a potent P2Y6 receptor antagonist with IC50 of 37 nM, exhibits insignificant activity at P2Y1, P2Y2, P2Y4,and P2Y11 receptors.
M2234 Prasugrel Prasugrel is a platelet inhibitor irreversibly binding to P2Y12 receptors.



Contact Us

Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2020 AbMole BioScience. All Rights Reserved.