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P2 Receptor Purinergic2 receptors

Cat.No.  Name Information
M5986 Suramin sodium salt Suramin Sodium Salt (Suramin hexasodium salt) is a reversible inhibitor of competitive protein tyrosine phosphatases (PTPases).
M55230 UDP-Galactose disodium UDP-Galactose disodium is a monosaccharide and a P2Y14 receptor agonist with an EC50 value of 0.67 μM.
M25420 Camlipixant Camlipixant (BLU-5937) a potent, selective, non-competitive and orally active P2X3 homotrimeric receptor antagonist with an IC50 of 25 nM against hP2X3 homotrimeric.
M14245 A-317491 sodium salt hydrate A-317491 sodium salt hydrate is a potent, selective and non-nucleotide antagonist of P2X3 and P2X2/3 receptors, with Kis of 22, 22, 9, and 92 nM for hP2X3, rP2X3, hP2X2/3, and rP2X2/3, respectively.
M14041 Diquafosol tetrasodium Diquafosol tetrasodium is a P2Y2 receptor agonist that stimulates fluid and mucin secretion on the ocular surface, as a topical treatment of dry eye disease.
M11483 A 438079 A 438079 is A potent, selective P2X7 receptor antagonist with A pIC50 of 6.9.
M11482 A 438079 hydrochloride A 438079 Hydrochloride is A potent, selective P2X7 receptor antagonist with A pIC50 of 6.9.
M11206 A-317491 A-317491 is a potent, selective and non-nucleotide antagonist of P2X3 and P2X2/3 receptors, with Kis of 22, 22, 9, and 92 nM for hP2X3, rP2X3, hP2X2/3, and rP2X2/3, respectively. A-317491 is highly selective for other P2 receptors and neurotransmitter receptors, ion channels, and enzymes (IC50>10 μM).
M10915 RO3 RO3 is a selective antagonist of homomeric P2X3 and heteromeric P2X2/3 receptor
M10485 Oleoyl-L-α-lysophosphatidic acid sodium salt Oleoyl-L-α-lysophosphatidic acid (LPA) sodium salt is a ligand for P2Y5.
M10442 Minodronic acid Minodronic acid (YM-529) is an antagonist of purinergic P2X2/3 receptors, Minodronic acid (YM-529) is also a third-generation bisphosphonate that directly and indirectly prevents proliferation, induces apoptosis, and inhibits metastasis of various types of cancer cells.
M9819 BAY-1797 BAY-1797 is a potent and selective, orally active P2X4 antagonist, with IC50 value of 211 nM for human P2X4.
M9740 Aurintricarboxylic acid Aurintricarboxylic acid is a nanomolar-potency, allosteric antagonist with selectivity towards αβ-methylene-ATP-sensitive P2X1Rs and P2X3Rs, with IC50 values of 8.6 nM and 72.9 nM for rP2X1R and rP2X3R, respectively.
M9182 Gefapixant Gefapixant, also known as AF-219 or MK-7264, is a P2X3 receptor antagonist.
M8762 Cangrelor tetrasodium salt Canrelor is an adenosine triphosphate analog as well as a potent and selective platelet P2Y12 antagonist and a non-specific GPR17 antagonist.
M7668 BMS-646786 BMS-646786 is a potent and specific inhibitor of P2Y1 purinergic receptor that inhibits ADP-mediated platelet aggregation in human blood samples.
M7452 UDP disodium salt UDP disodium salt is a endogenous ligand; competitive antagonist at P2Y 14 receptors.
M6848 JNJ 47965567 JNJ 47965567 is a potent and selective P2X7 antagonist; brain penetrant.
M6480 AZD 1283 AZD 1283 is a high affinity P2Y 12 antagonist.
M6374 A-804598 A-804598 is a CNS penetrant, competitive and selective P2X7 receptor antagonist with IC50s of 9 nM, 10 nM and 11 nM for mouse, rat and human P2X7 receptors, respectively.




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