| Cat.No. | Name | Information |
|---|---|---|
| M5986 | Suramin sodium salt | Suramin Sodium Salt (Suramin hexasodium salt) is a reversible inhibitor of competitive protein tyrosine phosphatases (PTPases). |
| M55230 | UDP-Galactose disodium | UDP-Galactose disodium is a monosaccharide and a P2Y14 receptor agonist with an EC50 value of 0.67 μM. |
| M30139 | 2-Methylthioadenosine diphosphate trisodium | 2-Methylthioadenosine diphosphate trisodium is a potent purinergic P2Y receptors agonist, with EC50s of 19, 6.2, and 5 nM for human P2Y13, mouse P2Y13 and human P2Y12, respectively. 2-Methylthioadenosine diphosphate trisodium has pEC50s of 8.29 and 5.75 for human P2Y1 and rat P2Y6, respectively. |
| M28720 | JNJ-54175446 | JNJ-54175446 is a potent and selective brain penetrant P2X7 receptor antagonist, with pIC50s of 8.46 and 8.81 for hP2X7 receptor and rP2X7 receptor, respectively. |
| M25580 | PPTN hydrochloride | PPTN hydrochloride is a potent, high-affinity, competitive and highly selective P2Y14 receptor antagonist with a KB value of 434 pM. |
| M25420 | Camlipixant | Camlipixant (BLU-5937) a potent, selective, non-competitive and orally active P2X3 homotrimeric receptor antagonist with an IC50 of 25 nM against hP2X3 homotrimeric. |
| M14245 | A-317491 sodium salt hydrate | A-317491 sodium salt hydrate is a potent, selective and non-nucleotide antagonist of P2X3 and P2X2/3 receptors, with Kis of 22, 22, 9, and 92 nM for hP2X3, rP2X3, hP2X2/3, and rP2X2/3, respectively. |
| M14041 | Diquafosol tetrasodium | Diquafosol tetrasodium is a P2Y2 receptor agonist that stimulates fluid and mucin secretion on the ocular surface, as a topical treatment of dry eye disease. |
| M11483 | A 438079 | A 438079 is A potent, selective P2X7 receptor antagonist with A pIC50 of 6.9. |
| M11482 | A 438079 hydrochloride | A 438079 Hydrochloride is A potent, selective P2X7 receptor antagonist with A pIC50 of 6.9. |
| M11206 | A-317491 | A-317491 is a potent, selective and non-nucleotide antagonist of P2X3 and P2X2/3 receptors, with Kis of 22, 22, 9, and 92 nM for hP2X3, rP2X3, hP2X2/3, and rP2X2/3, respectively. A-317491 is highly selective for other P2 receptors and neurotransmitter receptors, ion channels, and enzymes (IC50>10 μM). |
| M10915 | RO3 | RO3 is a selective antagonist of homomeric P2X3 and heteromeric P2X2/3 receptor |
| M10485 | Oleoyl-L-α-lysophosphatidic acid sodium salt | Oleoyl-L-α-lysophosphatidic acid (LPA) sodium salt is a ligand for P2Y5. |
| M10442 | Minodronic acid | Minodronic acid (YM-529) is an antagonist of purinergic P2X2/3 receptors, Minodronic acid (YM-529) is also a third-generation bisphosphonate that directly and indirectly prevents proliferation, induces apoptosis, and inhibits metastasis of various types of cancer cells. |
| M10064 | Uridine 5'-diphosphoglucose disodium salt | Uridine 5'-diphosphoglucose disodium salt is an agonist of the P2Y14 receptor, with EC50 of 0.35 μM. Uridine 5′-diphosphoglucose disodium salt (UDP-Glucose sodium salt) can also bind to and activate GPR17, inducing oligodendrocyte differentiation at a maximal concentration of 100 μM. |
| M9819 | BAY-1797 | BAY-1797 is a potent and selective, orally active P2X4 antagonist, with IC50 value of 211 nM for human P2X4. |
| M9740 | Aurintricarboxylic acid | Aurintricarboxylic acid is a nanomolar-potency, allosteric antagonist with selectivity towards αβ-methylene-ATP-sensitive P2X1Rs and P2X3Rs, with IC50 values of 8.6 nM and 72.9 nM for rP2X1R and rP2X3R, respectively. |
| M9182 | Gefapixant | Gefapixant, also known as AF-219 or MK-7264, is a P2X3 receptor antagonist. |
| M8762 | Cangrelor tetrasodium salt | Canrelor is an adenosine triphosphate analog as well as a potent and selective platelet P2Y12 antagonist and a non-specific GPR17 antagonist. |
| M7668 | BMS-646786 | BMS-646786 is a potent and specific inhibitor of P2Y1 purinergic receptor that inhibits ADP-mediated platelet aggregation in human blood samples. |
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