About 30 results found for searched term "TRi-1" (0.055 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M1845 | LY335979 trihydrochloride | P-glycoprotein |
| Zosuquidar trihydrochloride; RS 33295-198 trihydrochloride | ||
| LY335979 (Zosuquidar trihydrochloride) is a selective Pgp (P-glycoprotein) inhibitor with a Ki of 59 nM. *The compound is unstable in solutions, freshly prepared is recommended | ||
| M3222 | Peramivir Trihydrate | Anti-infection |
| BCX-1812 Trihydrate; RWJ-270201 Trihydrate; S-021812 Trihydrate | ||
| Peramivir Trihydrate is a trihydrate of the anti-infection agent peramivir (RWJ-270201,BCX-1812) which is a transition-state analogue and a potent, specific influenza viral neuraminidase inhibitor with an IC50 of median 0.09 nM. | ||
| M3379 | Trifluridine | DNA/RNA Synthesis |
| Trifluridine; FTD; 5-Trifluorothymidine; NSC 529182; NSC 75520 | ||
| Trifluridine (Trifluorothymidine) is an irreversible and orally active thymidylate synthase inhibitor, and thereby suppressing DNA synthesis. Trifluridine is an antiviral molecule used for research of HSV, rhabdovirus and orthopoxvirus infection. | ||
| M3877 | 4-Chloro-3-(trifluoromethyl)-1H-pyrrolo[2,3-b]pyridine | Others |
| 4-Chloro-3-(trifluoromethyl)-1H-pyrrolo[2,3-b]pyridine | ||
| M4914 | Tyloxapol | Animal Modeling |
| Triton WR1339 | ||
| Tyloxapol is a nonionic liquid polymer of the alkyl aryl polyether alcohol type, used as a surfactant to aid liquefaction. | ||
| M6069 | β-Estradiol 17-acetate | Estrogen Receptor |
| 1,3,5(10)-Estratriene-3,17β-diol 17-acetate | ||
| β-Estradiol 17-acetate is a metabolite of estradiol. | ||
| M6389 | 1-Aminobenzotriazole (ABT) | Cytochrome P450 (e.g. CYP17) |
| ABT; 3-Aminobenzotriazole; 1-Benzotriazolylamine; NSC 114498; NSC 656987 | ||
| 1-Aminobenzotriazole (ABT) is a cytochrome P450 inhibitor; inhibits 20-HETE synthesis. | ||
| M6451 | Apigenin | Cytochrome P450 (e.g. CYP17) |
| 4',5,7-Trihydroxyflavone; Apigenine; Apigenol; C.I. Natural Yellow 1 | ||
| Apigenin is a competitive CYP2C9 inhibitor with a Ki of 2 μM. | ||
| M6594 | CHIR 99021 trihydrochloride | GSK-3 |
| Laduviglusib trihydrochloride; CT99021 trihydrochloride | ||
| Laduviglusib (CHIR-99021) trihydrochloride is a potent and selective GSK-3α/β inhibitor with IC50s of 10 nM and 6.7 nM. Laduviglusib trihydrochloride shows >500-fold selectivity for GSK-3 over CDC2, ERK2 and other protein kinases. Laduviglusib trihydrochloride is also a potent Wnt/β-catenin signaling pathway activator. | ||
| M6826 | INCA-6 | NFAT |
| INCA6; Triptycene-1,4-quinone | ||
| INCA-6 is a inhibitor of interaction between calcineurin and its substrate nuclear factor of activated T cells (NFAT). | ||
| M8390 | Nestorone | Progesterone Receptor |
| Elcometrine; Nestorone; ST-1435 | ||
| Nestorone is a potent progesterone receptor agonist with no androgenic, estrogenic, or glucocorticoid-like activities. | ||
| M8479 | Pyr6 | Others |
| N-[4-[3,5-Bis(trifluoromethyl)-1H-pyrazol-1-yl]phenyl]-3-fluoro-4-pyridinecarboxamide | ||
| Pyr6 is a selective inhibitor of calcium release from the endoplasmic reticulum via STIM1/Orai1 mediated, store operated calcium entry (SOCE). | ||
| M9320 | Gastrin-I (human) | Cholecystokinin Receptor |
| Gastrin-1 | ||
| Gastrin-I (human) is the endogenous peptide produced in the stomach, which increases gastric acid secretion via cholecystokinin 2 (CCK2) receptor. | ||
| M9932 | Tris[(1-benzyl-1H-1,2,3-triazol-4-yl)methyl]amine | Others |
| TBTA | ||
| Tris[(1-benzyl-1H-1,2,3-triazol-4-yl)methyl]amine (TBTA) is a ligand that acts as a biochemical tool for the tagging of proteins and enzymes. | ||
| M10247 | Nesiritide acetate | Peptides |
| natriureticpeptide; BNP-32; 124584-08-3 | ||
| Nesiritide acetate is an agonist of natriuretic peptide receptors (NPRs), with Kd values of 7.3 and 13 pM for NPR-A and NPR-C, respectively. | ||
| M10358 | C-Type Natriuretic Peptide (CNP) (1-22), human | Angiotensin Receptor |
| CNP-22, human | ||
| C-Type Natriuretic Peptide (CNP) (1-22), human is the 1-22 fragment of C-Type Natriuretic Peptide. | ||
| M13957 | Carperitide acetate | Endothelin Receptor |
| Atrial Natriuretic Peptide (ANP) (1-28), human, porcine acetate | ||
| Carperitide acetate (Atrial Natriuretic Peptide (ANP) (1-28), human, porcine acetate) is a 28-amino acid hormone, that is normally produced and secreted by the human heart in response to cardiac injury and mechanical stretch. | ||
| M14030 | Matrine | Opioid Receptor |
| Matridin-15-one; Vegard; α-Matrine | ||
| Matrine (Matridin-15-one) is an alkaloid found in plants from the Sophora genus. It has a variety of pharmacological effects, including anti-cancer effects, and action as a kappa opioid receptor and u-receptor agonist. | ||
| M16347 | 6α,16,18-Trihydroxycleroda -3,13-dien-15,16-olide | Diterpenoids |
| 6α,16,18-Trihydroxycleroda -3,13-dien-15,16-olide | ||
| M16350 | 2β,6β,15α-Trihydroxy-ent-kaur-16-ene | Diterpenoids |
| 2β,6β,15α-Trihydroxy-ent-kaur-16-ene | ||
| M16354 | ent-13,16β,17-Trihydroxykauran-19-oic acid | Diterpenoids |
| ent-13,16β,17-Trihydroxykauran-19-oic acid | ||
| M16362 | 18-Norabieta-8,11,13-triene-4,15-diol | Diterpenoids |
| 18-Norabieta-8,11,13-triene-4,15-diol | ||
| M16520 | 2α,7β,13α-Triacetoxy-5α-cinnamoyloxy-9β- hydroxy-2(3→20)abeotaxa-4(20),11-dien-10-one | Diterpenoids |
| 2α,7β,13α-Triacetoxy-5α-cinnamoyloxy-9β- hydroxy-2(3→20)abeotaxa-4(20),11-dien-10-one | ||
| M17060 | 2,4,7-Trihydroxy-9,10-dihydrophenanthrene | Phenols |
| 2,4,7-Trihydroxy-9,10-dihydrophenanthrene | ||
| M17664 | 2α,3α,24-Trihydroxyolean-12-en-28-oic acid | Triterpenoids |
| 2α,3α,24-Trihydroxyolean-12-en-28-oic acid | ||
| M17665 | 3β,7β,25-Trihydroxycucurbita-5,23-dien-19-al | Triterpenoids |
| 3β,7β,25-Trihydroxycucurbita-5,23-dien-19-al | ||
| M17666 | 2α,3α,24-Trihydroxyurs-12-en-28-oic acid | Triterpenoids |
| 2α,3α,24-Trihydroxyurs-12-en-28-oic acid | ||
| M17923 | Cyclohexanecarboxylic acid, 3-[[ (2E)-3-[4-(D-glucopyranosyloxy)-3-hydroxyphenyl]-1-oxo-2-propen-1-yl]oxy]-1,4,5-trihydroxy-, (1S,3R,4R,5R)- | Others |
| Cyclohexanecarboxylic acid, 3-[[（2E）-3-[4-（D-glucopyranosyloxy）-3-hydroxyphenyl]-1-oxo-2-propen-1-yl]oxy]-1,4,5-trihydroxy-, （1S,3R,4R,5R）- | ||
| M17929 | 1,3,6-trihydroxy-2-methyl-9,10-anthraquinone-3-O-α-L-rhamnopyranosyl-(1->2)-β-D-glucopyranoside | Others |
| 1,3,6-trihydroxy-2-methyl-9,10-anthraquinone-3-O-α-L-rhamnopyranosyl-（1->2）-β-D-glucopyranoside | ||
| M17930 | 2,4,6-trichlorol-3-methyl-5-methoxyphenol-1-O-β-D-glucopyranosyl-(1→6)-β-D-glucopyranoside | Others |
| 2,4,6-trichlorol-3-methyl-5-methoxyphenol-1-O-β-D-glucopyranosyl-（1→6）-β-D-glucopyranoside | ||
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