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Nestorone is a potent progesterone receptor agonist with no androgenic, estrogenic, or glucocorticoid-like activities. Nestorone has been used as a female contraceptive, and recent studies inidicate that it may be useful as a male contraceptive as well. It has also been shown to have neurogenic and neuroprotective activity.
| Molecular Weight | 370.48 |
| Formula | C23H30O4 |
| CAS Number | 7759-35-5 |
| Form | Solid |
| Solubility (25°C) | DMSO: 5 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[5] Regine Sitruk-Ware, et al. Nestorone: clinical applications for contraception and HRT
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