About 30 results found for searched term "Smo" (0.049 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M1713 | GDC-0449 (Vismodegib) | Smo |
| Vismodegib, HhAntag691 | ||
| GDC-0449 (Vismodegib) is a potent and specific hedgehog pathway inhibitor with IC50 values of 1.4 and 3.0μM for inhibition of ABCG2 and Pgp respectively. | ||
| M2338 | LDE225 | Hedgehog |
| Sonidegib; NVP-LDE225; Erismodegib | ||
| LDE225 (NVP-LDE225; Sonidegib) is a Hedgehog signaling pathway inhibitor (via smoothened antagonism) with IC50 of 1.3 nM (mouse) and 2.5 nM (human), respectively. | ||
| M2682 | Esmolol hydrochloride | Adrenergic Receptor |
| Esmolol is a cardioselective beta adrenergic receptor blocker, used to control rapid heartbeats or abnormal heart rhythms. | ||
| M4109 | Alisol-B-23-acetate | Apoptosis |
| 23-Acetylalismol B; 23-O-Acetylalisol B; Alisol B monoacetate | ||
| Alisol B 23-acetate (23-acetylalismol B) is a triterpenoid compound that promotes regeneration of damaged liver by activating farnesol receptors. | ||
| M4114 | Alismoxide | Others |
| (+)-Alismoxide | ||
| Alismoxide is a natural compound. | ||
| M4237 | Apigenin-7-glucoside | ROS |
| Apigenin-7-O-β-D-glucopyranoside; Apigetrin; Cosmosiin | ||
| Apigenin-7-glucoside (Apigenin-7-O-β -D-Glucopyranoside), ROS scaver, has anti-proliferation and antioxidant activities. | ||
| M4725 | β-Eudesmol | Others |
| Eudesmol is a sesquiterpenoid produced by Streptomyces Tendae. | ||
| M4841 | LDE225 (Sonidegib) diphosphate | Smo |
| NVP-LDE225; Erismodegib; Sonidegib diphosphate | ||
| LDE225 Diphosphate (Sonidegib diphosphate) is a Smoothened (Smo) antagonist, inhibiting Hedgehog (Hh) signaling with IC50 of 1.3 nM (mouse) and 2.5 nM (human), respectively. | ||
| M4865 | Smoothened Agonist (SAG) HCl | Smo |
| SAG.HCl; 912545-86-9 | ||
| Smoothened Agonist (SAG) HCl is a cell-permeable Smoothened (Smo) agonist with EC50 of 3 nM in Shh-LIGHT2 cells. | ||
| M9435 | Methyl jasmonate | Plant growth regulators |
| Meja | ||
| Methyl jasmonate is a plant growth regulator isolated from Jasmine grandiflora. | ||
| M9862 | Desmopressin diacetate | Others |
| DDAVP; CAS# 16679-58-6 | ||
| Desmopressin diacetate is a selective and potent vasopressor agent that stabilizes the cardiocirculatory function in normal human as well as in patients suffering from catecholamine-resistant vasodilatory shock. | ||
| M11457 | Desmopressin Acetate | Vasopressin Receptor |
| Desmopressin is a synthetic octapeptide that is an analogue of the human hormone arginine vasopressin and has antidiuretic and procoagulant effects. | ||
| M14364 | Desmosterol | Metabolite/Endogenous Metabolite |
| (EPB (Desmosterol) | ||
| Desmosterol is a molecule similar to cholesterol. Desmosterol is the immediate precursor of cholesterol in the Bloch pathway of cholesterol biosynthesis. Desmosterol, as an endogenous metabolite, used to study cholesterol metabolism. | ||
| M16297 | Thamnosmonin | Coumarins |
| Thamnosmonin | ||
| M16886 | Jasmoside | Iridoids |
| Jasmoside | ||
| M17487 | 1β-Hydroxy-β-eudesmol | Sesquiterpenoids |
| 1β-Hydroxy-β-eudesmol | ||
| M20459 | Methyl Dihydrojasmonate | Others |
| Hedione, Kharismal | ||
| Methyl dihydrojasmonate is a flavouring ingredien with the smell vaguely similar to jasmin. | ||
| M20537 | Esmolol | Adrenergic Receptor |
| Esmolol is a cardioselective beta1 receptor blocker with rapid onset, a very short duration of action, and no significant intrinsic sympathomimetic or membrane stabilising activity at therapeutic dosages. | ||
| M31085 | (±)-Jasmonic acid | Plant growth regulators |
| JA | ||
| (±)-Jasmonic acid is a plant growth regulator and a natural oxidizing monocarboxylic acid that reduces chlorophyll levels in green and yellowing barley leaf segments and inhibits elongation of rice seedlings. | ||
| M28353 | 12-Hydroxyjasmonic acid | Others |
| (-)-12-Hydroxyjasmonic acid | ||
| 12-Hydroxyjasmonic acidis is a COI1-JAZ-independent activator of leaf-closing movement in Samanea saman. | ||
| M31087 | (±)-Dihydrojasmonic Acid | Plant growth regulators |
| 2HJA | ||
| (±)-Dihydrojasmonic Acid is a natural product found in wild pea plants. | ||
| M31091 | Jasmonyl isoleucine | Plant growth regulators |
| JA-Ile | ||
| Jasmonyl isoleucine is an amino acid adduct that also acts as an important signaling compound in stress defense and development of plants. | ||
| M39712 | (11S)-(-)-Hydroxyjasmonic acid | Others |
| (11S)-(-)-Hydroxyjasmonic acid is a hydroxylated cyclopentane fatty acid of the jasmonic acid type that can be found in the culture filtrate of the fungus Botryodiplodia theobromae<. | ||
| M42015 | Alismol | NO Synthase |
| Alismol is a natural sesquiterpene. | ||
| M44794 | beta-Eudesmol | TRP Channel |
| Beta-Eudesmol is a natural oxygenated sesquiterpene, activates hTRPA1, with an EC50 of 32.5 μM. Beta-Eudesmol increases appetite through TRPA1. | ||
| M44812 | cis-Jasmone | Others |
| Cis-Jasmone is a plant-derived natural product. | ||
| M50259 | Sporidesmolide V | Others |
| Sporidesmolide V is a cyclodepsipeptide compound isolated from the cultures of Pithornyces chartarum. | ||
| M53320 | Myosin Light Chain Kinase Substrate (smooth muscle) | Myosin |
| Myosin Light Chain Kinase Substrate (smooth muscle) is a smooth muscle myosin light chain kinase (MLCK) synthetic peptide substrate. | ||
| M55630 | Recombinant Human Desmoplakin/DSP Protein (E. coli, N-His) | Cytokines and Growth Factors |
| 250/210 kDa paraneoplastic pemphigus antigen; DCWHKTA; DP | ||
| DSP proteins are major components of desmosomes and are critical for the structural integrity of various tissues. In cardiomyocytes, DSP regulates profibrotic gene expression through MAPK14/p38 MAPK activation and increased TGFB1 protein. | ||
| M57703 | Isodesmosine | Others |
| Isodesmosine | ||
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