Free shipping on all orders over $ 500

β-Eudesmol

Cat. No. M4725
β-Eudesmol Structure
Size Price Availability Quantity
20mg USD 450  USD450 In stock
Free Delivery on orders over USD 500 Bulk Inquiry?

Quality Control & Documentation
Biological Activity

Eudesmol is a sesquiterpenoid produced by Streptomyces Tendae.

Chemical Information
Molecular Weight 222.37
Formula C15H26O
CAS Number 51317-08-9
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Conversion of different model animals based on BSA (PMID: 27057123)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.

References

[1] Bishwanath Acharya, et al. Therapeutic potential and pharmacological activities of β-eudesmol

[2] Gyem Tshering, et al. Embryotoxicity evaluation of atractylodin and β-eudesmol using the zebrafish model

[3] Takahiro Tsusaka, et al. Evaluation of heritability of β-eudesmol/hinesol content ratio in Atractylodes lancea De Candolle

[4] Sun-Young Nam, et al. Βeta-eudesmol reduces stem cell factor-induced mast cell migration

[5] Na-Ra Han, et al. β-eudesmol suppresses allergic reactions via inhibiting mast cell degranulation

Related Products
Efanesoctocog alfa

Efanesoctocog alfa is a novel fusion protein consisting of a single-chain factor VIII (FVIII) with a deletion in the B structural domain linked to the D'D3 structural domain of vascular hemophilic factor (VWF). It can be used for research related to hemophilia A.

FR054

FR054 is a hexosamine biosynthesis pathway enzyme PGM3 inhibitor with anticancer activity and can be used in studies related to breast cancer.

Benproperine phosphate

Benproperine phosphate is an orally active, potent inhibitor of actin-associated protein 2/3 complex subunit 2 (ARPC2) that attenuates the rate of actin polymerization by impairing the function of Arp2/3.Benproperine phosphate inhibits cancer cell migration and tumor metastasis and has been used in studies related to cough. Benproperine phosphate inhibits cancer cell migration and tumor metastasis and can be used in cough-related studies.

Zilebesiran

Zilebesiran is a small interfering RNA covalently linked to the N-acetylgalactosamine ligand that binds with high affinity to the hepatic asialoglycoprotein receptor.Zilebesiran specifically reduces hepatic angiotensinogen messenger RNA, thereby decreasing angiotensinogen synthesis.

Anselamimab

Anselamimab is a human IgG1κ anti-amyloidogenic fibrillar antibody targeting serum amyloid A1 (SAA1) for studies related to AL-type amyloidosis.

  Catalog
Abmole Inhibitor Catalog




Keywords: β-Eudesmol supplier, inhibitors, activators


Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2023 AbMole BioScience. All Rights Reserved.