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(±)-Dihydrojasmonic Acid

Cat. No. M31087
(±)-Dihydrojasmonic Acid Structure
Synonym:

2HJA

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Biological Activity

(±)-Dihydrojasmonic Acid is a natural product found in wild pea plants.

Chemical Information
Molecular Weight 212.29
Formula C12H20O3
CAS Number 76968-33-7
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Conversion of different model animals based on BSA (PMID: 27057123)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.

References

[1] Chimaobi J Ononamadu, et al. BioTechnologia (Pozn). Molecular docking and prediction of ADME/drug-likeness properties of potentially active antidiabetic compounds isolated from aqueous-methanol extracts of Gymnema sylvestre and Combretum micranthum

[2] Kolby J Jardine, et al. Plants (Basel). Light-Dependence of Formate (C1) and Acetate (C2) Transport and Oxidation in Poplar Trees

[3] Hassan H A Mostafa, et al. Sci Rep. Effects of genotypes and explants on garlic callus production and endogenous hormones

[4] Yue Ruan, et al. Food Funct. Changes of urine metabolites in response to n-3 fatty acid supplements and their correlation with metabolic risk factors in patients with type 2 diabetes

[5] Nigel E Gapper, et al. Physiol Plant. Novel jasmonate amino acid conjugates in Asparagus officinalis during harvest-induced and natural foliar senescence

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Keywords: (±)-Dihydrojasmonic Acid, 2HJA supplier, Plant growth regulators, inhibitors, activators


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