About 30 results found for searched term "ROS" (0.004 seconds)
Cat.No. | Name | Target |
---|---|---|
M1894 | Rosiglitazone | PPAR |
BRL 49653 | ||
Rosiglitazone (BRL 49653) is an orally active selective PPARγ agonist (EC50=60 nM, Kd=40 nM). Rosiglitazone is an TRPC5 activator (EC50=30 μM) and TRPM3 inhibitor. | ||
M1974 | Roscovitine (Seliciclib) | CDK |
Seliciclib, CYC202 | ||
Roscovitine is a potent and selective inhibitor of the cyclin-dependent kinases cdc2, cdk2 and cdk5. | ||
M2038 | Rosiglitazone maleate | PPAR |
Avandia | ||
Rosiglitazone maleate (Avandia) is a potent and selective PPARγ ligand that binds to the PPARγ ligand-binding domain with a Kd value of 43 nM. | ||
M2066 | Staurosporine | PKC |
AM-2282; STS; CGP 41251 | ||
Staurosporine (AM-2282) is a potent ATP-competitive kinase inhibitor with IC50 of 0.7, 7, 8.5, 6, 20 nM for PKC, PKA,PKG, p60v-src tyrosine protein kinase, CaM kinase II, respectively. | ||
M2283 | Rosuvastatin calcium | HMG-CoA Reductase |
Crestor; ZD 4522 Calcium | ||
Rosuvastatin (Crestor) is a member of statins and used to treat high cholesterol and related conditions. | ||
M2315 | Necrostatin-1 | RIPK |
Nec-1 | ||
Necrostatin-1 (NEC-1) is a potent inhibitor of necroptosis, with an EC50 of 490 nM in Jurkat cells. Necrostin-1 is the first identified RIPK1 inhibitor, EC50=182 nM, that reduces inflammation and inhibits colitis associated tumorigenesis. Necrostatin-1 (Nec-1) is also an inhibitor of IDO. | ||
M2670 | Epiandrosterone | Androgen Receptor |
3β-androsterone, EpiA | ||
Epiandrosterone is a steroid hormone with weak androgenic activity, is a natural metabolite of DHEA. | ||
M2674 | Eprosartan Mesylate | Angiotensin Receptor |
Futuran; Navixen | ||
Eprosartan is a nonpeptide angiotensin II receptor antagonist, [3H]-eprosartan binds to the AT1 receptor with KD of 0.83 nM in rat vascular smooth muscle cells. | ||
M2698 | Ferrostatin-1 | Ferroptosis |
Fer-1 | ||
Ferrostatin-1 (Fer-1) is a potent and selective inhibitor of ferroptosis with EC50 of 60 nM. | ||
M3035 | Sucralose | Metabolite/Endogenous Metabolite |
E955; Trichlorosucrose | ||
Sucralose is an artificial and noncaloric sweetener, not broken down by the body. | ||
M3331 | Trospium chloride | AChR/AChE |
Trospium chloride is an orally active, competitive muscarinic cholinergic receptors (mAChRs) antagonist. Trospium chloride binds to muscarinic receptors M1, M2 and M3 with high affinity, but not nicotinic, cholinergic receptors. | ||
M3409 | Formestane | Others |
4-hydroxyandrostenedione | ||
Formestane is a second generation selective aromatase inhibitor with an IC50 of 80 nM. | ||
M3436 | Furosemide | Sodium Channel |
Furosemide is a tabular diuretic used in studies of congestive heart failure and edema. | ||
M3459 | Lubiprostone | Others |
CAS# 333963-40-9 | ||
Lubiprostone is a gastrointestinal agent used for the treatment of idiopathic chronic constipation. | ||
M3696 | Rostafuroxin | ATPase |
PST 2238 | ||
Rostafuroxin, a novel antihypertensive compound, acts as a selective inhibitor of srC-SH2 interaction with Na, K-ATPase activated by mutated adducin and Wabin in vivo. | ||
M3881 | Tafluprost | Prostaglandin Receptor |
Taflotan, Zioptan, AFP-168, MK2452 | ||
Tafluprost is a fluorinated analog of prostaglandin F2-alpha and a PGF2alpha agonist that may be used in glaucoma-related studies. | ||
M3899 | Salidroside | mTOR |
Rhodioloside | ||
Salidroside is a phenylpropanoid extracted from Rhodiola rosea that exhibits a protective effect against iron death by activating AMPK. It is also a prolyl endopeptidase inhibitor. | ||
M3910 | Sweroside | Others |
Sweroside is a bioactive herbal ingredient isolated from Fructus Corni, which has been widely used for the treatment of osteoporosis in traditional Chinese medicine (TCM). | ||
M3926 | Cynaroside | Akt |
Luteolin-7-O-D-glucopyranoside | ||
Cynaroside is a flavone, it is a 7-O-glucoside of luteolin that exhibits anti-oxidative capabilities. Cynaroside is also a potent influenza RNA-dependent RNA polymerase inhibitor with an IC50 of 32 nM. | ||
M4004 | Hyperoside | Apoptosis |
Hyperoside is a potent natural activator of Nur77 receptor, which can be potentially used for the research of occlusive vascular diseases. Hyperoside is also a NF-κB inhibitor. Hyperoside shows anti-tumor, antifungal, anti-inflammatory, anti-viral, and anti-oxidative activities, and can induce apoptosis. | ||
M4050 | Mogroside-V | ROS |
Mogroside V is a triterpenoid glycoside, which is a non-saccharide sweetener. Mogroside V is nearly 300 times sweeter than sucrose. Mogrosides has antioxidant, anti-diabetic and anti-cancer activities. | ||
M4051 | Mogroside-IVa | Others |
Mogroside IV-A is A triterpenoid glycoside that can be isolated from the extract of momordica grosvenorii fruit. Mogroside IV-A is A non-carbohydrate sweetener. Mogroside is sweeter than sucrose. Mogroside has antioxidant, anti-diabetic and anticancer activities. | ||
M4052 | Isomogroside-V | Others |
Isomogroside V is a new sweetener extracted from momordica grosvenori fruit. | ||
M4053 | Mogroside-IIIA1 | Others |
Mogroside III-A1 is a triterpenoid glycoside, which is a non-saccharide sweetener. Mogroside is sweeter than sucrose. Mogroside has antioxidant, anti-diabetic and anticancer activities. | ||
M4054 | Mogroside-IIA2 | Others |
Mogroside II-A2 is a triterpenoid glycoside, which is a non-saccharide sweetener. Mogroside is sweeter than sucrose. Mogroside has antioxidant, anti-diabetic and anticancer activities. | ||
M4055 | Mogroside-IIIe | Others |
Mogroside III-E is a cucurbitane type compound isolated from momordica grosveneri, which can inhibit the release of NO and has anti-pulmonary fibrosis effect. | ||
M4056 | Grosvenorine | Antibiotic |
Grosvenorine is the main flavonoid in momordica Grosvenorine. Grosvenorine has good antibacterial and antioxidant activity. | ||
M4057 | Mogroside-IV | Others |
Mogroside IV is a triterpenoid glycoside that can be isolated from momordica fruit extract. Mogroside IV is a non-carbohydrate sweetener. Mogroside is sweeter than sucrose. Mogroside has antioxidant, anti-diabetic and anticancer activities. | ||
M4058 | 11-oxo-mogroside-V | ROS |
11-Oxo-Mogroside V is a natural sweetener with strong antioxidant activity. 11-OXo-Mogroside V had a significant inhibitory effect on reactive oxygen species, and the EC50 of O2-, H2O2 and *OH were 4.79, 16.52 and 146.17 μg/mL, respectively. | ||
M4060 | Mogroside-VI | Others |
Mogroside-VI |
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