All AbMole products are for research use only, cannot be used for human consumption.
Rosuvastatin (Crestor) is a member of the compound class of statins, used to treat high cholesterol and related conditions, and to prevent cardiovascular disease. Rosuvastatin is a competitive inhibitor of the enzyme HMG-CoA reductase, having a mechanism of action similar to that of other statins.
Atherosclerosis. 2019 Nov;290:19-30.
Lysophosphatidic acid decreased macrophage foam cell migration correlated with downregulation of fucosyltransferase 8 via HNF1α.
Rosuvastatin calcium purchased from AbMole
Pak J Pharm Sci. 2016 May;29(3 Suppl):1043-51.
Chromatographic resolution of drug analogues: 3-hydroxy-3-methylglutarylcoenzyme A reductase inhibitors (statins)
Rosuvastatin calcium purchased from AbMole
Molecular Weight | 500.57 |
Formula | C44H54CaF2N6O12S2 |
CAS Number | 147098-20-2 |
Solubility (25°C) | DMSO 30 mg/mL |
Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[2] Yvette N Lamb. Rosuvastatin/Ezetimibe: A Review in Hypercholesterolemia
[4] Gurpreet S Wander, et al. Rosuvastatin: Role in Secondary Prevention of Cardiovascular Disease
[5] Francesca Cortese, et al. Rosuvastatin: Beyond the cholesterol-lowering effect
Related HMG-CoA Reductase Products |
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Dalvastatin
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(3S,5R)-Fluvastatin sodium
(3S,5R)-Fluvastatin sodium ((3S,5R)-XU 62-320) is the (3S,5R)-enantiomer of Fluvastatin. |
Fluvastatin
Fluvastatin is the first fully synthesized, competitive HMG-CoA reductase inhibitor with an IC50 of 8 nM.Fluvastatin protects vascular smooth muscle cells from oxidative stress through an Nrf2-dependent antioxidant pathway. |
Pravastatin lactone
Pravastatin lactone is a potent HMG-CoA inhibitor. |
HMG-CoA Reductase-IN-1
HMG-CoA Reductase-IN-1 is a HMG-CoA reductase inhibitor. |
All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.
Products are for research use only. Not for human use. We do not sell to patients.
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