Free shipping on all orders over $ 500

Rosuvastatin calcium

Cat. No. M2283

All AbMole products are for research use only, cannot be used for human consumption.

Rosuvastatin calcium Structure
Synonym:

Crestor; ZD 4522 Calcium

Size Price Availability Quantity
Free Sample (0.5-1 mg)  USD 0 In stock
10mM*1mL in DMSO USD 28  USD28 In stock
10mg USD 30  USD30 In stock
50mg USD 50  USD50 In stock
100mg USD 95  USD95 In stock
200mg USD 150  USD150 In stock
Free Delivery on orders over USD 500 Bulk Inquiry?

Quality Control & Documentation
Biological Activity

Rosuvastatin (Crestor) is a member of the compound class of statins, used to treat high cholesterol and related conditions, and to prevent cardiovascular disease. Rosuvastatin is a competitive inhibitor of the enzyme HMG-CoA reductase, having a mechanism of action similar to that of other statins.

Product Citations
Customer Product Validations & Biological Datas
Source Pak J Pharm Sci (2016). Figure 1. Rosuvastatin calcium (Abmole Bioscience)
Method HPLC chromatogram
Cell Lines
Concentrations 200μg/ml
Incubation Time
Results The results summarized in (table 1) obtained for pravastatin, rosuvastatin, pitavastatin, atorvastatin, fluvastatin, lovastatin and simvastatin were comparable with the corresponding labeled amounts.
Chemical Information
Molecular Weight 500.57
Formula C44H54CaF2N6O12S2
CAS Number 147098-20-2
Solubility (25°C) DMSO 30 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Xuan Jin, et al. Efficacy and safety of co-administered telmisartan/amlodipine and rosuvastatin in subjects with hypertension and dyslipidemia

[2] Yvette N Lamb. Rosuvastatin/Ezetimibe: A Review in Hypercholesterolemia

[3] Larysa Strilchuk, et al. An overview of rosuvastatin/ezetimibe association for the treatment of hypercholesterolemia and mixed dyslipidemia

[4] Gurpreet S Wander, et al. Rosuvastatin: Role in Secondary Prevention of Cardiovascular Disease

[5] Francesca Cortese, et al. Rosuvastatin: Beyond the cholesterol-lowering effect

Related HMG-CoA Reductase Products
Dalvastatin

Dalvastatin (RG-12561) inhibitor of HMG-CoA reductase and cholesterol-lowering synthesis.

(3S,5R)-Fluvastatin sodium

(3S,5R)-Fluvastatin sodium ((3S,5R)-XU 62-320) is the (3S,5R)-enantiomer of Fluvastatin.

Fluvastatin

Fluvastatin is the first fully synthesized, competitive HMG-CoA reductase inhibitor with an IC50 of 8 nM.Fluvastatin protects vascular smooth muscle cells from oxidative stress through an Nrf2-dependent antioxidant pathway.

Pravastatin lactone

Pravastatin lactone is a potent HMG-CoA inhibitor.

HMG-CoA Reductase-IN-1

HMG-CoA Reductase-IN-1 is a HMG-CoA reductase inhibitor.

  Catalog
Abmole Inhibitor Catalog




Keywords: Rosuvastatin calcium, Crestor; ZD 4522 Calcium supplier, HMG-CoA Reductase, inhibitors, activators

All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.



Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2024 AbMole BioScience. All Rights Reserved.