About 27 results found for searched term "PAD" (0.051 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M2954 | PPADS Tetrasodium | P2 Receptor |
| PPADS tetrasodium salt is a non-selective P2 purinergic antagonist blocking recombinant P2X1, P2X2, P2X3, P2X5 with IC50 of 1-2.6 μM, native P2Y2-like with IC50 of ~ 0.9 mM, and recombinant P2Y4 receptors with IC50 of ~ 15 mM | ||
| M5065 | Cebranopadol | Opioid Receptor |
| GRT-6005 | ||
| Cebranopadol is a NOP and opioid receptor agonist that acts on human NOP, MOP, KOP and δ-opioid peptide (DOP) receptors with Ki/EC50 values of 0.9 nM/13 nM and 0.7 nM/1.2 nM, respectively. 2.6 nM/17 nM, 18 nM/110 nM. | ||
| M5762 | Mebhydrolin napadisylate | Histone demethylase |
| Mebhydroline 1,5-naphthalenedisulfonate salt | ||
| Mebhydrolin (napadisylate) is an antihistamine, used for symptomatic relief of allergic symptoms caused by histamine release, including nasal allergies and allergic dermatosis. | ||
| M6297 | Upadacitinib | JAK |
| ABT-494 | ||
| Upadacitinib (ABT-494) is a potent, orally active and selective Janus kinase 1 (JAK1) inhibitor (IC50=43 nM). Upadacitinib (ABT-494) displays approximately 74 fold selective for JAK1 over JAK2 (200 nM) in cellular assays dependent on specific, relevant cytokines. Upadacitinib (ABT-494) can be used for several autoimmune disorders research. | ||
| M9799 | Capadenoson | Adenosine Receptor |
| BAY 68-4986 | ||
| Capadenoson (BAY 68-4986) is an oral active, potent and selective adenosine A1 receptor agonist. | ||
| M10191 | Vipadenant | Adenosine Receptor |
| BIIB014; CEB-4520 | ||
| Vipadenant, also known as BIIB014, CEB-4520, is a potent, selective and orally available adenosine A2A receptor antagonist with Ki of 1.3 nM. | ||
| M14247 | PPADS | P2 Receptor |
| PPADS is a non-selective P2X receptor antagonist. PPADS acts as an ATP (nucleotide) mimetic and competes with ATP for its binding site on P2 receptors. PPADS is also a reversible competitive antagonist of the NAADP receptor. | ||
| M16176 | Hippadine | Alkaloids |
| Hippadine | ||
| M16814 | Padmatin | Flavonoids |
| Padmatin | ||
| M17218 | Pterocarpadiol A | Phenols |
| Pterocarpadiol A | ||
| M21473 | Padsevonil | Others |
| UCB-0942 | ||
| Padsevonil (UCB0942) is the first effective antiepileptic agent. Padsevonil can be used in the study of epilepsy. | ||
| M25169 | Mupadolimab | Others |
| CPI-006 | ||
| Mupadolimab (CPI-006) is an IgG1κ humanized FcγR binding-deficient anti-CD73 monoclonal antibody (mAb) that activates CD73POS B cells. | ||
| M28766 | Tavapadon | Dopamine Receptor |
| PF-06649751; CVL-751 | ||
| Tavapadon (PF-06649751) is a potentially best-in-class, orally active, highly selective dopamine D1/D5 receptor partial agonist for studies related to Parkinson's disease (PD). | ||
| M29428 | Inupadenant | Adenosine Receptor |
| EOS-850 | ||
| Inupadenant is an orally active, highly selective A2A receptor antagonist. Inupadenant is not brain-penetrant. Inupadenant has potent anti-tumor activity. | ||
| M40871 | AFM32a | Others |
| PAD2-IN-1 | ||
| AFM32a is a benzimidazole-based derivative and a potent and selective protein arginine deiminase 2 (PAD2) inhibitor.AFM32a is more selective for PAD2 than PAD4 (95-fold) and PAD3 (79-fold). | ||
| M40872 | AFM32a hydrochloride | Others |
| PAD2-IN-1 hydrochloride | ||
| AFM32a hydrochloride is a benzimidazole-based derivative and a potent and selective protein arginine deiminase 2 (PAD2) inhibitor.AFM32a hydrochloride is more selective for PAD2 than PAD4 (95-fold) and PAD3 (79-fold). | ||
| M41344 | Lepadin E | Glutathione Peroxidase |
| Lepadin E is a significantly cytotoxic ferroptosis inducer that induces iron death through the classical p53-SLC7A11-GPX4 pathway. | ||
| M41728 | PAD4-IN-2 | PAD |
| PAD4-IN-2 is a PAD4 inhibitor (IC50=1.94 μM). | ||
| M41761 | Inupadenant hydrochloride | Adenosine Receptor |
| Inupadenant (EOS-850) hydrochloride is an orally active, highly selective A2A receptor antagonist. | ||
| M43738 | 3-epi-Padmatin | Others |
| 3-epi-Padmatin is a natural product that can be isolated from Inula graveolens. | ||
| M43933 | Apadamtase alfa | Others |
| Apadamtase alfa is a vWFCP modulator that can be used in studies related to cTTP in chronic coagulation disorders. | ||
| M49634 | Upadacitinib tartrate tetrahydrate | JAK |
| Upadacitinib (ABT-494) tartrate tetrahydrate is a potent, orally active and selective Janus kinase 1 (JAK1) inhibitor (IC50=43 nM). | ||
| M52749 | Spadin | Potassium Channel |
| Spadin, a natural peptide derived from a propeptide released in blood, is a potent TREK-1 channel blocker with IC50 value of 10 nM. | ||
| M56544 | Iso-PPADS tetrasodium | P2 Receptor |
| Iso-PPADS tetrasodium is a P2X-purinoceptor antagonist. | ||
| M56472 | Lesogaberan napadisylate | GABA Receptor |
| Lesogaberan (AZD-3355) napadisylate is a potent and selective GABAB receptor agonist with an EC50 of 8.6 nM for human recombinant GABAB receptors. | ||
| M56108 | Apadenoson | Adenosine Receptor |
| Apadenoson is an adenosine analog with selective agonist activity for the adenosine A2a receptor and induces coronary vasodilatation. | ||
| M57535 | 5-Cl-PADAB | Others |
| 5-Cl-PADAB | ||
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