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Lepadin E

Cat. No. M41344

All AbMole products are for research use only, cannot be used for human consumption.

Lepadin E Structure

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Quality Control & Documentation
Biological Activity

Lepadin E is a significantly cytotoxic ferroptosis inducer that induces iron death through the classical p53-SLC7A11-GPX4 pathway.

Chemical Information
Molecular Weight 421.66
Formula C26H47NO3
CAS Number 444914-19-6
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Wenjun Wang et al. J Med Chem. Marine Alkaloid Lepadins E and H Induce Ferroptosis for Cancer Chemotherapy

[2] Xiaotao Pu et al. Angew Chem Int Ed Engl. Total synthesis of lepadins B, d, e, and h; determination of the configuration of the latter three alkaloids

[3] Anthony D Wright et al. J Med Chem. Lepadins D-F: antiplasmodial and antitrypanosomal decahydroquinoline derivatives from the tropical marine tunicate Didemnum sp

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Keywords: Lepadin E supplier, Glutathione Peroxidase, inhibitors, activators

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