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AFM32a hydrochloride is a benzimidazole-based derivative and a potent and selective protein arginine deiminase 2 (PAD2) inhibitor.AFM32a hydrochloride is more selective for PAD2 than PAD4 (95-fold) and PAD3 (79-fold).
| Molecular Weight | 517.00 |
| Formula | C25H30ClFN6O3 |
| CAS Number | 2095109-82-1 (free base) |
| Form | Solid |
| Solubility (25°C) | DMSO 100 mg/mL |
| Storage | 4°C, protect from light, dry, sealed |
[2] Chuangchuang Xu et al. Org Biomol Chem. Metal-free and regiospecific synthesis of 3-arylindoles
[4] S Groszkowski et al. Pol J Pharmacol Pharm. 1-Haloacylpiperazines
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