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About 30 results found for searched term "NOS" (0.002 seconds)
| Cat.No. | Name | Information |
|---|---|---|
| M1670 | Belinostat | Belinostat (PXD101) is a novel HDAC inhibitor with an IC50 of 27 nM. |
| M6229 | Kanamycin sulfate | Kanamycin sulfate is an aminoglycoside antibiotic that acts as a bacteriostatic agent by binding to the bacterial 30S ribosome. |
| M1730 | Givinostat hydrochloride monohydrate | ITF2357 (Givinostat, Gavinostat) is a histone deacetylase inhibitor. The IC50 values for maize HDAC preparations HD2, HD-1B and HD-1A are 10, 7.5 and 16 nM respectively. |
| M1735 | BGT226 | BGT226 (NVP-BGT226) is a novel phosphoinositide 3-kinase/mTOR dual inhibitor. |
| M1739 | PKI-179 | PKI-179 is an orally dual phosphatidylinositol-3-kinase (PI3K)/mammalian target of rapamycin (mTOR) inhibitor with potential antineoplastic activity. |
| M1748 | LBH589 (Panobinostat) | LBH589 (Panobinostat) is a novel broad-spectrum HDAC inhibitor for MOLT-4 and Reh cells with IC50 of 5 and 20 nM, respectively. |
| M1778 | SB939 | SB939 is a novel potent and orally active histone deacetylase with high tumor exposure and efficacy in mouse models of colorectal cancer. |
| M1780 | Vorinostat | Vorinostat (SAHA, Zolinza, MK-0683) is a selective and potent histone deacetylase (HDAC) inhibitor with the IC50 value of 10 nM for HDAC-1. |
| M1790 | MGCD0103 | MGCD0103 is a novel HDAC inhibitor, highly specific for classes I and IV HDACs, with IC50 of 0.15, 0.29 and 1.66 μM for HDAC 1, HDAC 2 and HDAC 3 respectively. |
| M1791 | Entinostat (MS-275) | Entinostat (MS-275) is an oral and selective class I HDAC inhibitor, with IC50s of 243 nM, 453 nM, and 248 nM for HDAC1, HDAC2, and HDAC3, respectively. |
| M1795 | TGX-221 | TGX-221 is a potent and specific cell permeable inhibitor of Phosphatidylinositol 3-kinase (PI3K) p110β(IC50 = 10nM). |
| M1813 | PCI-24781 | PCI-24781 is a novel and potent histone deacetylase (HDAC) inhibitor with IC50 value of 0.43 to 2.7 μM.*The compound is unstable in solutions, freshly prepared is recommended |
| M1831 | Cyclosporine A | Cyclosporin A is an immunosuppressant that binds to cyclophilin and inhibits calcineurin with an IC50 of 7 nM. cyclosporin A [CsA] binds to the cyclophilin 18 (Cyp18)-CsA complex. the Cyp18-CsA complex recruits calcium-regulated neurophosphatase (CaN), leading to the blocking of cytokine gene transcription in activated T cells. CsA is a highly specific inhibitor of T-cell activation. |
| M9217 | Givinostat | Givinostat is an HDAC inhibitor with IC50s of 198 and 157 nM for HDAC1 and HDAC3, respectively. |
| M1864 | SYN115 | SYN115 is a novel, selective adenosine A(2A) receptor antagonist. |
| M1878 | ZSTK474 | ZSTK474 is an ATP-competitive inhibitor of class I phosphatidylinositol 3-kinase (PI3K), induces G1 arrest of the cell cycle in vivo. |
| M1921 | Mizoribine | Mizoribine (Bredinin) is an imidazole nucleoside and an immunosuppressive agent with an IC50 of approximately 100 μM. |
| M1931 | GSK2126458 | GSK2126458 is a highly potent inhibitor of phosphoinositide 3-kinase (PI3K) and mammalian target of rapamycin (mTOR) with low picomolar to subnanomolar activity. |
| M1934 | Tacrolimus (FK506) | Tacrolimus (FK506, FR900506, Fujimycin, Prograf) is a potent, clinically-useful immunosuppressant in the same molecular class as cyclosporin A and rapamycin. *The compound is unstable in solutions, freshly prepared is recommended |
| M11338 | Carminic Acid (Natural dye) | Carminic acid is an anthraquinone red dye. Carminic acid is used for human-medical cell diagnosis and serves the purpose of the histological investigation of sample material of human origin. |
| M1993 | Droxinostat | Droxinostat is a selective inhibitor of HDAC3, HDAC6 and HDAC8 with IC50 of 16.9 μM, 2.47μM and 1.46 μM, respectively. |
| M2011 | PP121 | PP121 is a dual inhibitor of tyrosine and phosphoinositide kinases. |
| M2053 | Wortmannin (KY 12420) | Wortmannin (KY 12420) is a specific, covalent inhibitor of phosphatidylinositol 3-kinase (PI 3-kinase) with IC50 of 3 nM. |
| M2073 | Duvelisib (IPI-145) | Duvelisib (IPI-145) is a potent, oral inhibitor of phosphoinositide-3-kinase (PI3K)-delta and PI3K-gamma. |
| M2111 | CUDC-907 | CUDC-907 is a potent, orally-available small molecule dual PI3K and HDAC inhibitor. |
| M2114 | GSK126 | GSK126 is a potent, highly selective, S-adenosyl-methionine-competitive, small-molecule inhibitor of EZH2 methyltransferase activity. |
| M2119 | JNJ-26481585 | JNJ-26481585 (Quisinostat) is a novel second-generation class I HDAC inhibitor. |
| M2123 | Rocilinostat | Rocilinostat (ACY-1215) is an HDAC6-selective inhibitor with IC50 of 5 nM. |
| M2175 | Palonosetron hydrochloride | Palonosetron hydrochloride is a novel antiemetic 5-HT3-receptor antagonist. |
| M2211 | Rigosertib sodium | Rigosertib sodium is a dual non-ATP inhibitor of polo-like kinase 1 (Plk1) and phosphoinositide 3-kinase pathways (PI3K). |
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