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 About 30 results found for searched term "NOS" (0.004 seconds)

Cat.No.  Name Target
M1670 Belinostat HDAC
PXD101; PX105684
Belinostat (PXD101) is a novel HDAC inhibitor with an IC50 of 27 nM.
M6229 Kanamycin sulfate Antibiotic
Kanamycin A monosulfate
Kanamycin sulfate is an aminoglycoside antibiotic that acts as a bacteriostatic agent by binding to the bacterial 30S ribosome.
M1730 Givinostat hydrochloride monohydrate HDAC
ITF-2357 hydrochloride monohydrate
ITF2357 (Givinostat, Gavinostat) is a histone deacetylase inhibitor. The IC50 values for maize HDAC preparations HD2, HD-1B and HD-1A are 10, 7.5 and 16 nM respectively.
M1748 LBH589 (Panobinostat) HDAC
NVP-LBH589, Panobinostat
LBH589 (Panobinostat) is a novel broad-spectrum HDAC inhibitor for MOLT-4 and Reh cells with IC50 of 5 and 20 nM, respectively.
M1778 SB939 HDAC
SB939 is a novel potent and orally active histone deacetylase with high tumor exposure and efficacy in mouse models of colorectal cancer.
M1780 Vorinostat HDAC
SAHA; Zolinza; MK-0683; Suberoylanilide hydroxamic acid
Vorinostat (SAHA, Zolinza, MK-0683) is a selective and potent histone deacetylase (HDAC) inhibitor with the IC50 value of 10 nM for HDAC-1.
M1790 MGCD0103 HDAC
MGCD0103 is a novel HDAC inhibitor, highly specific for classes I and IV HDACs, with IC50 of 0.15, 0.29 and 1.66 μM for HDAC 1, HDAC 2 and HDAC 3 respectively.
M1791 Entinostat (MS-275) HDAC
SNDX-275, MS-27-275
Entinostat (MS-275) is an oral and selective class I HDAC inhibitor, with IC50s of 243 nM, 453 nM, and 248 nM for HDAC1, HDAC2, and HDAC3, respectively.
M1813 PCI-24781 HDAC
Abexinostat; CRA-024781
PCI-24781 is a novel and potent histone deacetylase (HDAC) inhibitor with IC50 value of 0.43 to 2.7 μM. *The compound is unstable in solutions, freshly prepared is recommended
M9217 Givinostat HDAC
Givinostat is an HDAC inhibitor with IC50s of 198 and 157 nM for HDAC1 and HDAC3, respectively.
M1993 Droxinostat HDAC
NS 41080
Droxinostat is a selective inhibitor of HDAC3, HDAC6 and HDAC8 with IC50 of 16.9 μM, 2.47μM and 1.46 μM, respectively.
M2111 CUDC-907 HDAC
CUDC-907 is a potent, orally-available small molecule dual PI3K and HDAC inhibitor.
M2119 JNJ-26481585 HDAC
JNJ-26481585 (Quisinostat) is a novel second-generation class I HDAC inhibitor.
M2123 Rocilinostat HDAC
ACY-1215; Ricolinostat
Rocilinostat (ACY-1215) is an HDAC6-selective inhibitor with IC50 of 5 nM.
M2175 Palonosetron hydrochloride 5-HT Receptor
Palonosetron hydrochloride is a novel antiemetic 5-HT3-receptor antagonist.
M2292 Cytarabine DNA/RNA Synthesis
Cytosine β-D-arabinofuranoside; Cytosine Arabinoside; Ara-C
Cytarabine (Cytosine arabinoside, AraC) is an antimetabolic agent and DNA synthesis inhibitor with IC50 of 16 nM.
M2849 Microcystin-LR Phosphatase
Cyanoginosin-LR; MC-LR; Toxin T 17 (Microcystis aeruginosa)
Microcystin-LR is a potent protein phosphatase inhibitor with IC50 of 0.04 nM for PP2A, >40-fold selectivity over PP1.
M2888 Noscapine hydrochloride Microtubule
Noscapine, a phthalideisoquinoline alkaloid constituting 1–10% of the alkaloid content of opium, has been used as a cough suppressant.
M2914 Paromomycin Sulfate Antibiotic
Aminosidine sulfate; Paromomycin sulfate salt
Paromomycin Sulfate is an aminoglycoside antibioticis inhibiting protein synthesis in non-resistant cells by binding to 16S ribosomal RNA.
M2995 Salinosporamide A Proteasome
(-)-Salinosporamide A; ML 858; NPI 0052; Marizomib
Salinosporamide A (NPI-0052, Marizomib) is a novel marine derived proteasome inhibitor which inhibits CT-L, C-L, and T-L proteasome activities in human erythrocyte-derived 20S proteasomes with EC50 of 3.5 nM, 430 nM, 28 nM.
M3017 Sodium 4-Aminosalicylate NF-κB
4-Aminosalicylic acid
Sodium 4-Aminosalicylate is an antibiotic used to treat tuberculosis via NF-κB inhibition and free radical scavenging.
M3292 Adenosine Metabolite/Endogenous Metabolite
Adenine riboside; D-Adenosine
Adenosine is a nucleoside composed of a molecule of adenine attached to a ribose sugar molecule (ribofuranose) moiety via a β-N9-glycosidic bond.
M3355 Didanosine Reverse Transcriptase
2',3'-Dideoxyinosine; ddI
Didanosine is a reverse transcriptase inhibitor with an IC50 of 0.49 μM.
M3533 Spectinomycin hydrochloride Antibiotic
Spectinomycin hydrochloride is a new parenteral antibiotic prepared from Streptomyces spectabilis.
M3894 Rutin Amyloid
Rutoside; Quercetin 3-O-rutinoside
Rutin is a flavonol glycoside found in many plants including buckwheat, tobacco, forsythia, hydrangea, viola, etc., which possesses healthy effects for human.
M3904 Pulchinenoside A GluR
Anemoside A3
Pulchinenoside can inhibit abnormal proliferation of synovial membrane by modulating Wnt pathway of RA rats.Pulchinenoside may inhibit the FLS proliferation in AA rats by increase in FLS apoptosis.
M3905 Anemoside B4 Others
Chinensioside A, Pulchinenoside C, Pulchinenoside B4
Pulchinenoside C (Anemoside B4) is a natural Pulchinenoside B4, which has many biological effects, such as anti-tumor, neuroprotective, anti-angiogenic and other activities.
M3926 Cynaroside Akt
Cynaroside is a flavone, a flavonoid-like chemical compound. It is a 7-O-glucoside of luteolin.
M3940 Ginsenoside Rg1 Amyloid
G-Rg1; Panaxoside Rg1
Ginsenoside Rg1 is part of a class of triterpene saponins and steroid glycosides. Ginsenoside Rg1 ameliorates the impaired cognitive function, displays promising effects by reducing cerebral Aβ levels. It is found exclusively in the plant genus Panax, or ginseng.
M3987 Ginsenoside Rb1 Sodium Channel
Gynosaponin C; Gypenoside III
Ginsenoside Rb1 is an ingredient in the Chinese medicine Panax ginseng. Ginsenoside inhibition Na, K-ATPase++ activityIC50 6.3±1.0 μM. Ginsenoside Rb1 also inhibits IRAK-1 activation and phosphorylation of NF-κB p65.

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