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 About 30 results found for searched term "NOS" (0.002 seconds)

Cat.No.  Name Information
M1670 Belinostat Belinostat (PXD101) is a novel HDAC inhibitor with an IC50 of 27 nM.
M6229 Kanamycin sulfate Kanamycin sulfate is an aminoglycoside antibiotic that acts as a bacteriostatic agent by binding to the bacterial 30S ribosome.
M1730 Givinostat hydrochloride monohydrate ITF2357 (Givinostat, Gavinostat) is a histone deacetylase inhibitor. The IC50 values for maize HDAC preparations HD2, HD-1B and HD-1A are 10, 7.5 and 16 nM respectively.
M1735 BGT226 BGT226 (NVP-BGT226) is a novel phosphoinositide 3-kinase/mTOR dual inhibitor.
M1739 PKI-179 PKI-179 is an orally dual phosphatidylinositol-3-kinase (PI3K)/mammalian target of rapamycin (mTOR) inhibitor with potential antineoplastic activity.
M1748 LBH589 (Panobinostat) LBH589 (Panobinostat) is a novel broad-spectrum HDAC inhibitor for MOLT-4 and Reh cells with IC50 of 5 and 20 nM, respectively.
M1778 SB939 SB939 is a novel potent and orally active histone deacetylase with high tumor exposure and efficacy in mouse models of colorectal cancer.
M1780 Vorinostat Vorinostat (SAHA, Zolinza, MK-0683) is a selective and potent histone deacetylase (HDAC) inhibitor with the IC50 value of 10 nM for HDAC-1.
M1790 MGCD0103 MGCD0103 is a novel HDAC inhibitor, highly specific for classes I and IV HDACs, with IC50 of 0.15, 0.29 and 1.66 μM for HDAC 1, HDAC 2 and HDAC 3 respectively.
M1791 Entinostat (MS-275) Entinostat (MS-275) is an oral and selective class I HDAC inhibitor, with IC50s of 243 nM, 453 nM, and 248 nM for HDAC1, HDAC2, and HDAC3, respectively.
M1795 TGX-221 TGX-221 is a potent and specific cell permeable inhibitor of Phosphatidylinositol 3-kinase (PI3K) p110β(IC50 = 10nM).
M1813 PCI-24781 PCI-24781 is a novel and potent histone deacetylase (HDAC) inhibitor with IC50 value of 0.43 to 2.7 μM.*The compound is unstable in solutions, freshly prepared is recommended
M1831 Cyclosporine A Cyclosporin A is an immunosuppressant that binds to cyclophilin and inhibits calcineurin with an IC50 of 7 nM. cyclosporin A [CsA] binds to the cyclophilin 18 (Cyp18)-CsA complex. the Cyp18-CsA complex recruits calcium-regulated neurophosphatase (CaN), leading to the blocking of cytokine gene transcription in activated T cells. CsA is a highly specific inhibitor of T-cell activation.
M9217 Givinostat Givinostat is an HDAC inhibitor with IC50s of 198 and 157 nM for HDAC1 and HDAC3, respectively.
M1864 SYN115 SYN115 is a novel, selective adenosine A(2A) receptor antagonist.
M1878 ZSTK474 ZSTK474 is an ATP-competitive inhibitor of class I phosphatidylinositol 3-kinase (PI3K), induces G1 arrest of the cell cycle in vivo.
M1921 Mizoribine Mizoribine (Bredinin) is an imidazole nucleoside and an immunosuppressive agent with an IC50 of approximately 100 μM.
M1931 GSK2126458 GSK2126458 is a highly potent inhibitor of phosphoinositide 3-kinase (PI3K) and mammalian target of rapamycin (mTOR) with low picomolar to subnanomolar activity.
M1934 Tacrolimus (FK506) Tacrolimus (FK506, FR900506, Fujimycin, Prograf) is a potent, clinically-useful immunosuppressant in the same molecular class as cyclosporin A and rapamycin. *The compound is unstable in solutions, freshly prepared is recommended
M11338 Carminic Acid (Natural dye) Carminic acid is an anthraquinone red dye. Carminic acid is used for human-medical cell diagnosis and serves the purpose of the histological investigation of sample material of human origin.
M1993 Droxinostat Droxinostat is a selective inhibitor of HDAC3, HDAC6 and HDAC8 with IC50 of 16.9 μM, 2.47μM and 1.46 μM, respectively.
M2011 PP121 PP121 is a dual inhibitor of tyrosine and phosphoinositide kinases.
M2053 Wortmannin (KY 12420) Wortmannin (KY 12420) is a specific, covalent inhibitor of phosphatidylinositol 3-kinase (PI 3-kinase) with IC50 of 3 nM.
M2073 Duvelisib (IPI-145) Duvelisib (IPI-145) is a potent, oral inhibitor of phosphoinositide-3-kinase (PI3K)-delta and PI3K-gamma.
M2111 CUDC-907 CUDC-907 is a potent, orally-available small molecule dual PI3K and HDAC inhibitor.
M2114 GSK126 GSK126 is a potent, highly selective, S-adenosyl-methionine-competitive, small-molecule inhibitor of EZH2 methyltransferase activity.
M2119 JNJ-26481585 JNJ-26481585 (Quisinostat) is a novel second-generation class I HDAC inhibitor.
M2123 Rocilinostat Rocilinostat (ACY-1215) is an HDAC6-selective inhibitor with IC50 of 5 nM.
M2175 Palonosetron hydrochloride Palonosetron hydrochloride is a novel antiemetic 5-HT3-receptor antagonist.
M2211 Rigosertib sodium Rigosertib sodium is a dual non-ATP inhibitor of polo-like kinase 1 (Plk1) and phosphoinositide 3-kinase pathways (PI3K).

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