About 30 results found for searched term "MID-1" (0.065 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M1839 | MDV3100 | Androgen Receptor |
| Enzalutamide; MDV-3100 | ||
| MDV3100 is an orally bioavailable, organic, non-steroidal small molecule targeting the androgen receptor (AR) with potential antineoplastic activity. | ||
| M1962 | Lenalidomide | TNF Receptor |
| Revlimid, CC-5013 | ||
| Lenalidomide is a thalidomide analog known to display TNF-α secretion inhibition and possesses immunomodulatory properties. | ||
| M3358 | Procainamide hydrochloride | Sodium Channel |
| Procaine amide hydrochloride; SP 100 hydrochloride | ||
| Procainamide hydrochloride is a sodium channel blocker, and also a DNA methyltransferase inhibitor. | ||
| M3379 | Trifluridine | DNA/RNA Synthesis |
| Trifluridine; FTD; 5-Trifluorothymidine; NSC 529182; NSC 75520 | ||
| Trifluridine (Trifluorothymidine) is an irreversible and orally active thymidylate synthase inhibitor, and thereby suppressing DNA synthesis. Trifluridine is an antiviral molecule used for research of HSV, rhabdovirus and orthopoxvirus infection. | ||
| M3708 | Anastrozole | Cytochrome P450 (e.g. CYP17) |
| Arimidex, ZD1033 | ||
| Anastrozole is a potent and highly selective aromatase (CYP19) inhibitor (IC50 = 15 nM) that has no discernible effect on adrenocorticoid hormone synthesis. | ||
| M5479 | Carsalam | Others |
| Carbonylsalicylamide; 2H-1,3-Benzoxazine-2,4(3H)-dione | ||
| Carsalam (Carbonylsalicylamide) is a non-steroidal anti-inflammatory compound. | ||
| M5908 | Prothionamide | Antibiotic |
| Prothionamide, 1321-TH | ||
| Protionamide is a compound used to study tuberculosis. | ||
| M7374 | TC-H 106 | HDAC |
| Pimelic Diphenylamide 106; RGFA-8; Histone Deacetylase Inhibitor VII | ||
| TC-H 106 is a class I histone deacetylase inhibitor, with IC50 values of 150 nM , 760 nM and 370 nM for HDAC 1, 2, and 3, respectively. | ||
| M8535 | Bis-Imidazole phenol IDH1 inhibitor | Isocitrate Dehydrogenase (IDH) |
| bis-Imidazole phenol is a potent and cell permeable inhibitor of isocitrate dehydrogenase 1 (IDH1) mutant R132H that inhibits D-2-hydroxyglutaric acid (2HG) production in cells. | ||
| M8964 | Thymidine | DNA/RNA Synthesis |
| DThyd; Deoxyribothymidine; NSC 21548 | ||
| Thymidine is a pyrimidine nucleoside that is composed of the pyrimidine base thymine attached to the sugar deoxyribose. | ||
| M9230 | Indole-3-acetamide | Plant growth regulators |
| 3-Indolylacetamide; NSC 1969 | ||
| Indole-3-acetamide is an auxin precursor. | ||
| M9710 | Roquinimex | TNF Receptor |
| LS2616; FCF89; Linomide; ABR212616 | ||
| Roquinimex (LS2616; FCF89) is a quinoline-3-carboxamide with potential antineoplastic activity, which increases NK cell activity and macrophage cytotoxicity. | ||
| M9729 | diABZI (tautomerism) | STING |
| Diamidobenzimidazole STING Agonist-1 (tautomerism) | ||
| diABZI (STING agonist 1; Tautomerism) is a selective stimulator of interferon genes (STING) receptor agonist, with EC50s of 130, 186 nM for human and mouse, respectively. | ||
| M10285 | MID-1 | Others |
| MID1 | ||
| MID-1 is an inhibitor of MG53-IRS-1 (Mitsugumin 53-Insulin Receptor Substrate-1) interaction. | ||
| M10306 | Bavdegalutamide (ARV-110) | Androgen Receptor |
| ARV110 | ||
| Bavdegalutamide (ARV-110) is an oral, specific androgen receptor (AR) PROTAC degrader. | ||
| M10865 | Poly-D-lysine hydrobromide (150,000-300,000) | Cell Culture |
| Poly-D-lysine HBr | ||
| Poly-D-lysine hydrobromide (MW 150,000-300,000) is a synthetic polymeric substrate and is one of the most widely used substrate in neural cell culture. | ||
| M11319 | GLP-1(7-36), amide TFA | GLP Receptor |
| Glucagon-like peptide-1 (GLP-1)(7-36), amide TFA; Human GLP-1 (7-36), amide TFA | ||
| TFA is a major intestinal hormone that stimulates insulin secretion by pancreatic beta cells in response to glucose. | ||
| M11332 | diABZI trihydrochloride | STING |
| Diamidobenzimidazole STING Agonist-1 3HCl | ||
| diABZI (STING agonist-1) trihydrochloride is a selective agonist of interferon gene-stimulated receptor (STING), with EC50 scores of 130 nM and 186 nM in mice and humans, respectively. | ||
| M11549 | Palifosfamide | DNA Alkylator/Crosslinker |
| Isophosphoramide mustard; IPM; ZIO-201 | ||
| Palifosfamide(Isophosphoramide mustard; IPM; Zio-201) is a new DNA alkylation agent and active metabolite of isocyclophosphamide, which has anticancer activity. | ||
| M13816 | Procainamide | DNA Methyltransferase |
| Procaine amide; SP 100 | ||
| Procainamide is a specific and potent inhibitor of DNA methyltransferase 1 (DNMT1). Procainamide is a Class 1A antiarrhythmic agent. Procainamide has the potential for the research of cancer and arrhythmias. | ||
| M13968 | GLP-1(7-36), amide acetate | GLP Receptor |
| Glucagon-like peptide-1 (GLP-1)(7-36), amide acetate; Human GLP-1 (7-36), amide acetate | ||
| GLP-1(7-36), amide acetate is a major intestinal hormone that stimulates glucose-induced insulin secretion from β cells. | ||
| M14123 | diABZI | STING |
| Diamidobenzimidazole STING Agonist-1; diABZI STING agonist-1 | ||
| diABZI (Diamidobenzimidazole STING Agonist-1) is a selective stimulator of interferon genes (STING) receptor agonist, with EC50s of 130, 186 nM for human and mouse, respectively. | ||
| M14134 | Rociletinib hydrobromide | EGFR/HER2 |
| CO-1686 hydrobromide; AVL-301 hydrobromide; CNX-419 hydrobromide | ||
| Rociletinib hydrobromide (CO-1686 hydrobromide) is an orally delivered kinase inhibitor that specifically targets the mutant forms of EGFR including T790M, and the Ki values for EGFRL858R/T790M and EGFRWT are 21.5 nM and 303.3 nM, respectively. | ||
| M14592 | CDDO-EA | Keap1-Nrf2 |
| CDDO ethyl amide; TP319; RTA 405 | ||
| CDDO-EA is an NF-E2 related factor 2/antioxidant response element (Nrf2/ARE) activator. | ||
| M14754 | Pimelic Diphenylamide 106 (analog) | Others |
| RGFA-8 analog; TC-H 106 analog | ||
| Pimelic Diphenylamide 106 analog is an analog of Pimelic Diphenylamide 106 with unknown biological activity. | ||
| M18241 | N-Benzylpalmitamide | FAAH |
| Macamide 1; N-Benzylhexadecanamide | ||
| N-Benzylpalmitamide is a macamide isolated from Lepidium meyenii, acts as an inhibitor of fatty acid amide hydrolase (FAAH). | ||
| M19930 | Cefpiramide acid | Anti-infection |
| Cefpiramide acid; Cefpiramido; Cefpiramidum; WY-44635; SM-1652 | ||
| Cefpiramide (Cefpiramide acid, Cefpiramido, Cefpiramidum, WY-44635, SM-1652) is a pseudomonas-active cephalosporin with a broad spectrum of antibacterial activity. | ||
| M20414 | PTP Inhibitor I | Phosphatase |
| α-Bromo-4-hydroxyacetophenone, 2-Bromo-4'-hydroxyacetophenone, 4-Hydroxyphenacyl bromide, 4-Hydroxyphenacyl bromide, SHP-1 Inhibitor II | ||
| PTP Inhibitor I is a cell-permeable, protein tyrosine phosphatase (PTP) inhibitor with Ki values of 43 and 42 μM for SHP-1(ΔSH2) and PTP1B, respectively. | ||
| M21439 | Poly-D-lysine hydrobromide (70,000-150,000) | Others |
| Poly-D-lysine HBr | ||
| Poly-D-lysine hydrobromide (70,000-150,000) | ||
| M27757 | GLP-1(7-36), amide TFA | GLP Receptor |
| Glucagon-like peptide-1 (GLP-1)(7-36), amide TFA; Human GLP-1 (7-36), amide TFA | ||
| GLP-1(7-36), amide TFA is a physiological incretin hormone that stimulates insulin secretion. | ||
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