About 22 results found for searched term "JC-1" (0.061 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M2259 | Biapenem | Antibiotic |
| L-627; LJC 10627; CLI 86815 | ||
| Biapenem is a new parenteral carbapenem antibacterial agent with a broad spectrum of in vitro antibacterial activity. | ||
| M4450 | Acteoside | PKC |
| Verbascoside; Kusaginin; TJC160 | ||
| Acteoside is isolated from Acanthus mollis, acts as an ATP-competitive inhibitor of PKC, with an IC50 of 25 µM, and has antitumor, anti-inflammatory and antineuropathic pain activity. | ||
| M8301 | MJC13 | Others |
| MJC13 inhibits the positive regulation of androgen receptor (AR) signaling by the cochaperone protein FKBP52. | ||
| M9724 | JC-1 | Fluorescent Dye |
| CBIC2; NK 1420 | ||
| Jc-1 (Mitochondrial membrane potential probe) is a fluorescent lipophilic carbonyl cyanine dye used to measure mitochondrial membrane potential. In normal mitochondria, JC-1 aggregates in the mitochondrial matrix to form a polymer, which emits strong red fluorescence (Ex=585 nm, Em=590 nm); When the mitochondrial membrane potential is low, JC-1 cannot aggregate in the matrix of mitochondria and produce green fluorescence (ex=510 nm, em= 527 nm). | ||
| M10454 | JC-1 Mitochondrial Membrane Potential Assay Kit | Fluorescent Dye |
| JC-1 Mitochondrial Membrane Potential Assay Kit is a kit that uses JC-1 as a fluorescent probe to quickly and sensitively detect the transmembrane potential difference of tissues, cells or purified mitochondria. It can be used for early apoptosis detection. | ||
| M10838 | JC124 | NLR |
| JC124 IS A SPECIFIC INHIBITOR OF THE NLRP3 INFLAMMASOME. JC124 HAS ANTI-INFLAMMATORY AND NEUROPROTECTIVE EFFECTS. | ||
| M10839 | JC-171 | NLR |
| JC-171 is a selective inhibitor of NLRP3 inflammasomes that inhibits the release of IL-1β by macrophages induced by LPS/ATP IC50 The value is 8.45 μM. | ||
| M11263 | HJC0197 | Ras |
| HJC0197 is a potent antagonist of Epac1 (the exchange protein directly activated by cAMP 1) and Epac2 (IC50=5.9 μM for Epac2). HJC0197 selectively blocked camp-induced Epac activation. HJC0197 inhibited epAC1-mediated RAP1-GDP exchange activity in the presence of isoconcentration of cAMP. | ||
| M13349 | Tebipenem | Antibiotic |
| LJC 11036 | ||
| Tebipenem, the first oral carbapenem antibiotic, inhibits both gram-positive and gram-negative bacteria, but has no effect on Pseudomonas aeruginosa. | ||
| M20625 | HJC0152 | STAT |
| HJC0152 is a signal transducer and activator of transcription 3 (STAT3) inhibitor with remarkably improved aqueous solubility. | ||
| M28084 | JCP174 | Elastase |
| JCP174 is an inhibitor of palmitoyl protein thioesterase-1 (TgPPT1), a depalmitoylase in the parasite T. gondii. JCP174 is also an inhibitor of porcine pancreatic elastase and human leukocyte elastase. | ||
| M42111 | HJC0416 | STAT |
| HJC0416 is a potent and orally active STAT3 inhibitor. | ||
| M49667 | HJC0149 | STAT |
| HJC0149 is a potent and orally active inhibitor of signal transducer and activator of transcription 3 (STAT3). | ||
| M49668 | HJC0416 hydrochloride | STAT |
| HJC0416 hydrochloride is a potent and orally active STAT3 inhibitor with an enhanced anticancer profile than Stattic. | ||
| M55305 | HJC0123 | STAT |
| HJC-0123 | ||
| HJC0123 is a novel STAT3 inhibitor that suppresses the fibrogenic properties of HSCs. HJC0123 reduced the phosphorylation, nuclear translocation, and transcriptional activity of STAT3. HJC0123 treatment resulted in the inhibition of HSCs proliferation at submicromolar concentrations. It decreased the expression of STAT3-regulated proteins, induced cell cycle arrest, promoted apoptosis and downregulated SOCS3. | ||
| M59196 | JC2-11 | NLR |
| JC2-11 is an inhibitor of inflammatory corpuscles. JC2-11 inhibits domain-containing protein NLRC 4, absent in melanoma 2 (AIM 2) and non-canonical (NC) inflammatory corpuscles. JC2-11 reduces the secretion of caspase-1 (p20), the cleavage of gasdermin D (GSDMD), and the releases of IL-1β and lactate dehydrogenases (LDH). | ||
| M59113 | JC-10 | Fluorescent Dye |
| JC-10 is an ideal fluorescent probe widely used to detect mitochondrial membrane potential △Ψm. Can detect cell, tissue or purified mitochondrial membrane potential. When the mitochondrial membrane potential is high, JC-10 aggregates in the matrix of the mitochondria to form a polymer, which can produce red fluorescence; when the mitochondrial membrane potential is low, JC-10 cannot accumulate in the matrix of the mitochondria, at this time JC- 10 is a monomer, which can produce green fluorescence. In this way, it is very convenient to detect the change of mitochondrial membrane potential through the change of fluorescence color. | ||
| M59890 | DNAJC17 Human Pre-designed siRNA Set | siRNA |
| DnaJ heat shock protein family (Hsp40) member C17 | ||
| Human DNAJC17 Pre-designed siRNA Set contains three designed siRNAs for DNAJC17 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control. Gene ID: 55192 | ||
| M60884 | Dnajc19 Human Pre-designed siRNA Set | siRNA |
| DnaJ heat shock protein family (Hsp40) member C19 | ||
| Human Dnajc19 Pre-designed siRNA Set contains three designed siRNAs for Dnajc19 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control. Gene ID: 131118 | ||
| M61550 | DNAJC15 Human Pre-designed siRNA Set | siRNA |
| DnaJ heat shock protein family (Hsp40) member C15 | ||
| Human DNAJC15 Pre-designed siRNA Set contains three designed siRNAs for DNAJC15 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control. Gene ID: 29103 | ||
| M62399 | DNAJC12 Human Pre-designed siRNA Set | siRNA |
| DnaJ heat shock protein family (Hsp40) member C12 | ||
| Human DNAJC12 Pre-designed siRNA Set contains three designed siRNAs for DNAJC12 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control. Gene ID: 56521 | ||
| M64593 | DNAJC11 Human Pre-designed siRNA Set | siRNA |
| DnaJ heat shock protein family (Hsp40) member C11 | ||
| Human DNAJC11 Pre-designed siRNA Set contains three designed siRNAs for DNAJC11 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control. Gene ID: 55735 | ||
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