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JC-1

Cat. No. M9724

All AbMole products are for research use only, cannot be used for human consumption.

JC-1 Structure
Synonym:

CBIC2; NK 1420

Size Price Availability Quantity
1mg USD 63  USD63 In stock
2mg USD 100  USD100 In stock
5mg USD 190  USD190 In stock
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Quality Control & Documentation
Biological Activity

Jc-1 (Mitochondrial membrane potential probe) is a fluorescent lipophilic carbonyl cyanine dye used to measure mitochondrial membrane potential. The maximum excitation/emission wavelength is 515nm/529nm (590nm), and green fluorescence is emitted. Used to observe mitochondria, stored at room temperature, away from light. Jc-1 should be redissolved in high-quality freshly opened DMSO (1 mg/mL). After redissolution, it should be stored at -20°C; Avoid freeze-thaw.

Product Citations
Chemical Information
Molecular Weight 652.23
Formula C25H27Cl4IN4
CAS Number 3520-43-2
Solubility (25°C) DMSO ≥ 10 mg/mL
Storage -20°C, protect from light, dry, sealed
References

[1] A Perelman, et al. Cell Death Dis. JC-1: alternative excitation wavelengths facilitate mitochondrial membrane potential cytometry

[2] Vera C Keil, et al. Pflugers Arch. Ratiometric high-resolution imaging of JC-1 fluorescence reveals the subcellular heterogeneity of astrocytic mitochondria

[3] Jung-Ho Lee, et al. Biochem J. Real-time analysis of amyloid fibril formation of alpha-synuclein using a fibrillation-state-specific fluorescent probe of JC-1

[4] S Salvioli, et al. FEBS Lett. JC-1, but not DiOC6(3) or rhodamine 123, is a reliable fluorescent probe to assess delta psi changes in intact cells: implications for studies on mitochondrial functionality during apoptosis

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Keywords: JC-1, CBIC2; NK 1420 supplier, Fluorescent Dye, inhibitors, activators

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