About 30 results found for searched term "Deoxycholic acid" (0.052 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M11303 | Glycodeoxycholic Acid | Metabolite/Endogenous Metabolite |
| Glycodeoxycholic Acid is an endogenous metabolite. Glycodeoxycholic Acid induces hepatocyte necrosis and autophagy in patients with obstructive cholestasis. | ||
| M2507 | Chenodeoxycholic acid | Farnesoid X Receptor |
| CDCA; Chenodiol | ||
| Chenodeoxycholic acid is an epimer of ursodeoxycholic acid, which inhibits the production of cholesterol in the liver and absorption in the intestines. | ||
| M3775 | Obeticholic Acid (INT-747) | Farnesoid X Receptor |
| 6-ECDCA; UNII-0462Z4S4OZ; OCA; 6-Ethylchenodeoxycholic acid | ||
| Obeticholic Acid (INT-747) is a potent, orally active, selective farnesoid X receptor (FXR) agonist with an EC50 of 99 nM.May be used in studies related to non-alcoholic steatohepatitis (NASH). | ||
| M5158 | Tauroursodeoxycholic acid (Ursodoxicoltaurine) | ERK |
| TUDCA; Ursodoxicoltaurine; Ursodeoxycholyltaurine; Tauroursodeoxycholate; UR 906; Taurursodiol | ||
| Tauroursodeoxycholic acid (Ursodoxicoltaurine) is an endoplasmic reticulum stress inhibitor. It can significantly reduce the expression of apoptotic molecules such as caspase-3 and caspase-12. Tauroursodeoxycholate also suppresses ERK. It is a taurine conjugate of usodeoxycholic acid. | ||
| M11152 | Deoxycholic acid sodium salt | GPCR19/TGR5 |
| Sodium deoxycholate | ||
| Deoxycholic acid sodium salt is a bile acid and a by-product of intestinal metabolism, Deoxycholic acid sodium salt can activate the G protein-coupled bile acid receptor TGR5. | ||
| M5340 | Tauroursodeoxycholate Sodium | ERK |
| TUDCA; Sodium tauroursodeoxycholate; Tauroursodeoxycholic acid sodium salt | ||
| Sodium Tauroursodeoxycholate (TUDC) is a water soluble bile salt, used for the treatment of gallstones and liver cirrhosis. | ||
| M5563 | Deoxycholic acid | Others |
| Deoxycholate, Desoxycholic acid, Cholerebic, Cholorebic | ||
| Deoxycholic acid is a cytolytic agent. The physiologic effect of deoxycholic acid is by means of decreased cell membrane integrity. | ||
| M11301 | Glycohyodeoxycholic acid | Metabolite/Endogenous Metabolite |
| Glycohyodeoxycholic acid is the main metabolite of Hyodeoxycholic acid in human body, which can prevent the formation of gallstones. | ||
| M6047 | Ursodiol | Animal Modeling |
| UDCA；Ursodeoxycholic acid; UDCS；Ursodeoxycholate; Ursodiol | ||
| Ursodiol reduces cholesterol absorption and is used to dissolve (cholesterol) gallstones with an IC50 of 0.22 μM. Ursodeoxycholic acid (UDCA), which reduces FXR and closes the ACE2 channel. It can be used to construct animal models of cholelithiasis. | ||
| M9408 | Glycochenodeoxycholic acid | Metabolite/Endogenous Metabolite |
| Chenodeoxycholylglycine | ||
| Glycochenodeoxycholic acid (Chenodeoxycholylglycine) is a bile acid formed in the liver from chenodeoxycholate and glycine. | ||
| M9409 | Glycoursodeoxycholic acid | Metabolite/Endogenous Metabolite |
| Ursodeoxycholylglycine | ||
| Glycoursodeoxycholic acid, a acyl glycine and a bile acid-glycine conjugate, is a metabolite of ursodeoxycholic acid. | ||
| M11050 | Tauroursodeoxycholate dihydrate | ERK |
| Tauroursodeoxycholic acid dihydrate | ||
| Tauroursodeoxycholate (Tauroursodeoxycholic acid; TDUCA) dihydrate is an endoplasmic reticulum stress inhibitor. Tauroursodeoxycholate significantly reduces the expression of apoptotic molecules such as caspase-3 and caspase-12. Tauroursodeoxycholate also suppresses ERK. | ||
| M11178 | Taurochenodeoxycholic acid | Apoptosis |
| Taurochenodeoxycholate, TCDCA, 12-Deoxycholyltaurine, Chenodeoxycholyltaurine, Chenyltaurine | ||
| Taurochenodeoxycholic acid (12-Deoxycholyltaurine) is one of the main bioactive substances of animal bile acids. Taurochenodeoxycholic acid induces apoptosis (apoptosis) and has a pronounced anti-inflammatory and immunomodulatory effect. | ||
| M11414 | Hyodeoxycholic acid | Metabolite/Endogenous Metabolite |
| HDCA; NSC 60672 | ||
| Hyodeoxycholic acid is a secondary bile acid formed by intestinal flora in the small intestine and is an agonist of TGR5 (GPCR19). In CHO cells, the EC50 value is 31.6 µM. | ||
| M13346 | Taurodeoxycholate sodium salt | Metabolite/Endogenous Metabolite |
| Sodium Taurodeoxycholate; Taurodeoxycholic acid sodium salt | ||
| Taurodeoxycholate sodium salt is a bile salt formed in the liver by conjugation of deoxycholate with taurine, usually as the sodium salt. It is used as a cholagogue and choleretic, also industrially as a fat emulsifier. | ||
| M13985 | Ursodeoxycholic acid sodium | GPCR19/TGR5 |
| Ursodeoxycholate sodium; Ursodiol sodium; UCDA sodium | ||
| Ursodeoxycholic acid (Ursodeoxycholate) sodium is a secondary bile acid issued from the transformation of (cheno)deoxycholic acid by intestinal bacteria, acting as a key regulator of the intestinal barrier integrity and essential for lipid metabolism. | ||
| M18077 | Chenodeoxycholic acid methyl ester | Others |
| Chenodeoxycholic acid methyl ester | ||
| M21462 | 24-Norursodeoxycholic acid | Others |
| nor-UDCA | ||
| 24 norursodeoxycholic acid (nor UDCA) is a C23 homologue of UDCA with shortened side chain, which has effective anti cholestasis, anti-inflammatory and anti fibrosis properties. | ||
| M27695 | Hyodeoxycholic acid sodium | Others |
| HDCA sodium | ||
| Hyodeoxycholic acid sodium salt is a biochemical reagent that can be used as a biological material or organic compound for life science related research. | ||
| M30219 | 12-Ketodeoxycholic acid | Metabolite/Endogenous Metabolite |
| 12-Ketodeoxycholic acid is a bile acid, metabolite from kidney. 12-Ketodeoxycholic acid can be a detectable marker for evidence of kidney injury. | ||
| M39096 | Murideoxycholic acid | Metabolite/Endogenous Metabolite |
| Murideoxycholic acid is a 6 beta-hydroxylated bile acid. | ||
| M42387 | Chenodeoxycholic acid 3-sulfate | Metabolite/Endogenous Metabolite |
| Chenodeoxycholic acid 3-sulfate is a bile acid. | ||
| M45007 | Taurochenodeoxycholic acid sodium | Apoptosis |
| Sodium taurochenodeoxycholate | ||
| Taurochenodeoxycholic acid (12-Deoxycholyltaurine) sodium is one of the main bioactive substances of animals' bile acid. | ||
| M55039 | Ursocholic acid | Metabolite/Endogenous Metabolite |
| Ursodeoxycholic acid EP Impurity D | ||
| Ursocholic acid is a bile acid found predominantly in bile of mammals, which can be transformed into deoxycholic acid by the intestinal microflora in mice. | ||
| M55699 | Taurohyodeoxycholic acid sodium | IL Receptor/Related |
| THDCA sodium | ||
| Taurohyodeoxycholic acid (THDCA) sodium prevents apoptosis by blocking a calcium-mediated apoptotic pathway as well as caspase-12 activation. Taurohyodeoxycholic acid sodium can also reduce the activity and expression of myeloperoxidase TNF-α and IL-6, as well as colonic damage in TNBS-induced ulcerative colitis mouse model. | ||
| M57270 | 7-keto-Deoxycholic acid | Others |
| 7-keto-Deoxycholic acid is a metabolite of bile acids in Clostridium absonum. | ||
| M57260 | Nordeoxycholic acid | Others |
| Nordeoxycholic acid is a 23-carbon bile acid. | ||
| M56938 | Isochenodeoxycholic acid | Others |
| Isochenodeoxycholic acid (isoCDCA) is a human fecal bile acid. | ||
| M57707 | Chenodeoxycholic Acid 24-Acyl-β-D-Glucuronide | Others |
| Chenodeoxycholic Acid 24-Acyl-β-D-Glucuronide | ||
| M58378 | Taurodeoxycholic acid | Metabolite/Endogenous Metabolite |
| Taurodeoxycholic acid, a bile acid, stabilizes the mitochondrial membrane, decreases free radical formation. Taurodeoxycholic acid inhibits apoptosis by blocking a calcium-mediated apoptotic pathway as well as caspase-12 activation. | ||
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