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24-Norursodeoxycholic acid

Cat. No. M21462

All AbMole products are for research use only, cannot be used for human consumption.

24-Norursodeoxycholic acid  Structure
Synonym:

nor-UDCA

Size Price Availability Quantity
5mg USD 65  USD65 In stock
10mg USD 100  USD100 In stock
25mg USD 160  USD160 In stock
50mg USD 255  USD255 In stock
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Quality Control & Documentation
Biological Activity

24 norursodeoxycholic acid (nor UDCA) is a C23 homologue of UDCA with shortened side chain, which has effective anti cholestasis, anti-inflammatory and anti fibrosis properties.

Chemical Information
Molecular Weight 378.55
Formula C23H38O4
CAS Number 99697-24-2
Solubility (25°C) DMSO ≥ 40 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Alix Bruneau, et al. Curr Opin Gastroenterol. Macrophages in cholangiopathies

[2] Ci Zhu, et al. J Hepatol. 24-Norursodeoxycholic acid reshapes immunometabolism in CD8+ T cells and alleviates hepatic inflammation

[3] Maria Reich, et al. J Hepatol. Downregulation of TGR5 (GPBAR1) in biliary epithelial cells contributes to the pathogenesis of sclerosing cholangitis

[4] Peter Fickert, et al. Gastroenterology. 24-norUrsodeoxycholic acid is superior to ursodeoxycholic acid in the treatment of sclerosing cholangitis in Mdr2 (Abcb4) knockout mice

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Keywords: 24-Norursodeoxycholic acid , nor-UDCA supplier, inhibitors, activators

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