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Obeticholic Acid (INT-747) is a potent, orally active, selective farnesoid X receptor (FXR) agonist with an EC50 of 99 nM.May be used in studies related to non-alcoholic steatohepatitis (NASH).
Molecular Weight | 420.63 |
Formula | C26H44O4 |
CAS Number | 459789-99-2 |
Solubility (25°C) | DMSO 60 mg/mL |
Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[2] Fiorucci S, et al. Expert Opin Ther Targets. Targeting FXR in cholestasis: hype or hope.
Related Farnesoid X Receptor Products |
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Linafexor
Linafexor is a bile acid receptor (FXR) agonist that may be used in studies related to cholangitis and non-alcoholic steatohepatitis. |
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