About 30 results found for searched term "CY2" (0.012 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M1974 | Roscovitine | CDK |
| Seliciclib; CYC202; (R)-Roscovitine | ||
| Roscovitine (Seliciclib) is a potent and selective inhibitor of the cyclin-dependent kinases cdc2, cdk2 and cdk5, with IC50 values of 0.2 μM, 0.65 μM, and 0.7 μM for CDK5, Cdc2, and CDK2, respectively. | ||
| M2052 | Decitabine | DNA Methyltransferase |
| 5-Aza-2'-deoxycytidine; NSC 127716; 5-Aza-dC; 5-AZA-CdR | ||
| Decitabine (5-Aza-2'-deoxycytidine) is a potent inhibitor of DNA methylation for the treatment of myelodysplastic syndromes. | ||
| M2123 | Rocilinostat | HDAC |
| ACY-1215; Ricolinostat | ||
| Rocilinostat (ACY-1215) is an HDAC6-selective inhibitor with IC50 of 5 nM. | ||
| M2546 | CYM-5442 | S1P Receptor |
| CYM-5442 is a potent and selective S1P1 agonist with EC50 of 1.35 nM. CYM5442 activates S1P1-dependent p42/p44-MAPK phosphorylation. CYM5442 can easily penetrate the central nervous system (CNS). | ||
| M2547 | Cyromazine | Metabolite/Endogenous Metabolite |
| Cyromazin; CGA-72662 | ||
| Cyromazine is a triazine insect growth regulator used as an insecticide and an acaricide. | ||
| M3347 | Zalcitabine | Reverse Transcriptase |
| ddC; Dideoxycytidine; 2',3'-Dideoxycytidine | ||
| Zalcitabine is a nucleoside analog HIV reverse transcriptase inhibitor (NARTI). | ||
| M4518 | Procyanidin-B2 | NLR |
| Proanthocyanidin B2 | ||
| Procyanidin B2 is a natural flavonoid with anti-tumor and anti-oxidation effects. Procyanidin B2 inhibited NLRP3 inflammasome activation via suppression of AP-1 pathway. | ||
| M4907 | Doxycycline Hyclate | MMP |
| Doxycycline hydrochloride hemiethanolate hemihydrate; WC2031 | ||
| Doxycycline is a member of the tetracycline antibiotics group, and is commonly used to treat a variety of infections. | ||
| M4923 | Cyanoacetohydrazide | Antibiotic |
| Cyanoacetic hydrazide; 2-Cyanoacetohydrazide | ||
| Cyanoacetohydrazide is an anti-tuberculous compound. | ||
| M5259 | Citarinostat | HDAC |
| ACY-241 | ||
| Citarinostat (ACY-241) is an orally available selective HDAC6 inhibitor with IC50 of 2.6 nM and 46 nM for HDAC6 and HDAC3, respectively. It has 13 to 18-fold selectivity towards HDAC6 in comparison to HDAC1-3. | ||
| M5479 | Carsalam | Others |
| Carbonylsalicylamide; 2H-1,3-Benzoxazine-2,4(3H)-dione | ||
| Carsalam (Carbonylsalicylamide) is a non-steroidal anti-inflammatory compound. | ||
| M5619 | Eptifibatide | Integrin |
| MPA-HAR-Gly-Asp-Trp-Pro-Cys-NH2; {MPA}{HAR}GDWPC-NH2 | ||
| Eptifibatide is an antiplatelet drug of the glycoprotein IIb/IIIa inhibitor class. | ||
| M5651 | Flucytosine | DNA/RNA Synthesis |
| 5-Fluorocytosine; NSC 103805; Ro 2-9915 | ||
| Flucytosine (5-Fluorocytosine, 5-FC, Ancobon), a fluorinated pyrimidine analogue, is an antifungal drug. | ||
| M5829 | Octisalate | Others |
| Octyl salicylate; 2-Ethylhexyl salicylate | ||
| Octisalate is an organic compound used as an ingredient in sunscreens and cosmetics to absorb the full range of UVB rays from the sun. | ||
| M6026 | Tranylcypromine (2-PCPA) HCl | Monoamine Oxidase |
| SKF-385 HCl; Trans 2-Phenylcyclopropylamine Hydrochloride | ||
| Tranylcypromine HCl is a monoamine oxidase inhibitor, which inhibits CYP2A6 with Ki of 0.08 μM and 0.2 μM in cDNA-expressing microsomes and Human Liver Microsomes, respectively. Tranylcypromine hydrochloride inhibits LSD1, MAO A and MAO B with IC50s of 20.7, 2.3 and 0.95 μM, respectively. | ||
| M6289 | Erythromycin cyclocarbonate | Antibiotic |
| Erythromycin cyclic carbonate; Erythromycin A 11,12-carbonate | ||
| Erythromycin Cyclocarbonate, derivative of Erythromycin, inhibits protein synthesis of bacteria by binding to the 50S ribosome. | ||
| M6642 | CYM 50260 | S1P Receptor |
| CYM 50260 is a potent and selective S1P4 agonist. | ||
| M6643 | CYM 5520 | S1P Receptor |
| CYM 5520 is a selective S1P2 allosteric agonist. | ||
| M6660 | Decynium 22 | Others |
| Decynium 22 is a pMAT inhibitor. | ||
| M25610 | (E)-Cyclooct-2-en-1-yl (4-nitrophenyl) carbonate | Others |
| (E)-Cyclooct-2-en-1-yl (4-nitrophenyl) carbonate | ||
| M9157 | 2-Phenylethyl isothiocyanate | Antifungal |
| Isothiocyanic Acid 2-Phenylethyl Ester;2-PE ITC; PEITC | ||
| 2-Phenylethyl isothiocyanate is a natural product found in bean sprouts and cruciferous vegetables, and is also an effective antifungal agent, significantly inhibiting spore germination and mycelial growth of Aspergillus intermedius. In addition, 2-Phenylethyl isothiocyanate induces autophagy and inhibits the growth of various tumor cells. | ||
| M10233 | ((Cys31,Nva34)-Neuropeptide Y (27-36))2 | Neuropeptide Receptor |
| BWX 46 | ||
| ((Cys31,Nva34)-Neuropeptide Y (27-36))2, also called BWX 46, is a neuropeptide Y (NPY) Y5 receptor selective agonist. | ||
| M10240 | CTOP TFA | Opioid Receptor |
| D-PHE-CYS-TYR-D-TRP-ORN-THR-PEN-THR-NH2 | ||
| CTOP TFA is a peptide that acts as a potent and selective μ opioid receptor antagonist, with Ki values of 0.96 and >10,000 nM for μ and δ receptors, respectively. | ||
| M10353 | Recombinant Human FGF-10/KGF-2 (E. coli) | Cytokines and Growth Factors |
| FGFA, Keratinocyte growth factor-2 | ||
| Recombinant human fibroblast growth factor-10 (FGF-10) is a mitogen produced mainly by lung mesenchymal stem cells. Fgf-10 belongs to the heparin-binding FGF-family, also known as keratinocyte growth factor-2 (KGF-2). It has homology with KGF and receptor with FGFR2-IIIb. Expressed by Escherichia coli. | ||
| M11205 | Hexanoic acid,2,6-diisocyanato-, 2-isocyanatoethyl ester | Others |
| 2,6-diisocyanato-hexanoicaci2-isocyanatoethylester | ||
| M11485 | Recombinant Mouse GM-CSF Protein (E. coli) | Cytokines and Growth Factors |
| Granulocyte Macrophage Colony Stimulating Factor; CSF-2; MGI-1GM | ||
| Recombinant GM-CSF Protein is a growth factor that can support the in vitro colony formation of granulocyte-macrophage progenitors. GM-CSF is produced by a number of different cell types, including activated T cells, B cells, macrophages, mast cells, endothelial cells, and fibroblasts, in response to cytokine of immune and inflammatory. ED50 < 5.0 pg/ mL, measured in cell proliferation assay of mouse FDC-P1 cells, corresponding specific activity > 2.0 × 108 units/mg. | ||
| M11489 | Recombinant Human MCP-1/CCL2 (E. coli) | Cytokines and Growth Factors |
| MCAF; JE; Monocyte Chemotactic Protein-1; CCL2; MCP1 | ||
| The EC50 value of human MCP-1/CCL2 on Ca2+ mobilization assay in CHO-K1/Gα15/hCCR2 cells (human Gα15 and human CCR2 stably expressed in CHO-K1 cells) is less than 1.0 μg/ml. Accession # : P13500. | ||
| M15023 | Recombinant Human MCP-2/CCL8 (E. coli) | Cytokines and Growth Factors |
| Monocyte Chemoattractant Protein-2; HC14; SCYA8 | ||
| McP-2, a member of the chemokine family, is a group of 70-80 residues with significant sequence similarity. Protein structure: McP-2 (GLN24-PRO99), Accession # P80075. | ||
| M15041 | Recombinant Human MEC/CCL28 (E. coli) | Cytokines and Growth Factors |
| Chemokine (C-C motif) ligand 28; CCL-28; SCYA28 | ||
| CCL28 (CC chemokine ligand 28), a novel CC chemokine, was identified by TBLASTN search using the human Genome System (HGS) and Genbank dbEst databases using a consistent sequence of human chemokines. Protein structure: CCL28 (Ser20-Tyr127), Accession # ：Q9NRJ3. | ||
| M14561 | Recombinant Human MIP-5/CCL15 Protein (E. coli, aa 22-113, C-His) | Cytokines and Growth Factors |
| SCYA15; HCC-2; NCC-3 | ||
| Chemokine ligand 15 (CCL15), also known as leukotactin-1, MIP5, MIP1 and HCC-2, is a small cytokine belonging to the C-C chemokine family. CCL15 is prevantly expressed in liver, small intestine, colon, and in certain leukocytes and macrophages of the lung. | ||
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