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CYM-5442 hydrochloride

Cat. No. M2546
CYM-5442 hydrochloride Structure
Size Price Availability Quantity
5mg USD 126  USD140 In stock
10mg USD 198  USD220 In stock
50mg USD 720  USD800 In stock
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Quality Control
  • Current batch:
  • Purity >98%
  • COA
  • MSDS
Biological Activity

CYM-5442 is a potent and selective S1P1 agonist with EC50 of 1.35 nM.

Conversion of different model animals based on BSA (Value based on data from FDA Draft Guidelines)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.

Chemical Information
Molecular Weight 445.94
Formula C23H27N3O4.HCl
CAS Number 1094042-01-9
Purity >98%
Solubility DMSO
Storage at -20°C
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  Catalog
Abmole Inhibitor Catalog 2017




Keywords: CYM-5442 hydrochloride supplier, S1P Receptor, inhibitors

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