| Cat.No. | Name | Information |
|---|---|---|
| M2562 | ZCL278 | ZCL278 is a selective Cdc42 GTPase inhibitor with Kd of 11.4 μM. |
| M6282 | NSC 23766 | NSC 23766 is an inhibitor of Rac GTPase targeting Rac activation by guanine nucleotide exchange factors (GEFs) with IC50 of ~50 μM in a cell-free assay; does not inhibit the closely related targets, Cdc42 or RhoA. |
| M9356 | AMG-510 (Sotorasib) | AMG-510 (Sotorasib) is a potent KRAS G12C covalent inhibitor. |
| M9428 | MRTX849 (Adagrasib) | MRTX849 (Adagrasib) is a potent, highly selective, oral available KRAS G12C inhibitor. |
| M45161 | ARS-3248 | ARS-3248 is a novel KRAS G12C inhibitor. |
| M45160 | LY3499446 | LY3499446 is a KRAS G12C covalent inhibitor for studies related to non-small cell lung cancer (NSCLC). |
| M45053 | ACBI3 | ACBI3 is a selective and potent pan-KRAS degrader. |
| M43844 | MK-1084 | MK-1084 is a KRAS G12C inhibitor that can be used in studies related to solid tumors. |
| M41938 | CFL-120 | CFL-120 is a potent KRasG12C inhibitor. |
| M41937 | CFL-137 | CFL-137 is a potent KRasG12C inhibitor. |
| M41936 | Oligomycin D | Oligomycin D (Rutamycin A) is an antibiotic. |
| M41935 | KRAS inhibitor-22 | KRAS inhibitor-22 is a potent inhibitor of K-Ras. |
| M41934 | pan-KRAS-IN-3 | pan-KRAS-IN-3 is a pan-KRAS inhibitor. |
| M41933 | KRASG12C IN-2 | KRASG12C IN-2 is an orally active KRASG12C inhibitor. |
| M41932 | Rac1-IN-3 | Rac1-IN-3 is a Rac1 inhibitor with an IC50 of 46.1 μM. |
| M41931 | PAT-IN-2 | PAT-IN-2 is a protein acyl transferases (PAT) inhibitor. |
| M41930 | PAT-IN-1 | PAT-IN-1 is a protein acyl transferases (PAT) inhibitor. |
| M41929 | RMC-4998 | RMC-4998 is a molecular glue compound with good antitumor activity. |
| M41928 | SCH54292 | SCH54292 is a potent Ras-GEF interaction inhibitor with IC50 of 0.7 μM. |
| M41927 | KRAS G12C inhibitor 58 | KRAS G12C inhibitor 58 is a KRAS G12C inhibitor, used in cancer research. |
| M41926 | SOS1-IN-16 | SOS1-IN-16 is a selective inhibitor of SOS1 with an IC50 of 7.2 nM. |
| M41925 | PROTAC KRAS G12C degrader-3 | PROTAC KRAS G12C degrader-3 is a potent KRAS G12C degrader for cancer research. |
| M41924 | pan-KRAS-IN-4 | pan-KRAS-IN-4 is a potent inhibitor of KRAS with IC50s of 0.37 nM (Kras G12C), 0.19 nM (Kras G12V), respectively. |
| M41923 | TH-Z816 | TH-Z816 is a reversible inhibitor againstKRAS(G12D)mutation with an IC50 value of 14 μM, which can be used in cancer research. |
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