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Salirasib

Cat. No. M5946

All AbMole products are for research use only, cannot be used for human consumption.

Salirasib Structure
Synonym:

S-Farnesylthiosalicylic acid; Farnesyl Thiosalicylic Acid; FTS

Size Price Availability Quantity
5mg USD 30  USD30 In stock
10mg USD 50  USD50 In stock
25mg USD 110  USD110 In stock
50mg USD 175  USD175 In stock
100mg USD 220  USD220 In stock
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Quality Control & Documentation
Biological Activity

Salirasib is a potent competitive prenylated protein methyltransferase (PPMTase) inhibitor with Ki of 2.6 μM, which inhibits Ras methylation. Phase 2.

Chemical Information
Molecular Weight 358.54
Formula C22H30O2S
CAS Number 162520-00-5
Solubility (25°C) 10 mM in DMSO
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Charette N, et al. Cell Death Dis. Salirasib sensitizes hepatocarcinoma cells to TRAIL-induced apoptosis through DR5 and survivin-dependent mechanisms.

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  Catalog
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Keywords: Salirasib, S-Farnesylthiosalicylic acid; Farnesyl Thiosalicylic Acid; FTS supplier, Ras, inhibitors, activators

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