Delivery vehicle / Excipient
| Cat.No. | Name | Information |
|---|---|---|
| M56706 | Lipid 5 | Lipid 5 is an amino lipid that affords efficient mRNA delivery in rodent and primate models. |
| M49825 | 1,5-Dihexadecyl N-(3-carboxy-1-oxopropyl)-L-glutamate | 1,5-Dihexadecyl N-(3-carboxy-1-oxopropyl)-L-glutamate is a lipid that can be used in the synthesis of phospholipid vesicles to improve protein encapsulation. |
| M49811 | Dimethyldioctadecylammonium bromide | Dimethyldioctadecylammonium bromide is a synthetic cationic lipid consisting of a positively charged ammonium head group and two long hydrophobic tails that can be used to form liposomes and other lipid-based nanoparticles, which are commonly used in studies related to gene delivery and vaccine development. |
| M49808 | 306Oi10 | 306Oi10 is a branched ionizable liposome that can be used to construct lipid nanoparticles (LNPs) for messenger RNA delivery. |
| M49807 | TCL053 | TCL053 is an ionizable lipid that can be used to efficiently introduce active ingredients, especially nucleic acids, into cells. In addition, TCL053 is capable of forming lipid nanoparticles (LNPs) with dipalmitoylphosphatidylcholine (DPPC), polyethylene glycol dimyristoylglycerol (PEG-DMG), and cholesterol, which can be used to deliver Cas9 mRNA and sgRNA into skeletal muscle. |
| M49806 | Genevant CL1 | Genevant CL1 is an ionizable cationic lipid (lipid 10, pKa=6.3) that can be used in studies related to mRNA lipid nanoparticle (LNP) vaccine delivery. |
| M49805 | CCD Lipid01 | CCD Lipid01 is a cationic lipid that can be used to deliver bioactive agents to cells and tissues. |
| M49801 | 5A2-SC8 | 5A2-SC8 is a degradable lipid-like compound (ester-based dendrimer) that can be used for small RNA delivery. |
| M49796 | DSPE-PEG2K-NHS | DSPE-PEG2K-NHS is a PEG-modified phospholipid derivative that can be used to prepare liposomes for the delivery of DNA or mRNA vaccines. |
| M49795 | ALC-0159 | ALC-0159 is a lipid conjugate of polyethylene glycol that can be used as an excipient for vaccines. |
| M49793 | DPPG sodium | DPPG sodium is a phospholipid containing long chain (16:0) palmitic acid inserted in the sn-1 and sn-2 positions.DPPG sodium can be used to prepare micelles, liposomes and other types of artificial membranes. |
| M49396 | ATX-0114 | ATX-0114 is an ionizable cationic lipid. |
| M25559 | DOPS sodium | DOPS sodium is a ubstitute for Phosphoserine/phosphatidylserine. DOPS can be used in lipid mixtures with DOPC and DOPE as effective nontoxic and nonviral DNA vectors, and in lipid mixtures to mimic platelet membranes for coagulation studies. |
| M22503 | A18-Iso5-2DC18 | A18-Iso5-2DC18 could not only deliver mRNA vaccines robustly but also activate the stimulator of interferon genes (STING) pathway. A18-Iso5-2DC18 is an alkylene ketone-derived. |
| M22502 | ATX-100 | ATX-100 is a novel cationic lipid (pKa = 6.38). It has been used in the generation of lipid nanoparticles (LNPs) for the delivery of siRNA. |
| M22501 | SM-102 | ALC-0159 is a lipid conjugate of polyethylene glycol that can be used as an immunosuppressant SM-102 is an ionizable aminolipid with a terminal hydroxyl group in the head group, which reduces the hydration of the head group and improves hydrogen bonding interactions with nucleic acids, thus enhancing transfection.SM-102 can be used for the preparation of lipid nanoparticles (LNPs), as well as for the lipid nanoparticle delivery of |
| M22500 | ALC-0315 (Liquid) | ALC-0315 is an ionisable aminolipid that is responsible for mRNA compaction and aids mRNA cellular delivery and its cytoplasmic release through suspected endosomal destabilization. ALC-0315 can be used to form lipid nanoparticle (LNP) delivery vehicles. |
| M22499 | C12-200 | C12-200 is a benchmark ionizable cationic lipidoid along with helper lipids. C12-200 is commonly used for mRNA delivery. |
| M22498 | CKK-E12 (Liquid) | CKK-E12 is a ionizable lipid in combination with other lipids make up the lipid nanoparticles which are used to deliver RNA-based therapeutics. CKK-E12 was highly selective toward liver parenchymal cell in vivo. |
| M22435 | DLin-KC2-DMA | DLin-KC2-DMA is an ionisable cationic lipid (pKa≈6), produces significant siRNA-mediated gene silencing of GAPDH, when binds to lipid nanoparticles (LNP). |
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