Delivery vehicle / Excipient
| Cat.No. | Name | Information |
|---|---|---|
| M22498 | CKK-E12 (Liquid) | CKK-E12 is a ionizable lipid in combination with other lipids make up the lipid nanoparticles which are used to deliver RNA-based therapeutics. CKK-E12 was highly selective toward liver parenchymal cell in vivo. |
| M22435 | DLin-KC2-DMA | DLin-KC2-DMA is an ionisable cationic lipid (pKa≈6), produces significant siRNA-mediated gene silencing of GAPDH, when binds to lipid nanoparticles (LNP). |
| M14954 | DLinDMA | DLinDMA, a ionizable cationic lipid, is a key lipid component of stable nucleic acid lipid particles (SNALPs) as a benchmark. DLinDMA is used for siRNA delivery. |
| M13353 | Phosphatidylcholines,soya | Phosphatidylcholines, soya is a kind of extracted from soybean phosphatidyl choline, can be used for the preparation of liposomes. Has been shown to play important roles in many important areas, including maintenance of cellular structure, fat metabolism, memory, nerve signaling, acting as a precursor of important neurotransmitters, and liver health. Phosphatidylcholines, soya can be used as animal drug delivery carrier. |
| M9382 | DLin-MC3-DMA | DLin-MC3-DMA is the most potent cationic lipid that has been synthesized for lipid nanoparticles (LNPs) to deliver the siRNA. |
| M6680 | DLPC | DLPC is a lRH-1 agonist; regulates bile acid metabolism. |
| M4163 | β-Sitosterol | Replacing cholesterol in lipid nanoparticle (LNP) formulations with β-Sitosterol, a natural phytosterol, significantly improves mRNA delivery. |
| M56708 | DOBAQ | DOBAQ, a cationic lipid, is a pH-sensitive lipid. |
| M56707 | G-5758 | G-5758 is an orally available IRE1α inhibitor with an IC50 of 38 nM for XBP1s. |
| M49912 | Vaxfectin | Vaxfectin is a cationic lipid adjuvant for use in the study of plasmid DNA and protein-based vaccines. |
| M49896 | 98N12-5 | 98N12-5 is a novel ionizable lipid that can be used in studies related to siRNA delivery. |
| M49826 | YSK 05 | YSK 05 is a pH-sensitive cationic lipid with good gene silencing and hemolytic activity, overcomes inhibition of endosomal escape by polyethylene glycolization, and improves intracellular transport of non-viral vectors.YSK 05 is effective in enhancing siRNA delivery both in vitro and in vivo.YSK 05 is a pH-sensitive cationic lipid with good gene silencing and hemolytic activity. |
| M49824 | AA-T3A-C12 | AA-T3A-C12 is an anisamide ligand-bolus lipidoid (AA-lipidoid) that can be used to mediate bulk RNA delivery and transfection of activated fibroblasts. |
| M49820 | ZA3-Ep10 | ZA3-Ep10 is an amphipathic ionic lipid that synthesizes lipid nanoparticles for in vivo RNA delivery and non-viral CRISPR/Cas gene editing. |
| M49819 | N1,N3,N5-Tris(4-dodecylhexadecyl)benzene-1,3,5-tricarboxamide | N1,N3,N5-Tris(4-dodecylhexadecyl)benzene-1,3,5-tricarboxamide is an analog of TT3, an ionizable lipid-like material used for mRNA and CRISPR/Cas9 delivery. |
| M49818 | DLin-K-C3-DMA | DLin-K-C3-DMA is a cationic lipid that can be used for the synthesis of nucleic acid lipid particles. |
| M49816 | Lipid 29 | Lipid 29 is an ionizable amino lipid that can be used to prepare lipid nanoparticles. |
| M49815 | BAMEA-O16B | BAMEA-O16B is a lipid nanoparticle that binds disulfide bonds and can efficiently deliver Cas9 mRNA and sgRNA into cells while releasing RNA for genome editing in response to intracellular reducing environments.BAMEA-O16B can be used for gene editing research. |
| M49814 | NT1-014B | NT1-014B is an effective encapsulated NT1-like lipid with amphotericin B (AmB) that dopes NT-like lipids into BBB-impermeable lipid nanoparticles (LNPs), allowing the LNPs to pass through the BBB. |
| M49810 | FTT5 | FTT5 is an ionizable lipid that efficiently delivers long mRNAs in vivo. |
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