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DLinDMA

Cat. No. M14954

All AbMole products are for research use only, cannot be used for human consumption.

DLinDMA Structure
Size Price Availability Quantity
50mg USD 150  USD150 In stock
100mg USD 260  USD260 In stock
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Quality Control & Documentation
Biological Activity

DLinDMA, a ionizable cationic lipid, is a key lipid component of stable nucleic acid lipid particles (SNALPs) as a benchmark. DLinDMA is used for siRNA delivery.

Chemical Information
Molecular Weight 616.06
CAS Number 871258-12-7
Form Liquid
Solubility (25°C) Ethanol ≥ 90 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Hari Priya Vemana, et al. A novel gene therapy for neurodegenerative Lafora disease via EPM2A-loaded DLinDMA lipoplexes

[2] Paulo J C Lin, et al. Influence of cationic lipid composition on uptake and intracellular processing of lipid nanoparticle formulations of siRNA

[3] Genc Basha, et al. Influence of cationic lipid composition on gene silencing properties of lipid nanoparticle formulations of siRNA in antigen-presenting cells

[4] Sean C Semple, et al. Rational design of cationic lipids for siRNA delivery

[5] James Heyes, et al. Cationic lipid saturation influences intracellular delivery of encapsulated nucleic acids

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Keywords: DLinDMA supplier, Liposome, inhibitors, activators

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