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SM-102

Cat. No. M22501

All AbMole products are for research use only, cannot be used for human consumption.

SM-102 Structure
Synonym:

SM102

Size Price Availability Quantity
10mg USD 170  USD170 In stock
25mg USD 285  USD285 In stock
50mg USD 455  USD455 In stock
100mg USD 645  USD645 In stock
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Quality Control & Documentation
Biological Activity

ALC-0159 is a lipid conjugate of polyethylene glycol that can be used as an immunosuppressant SM-102 is an ionizable aminolipid with a terminal hydroxyl group in the head group, which reduces the hydration of the head group and improves hydrogen bonding interactions with nucleic acids, thus enhancing transfection.SM-102 can be used for the preparation of lipid nanoparticles (LNPs), as well as for the lipid nanoparticle delivery of

Chemical Information
Molecular Weight 710.17
Formula C44H87NO5
CAS Number 2089251-47-6
Form Liquid
Solubility (25°C) Ethanol 90 mg/mL
DMSO 90 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Kepan Chen, et al. Adv Funct Mater. mRNA Vaccines Against SARS-CoV-2 Variants Delivered by Lipid Nanoparticles Based on Novel Ionizable Lipids

[2] Sheng-Nan Wu, et al. Int J Mol Sci. Effective Perturbations by Small-Molecule Modulators on Voltage-Dependent Hysteresis of Transmembrane Ionic Currents

[3] Francesca Ferraresso, et al. Mol Pharm. Comparison of DLin-MC3-DMA and ALC-0315 for siRNA Delivery to Hepatocytes and Hepatic Stellate Cells

[4] Han Han Ly, et al. Mol Pharm. Optimization of Lipid Nanoparticles for saRNA Expression and Cellular Activation Using a Design-of-Experiment Approach

[5] Hsin-Yen Cho, et al. Biomedicines. Effective Perturbations on the Amplitude and Hysteresis of Erg-Mediated Potassium Current Caused by 1-Octylnonyl 8-[(2-hydroxyethyl)[6-oxo-6(undecyloxy)hexyl]amino]-octanoate (SM-102), a Cationic Lipid

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Keywords: SM-102, SM102 supplier, Liposome, inhibitors, activators

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