All AbMole products are for research use only, cannot be used for human consumption.
ATX-100 is a novel cationic lipid (pKa = 6.38). It has been used in the generation of lipid nanoparticles (LNPs) for the delivery of siRNA. Intravenous administration of LNPs containing ATX-100 and encapsulating Factor VII siRNA decrease Factor VII blood levels in mice.
| Molecular Weight | 755.23 |
| Formula | C44H86N2O5S |
| CAS Number | 2230647-37-5 |
| Solubility (25°C) | DMSO 90 mg/mL Ethanol 60 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Related Liposome Products |
|---|
| Sunflower phospholipids
Sunflower phospholipids can be used for the preparation of liposomes. It has been shown to play important roles in many important areas, including maintenance of cellular structure, fat metabolism, memory, nerve signaling, acting as a precursor of important neurotransmitters, and liver health. |
| DSPE-PEG2000-COOH
DSPE-PEG2000-COOH is a carboxyl-terminated PEG derivative of phosphatidylserine with a molecular weight of approximately 2000. DSPE provides lipophilicity and membrane-fusion properties, whilst PEG enhances stability; the carboxyl group can be used for coupling reactions with amine groups. DSPE-PEG2000-COOH is commonly used in the preparation of liposomes and nanolipid carriers, and can form micelles for drug delivery and biomedical research. |
| β-Sitosterol
Replacing cholesterol in lipid nanoparticle (LNP) formulations with β-Sitosterol, a natural phytosterol, significantly improves mRNA delivery. |
| DLPC
DLPC is a lRH-1 agonist; regulates bile acid metabolism. |
| DLin-MC3-DMA
DLin-MC3-DMA is the most potent cationic lipid that has been synthesized for lipid nanoparticles (LNPs) to deliver the siRNA. |
All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.
Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2026 AbMole BioScience. All Rights Reserved.
