Dimethyldioctadecylammonium bromide is a synthetic cationic lipid consisting of a positively charged ammonium head group and two long hydrophobic tails that can be used to form liposomes and other lipid-based nanoparticles, which are commonly used in studies related to gene delivery and vaccine development.
| Molecular Weight | 630.95 |
| Formula | C38H80BrN |
| CAS Number | 3700-67-2 |
| Form | Solid |
| Solubility (25°C) | DMSO 4 mg/mL |
| Storage | 4°C, dry, sealed |
| Species | Mouse | Rat | Rabbit | Guinea pig | Hamster | Dog |
| Weight (kg) | 0.02 | 0.15 | 1.8 | 0.4 | 0.08 | 10 |
| Body Surface Area (m2) | 0.007 | 0.025 | 0.15 | 0.05 | 0.02 | 0.5 |
| Km factor | 3 | 6 | 12 | 8 | 5 | 20 |
| Animal A (mg/kg) = Animal B (mg/kg) multiplied by | Animal B Km |
| Animal A Km |
For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.
| Related Liposome Products |
|---|
| Vaxfectin
Vaxfectin is a cationic lipid adjuvant for use in the study of plasmid DNA and protein-based vaccines. |
| 98N12-5
98N12-5 is a novel ionizable lipid that can be used in studies related to siRNA delivery. |
| YSK 05
YSK 05 is a pH-sensitive cationic lipid with good gene silencing and hemolytic activity, overcomes inhibition of endosomal escape by polyethylene glycolization, and improves intracellular transport of non-viral vectors.YSK 05 is effective in enhancing siRNA delivery both in vitro and in vivo.YSK 05 is a pH-sensitive cationic lipid with good gene silencing and hemolytic activity. |
| 1,5-Dihexadecyl N-(3-carboxy-1-oxopropyl)-L-glutamate
1,5-Dihexadecyl N-(3-carboxy-1-oxopropyl)-L-glutamate is a lipid that can be used in the synthesis of phospholipid vesicles to improve protein encapsulation. |
| AA-T3A-C12
AA-T3A-C12 is an anisamide ligand-bolus lipidoid (AA-lipidoid) that can be used to mediate bulk RNA delivery and transfection of activated fibroblasts. |
Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2023 AbMole BioScience. All Rights Reserved.
