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PEG2000-DSPE can be used to synthesize stable nucleic acid lipid particles (SNALPs).SNALPs represent some of the earliest and best-functioning siRNA-ABC nanoparticles described.
| Molecular Weight | 2808.74 |
| Formula | C45H87NNaO11P |
| CAS Number | 247925-28-6 |
| Form | Solid |
| Solubility (25°C) | DMSO 10 mg/mL |
| Storage | 4°C, protect from light, dry, sealed |
| Related Liposome Products |
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| Sunflower phospholipids
Sunflower phospholipids can be used for the preparation of liposomes. It has been shown to play important roles in many important areas, including maintenance of cellular structure, fat metabolism, memory, nerve signaling, acting as a precursor of important neurotransmitters, and liver health. |
| DSPE-PEG2000-COOH
DSPE-PEG2000-COOH is a carboxyl-terminated PEG derivative of phosphatidylserine with a molecular weight of approximately 2000. DSPE provides lipophilicity and membrane-fusion properties, whilst PEG enhances stability; the carboxyl group can be used for coupling reactions with amine groups. DSPE-PEG2000-COOH is commonly used in the preparation of liposomes and nanolipid carriers, and can form micelles for drug delivery and biomedical research. |
| β-Sitosterol
Replacing cholesterol in lipid nanoparticle (LNP) formulations with β-Sitosterol, a natural phytosterol, significantly improves mRNA delivery. |
| DLPC
DLPC is a lRH-1 agonist; regulates bile acid metabolism. |
| DLin-MC3-DMA
DLin-MC3-DMA is the most potent cationic lipid that has been synthesized for lipid nanoparticles (LNPs) to deliver the siRNA. |
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