Free shipping on all orders over $ 500

JNK Jun N-terminal kinase

Inhibitors

Cat.No.  Name Information
M2076 SP600125 SP600125 is a novel and selective inhibitor of c-Jun N-terminal kinase (JNK), inhibited phosphorylation of c-Jun with an IC50 of 5-10 microM.
M11008 IQ-3 IQ-3 is a specific inhibitor of the c-JNK family and is more selective for JNK3. IQ-3 for JNK1, JNK2, and JNK3 Kd The values are 0.24 μM, 0.29 μM, and 0.066 μM, respectively.
M10695 WHI-P258 WHI-P258 is an inhibitor of JAK3 with a Ki value of 72 μM.
M10664 Isovitexin Isovitexin is a flavonoid isolated from rice hulls of Oryza sativa, possesses anti-inflammatory and anti-oxidant activities. Isovitexin inhibits the activation of NF-κB.
M10633 AS601245 AS601245 is an orally active, selective, ATP competitive JNK (c-Jun NH2-terminal protein kinase) inhibitor with IC50 values of 150, 220, and 70 nM for JNK human isoforms (hJNK1, hJNK2, and hJNK3), respectively.
M10365 L-JNKI-1 L-JNKI-1 is a cell-permeable peptide inhibitor specific for JNK.
M9718 DB07268 DB07268 is is a potent and selective JNK1 inhibitor, with IC50 of 9 nM.
M9388 Tanzisertib Tanzisertib (CC-930) is a potent JNK1/2/3 inhibitor with IC50s of 61/7/6 nM, respectively.
M9176 DTP3 DTP3 is a selective GADD45β/MKK7 inhibitor, which inhibits cancer-selective NF-κB survival pathway.
M9175 Vacquinol-1 Vacquinol-1 is an MKK4 activator, which rapidly and selectively induces glioma cell death.
M8946 IQ-1S IQ-1S is a potent and selective JNK inhibitor with Kds of 100 nM, 240 nM, and 360 nM for JNK3, JNK1, and JNK2, respectively.
M8921 Bentamapimod Bentamapimod, also known as AS602801, is an ATP-competitive JNK inhibitor with IC50 of 80 nM, 90 nM, and 230 nM for JNK1, JNK2, and JNK3, respectively.
M5145 Anisomycin Anisomycin is a pyrrolidine antibiotic, which inhibits protein synthesis, and also act as a JNK activator.
M4746 Isovitexin Isovitexin, a flavonoid obtained from Asian rice seeds, has antioxidant and anti-inflammatory activities. Isovitexin acts like an inhibitor of JNK1/2 and inhibits NF-κB activation.
M4361 Polyphyllin-I Polyphyllin I is a bioactive ingredient extracted from Paris Polyphylla with strong anti-tumor activity. Polyphyllin I is an activator of the JNK signaling pathway and an inhibitor of PDK1/Akt/mTOR signaling. Polyphyllin I induces autophagy, G2/M phase arrest and apoptosis.
M4340 Cinobufagin Cinobufagin is a cardiotoxic bufanolide steroid secreted by the Asiatic toad Bufo gargarizans.
M3713 YS-49 YS 49 has potential as a therapeutic strategy for the pathogenesis of Ang II-related vascular diseases such as hypertension and atherosclerosis, via the induction of HO-1 gene activity.
M2785 JNK Inhibitor IX (SC202671) JNK inhibitor IX is a selective and potent JNK inhibitor with pIC50 of 6.5 and 6.7 for JNK2 and JNK3, respectively.
M2076 SP600125 SP600125 is a novel and selective inhibitor of c-Jun N-terminal kinase (JNK), inhibited phosphorylation of c-Jun with an IC50 of 5-10 microM.
M2013 JNK-IN-8 JNK-IN-8 is a selective JNK inhibitor that inhibits phosphorylation of c-Jun.



Contact Us

Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2020 AbMole BioScience. All Rights Reserved.