| Cat.No. | Name | Information |
|---|---|---|
| M8970 | MLN120B | MLN120B is a potent and effective, ATP competitive IKKβ inhibitor with IC50 value of 20 μM. |
| M2769 | IMD 0354 | IMD-0354 is an IKKβ inhibitor and blocks IκBα phosphorylation in NF-κB pathway. |
| M2432 | Bardoxolone Methyl | Bardoxolone Methyl is an IKK inhibitor with potent pro-apoptotic and anti-inflammatory activities, as well as an activator of the Nrf2 pathway and an inhibitor of the NF-κB pathway. |
| M2300 | TPCA-1 | TPCA-1 is an inhibitor of IKK-2 with IC50 of 17.9 nM. |
| M2060 | SC-514 | SC-514 is a selective and reversible inhibitor of IκB kinase 2 (IKK2) with IC50 of 3-12 μM. |
| M2040 | BAY 11-7082 | BAY 11-7082 is an inhibitor of cytokine-induced IκB-α phosphorylation (IC50 ~ 10 μM). BAY 11-7082 inhibits ubiquitin-specific protease USP7 and USP21 (IC50=0.19, 0.96 μM, respectively). |
| M21651 | BAY-985 | BAY-985 is a highly potent, orally active and selective ATP-competitive dual inhibitor of TBK1 and IKKε with IC50s of 2/30 and 2 nM for TBK1 (low/high ATP) and IKKε, respectively. |
| M21043 | Malachite green | Malachite green is a synthetic dyestuff and antimicrobial with potential carcinogenicity. |
| M14590 | MRT67307 | MRT67307 is a dual inhibitor of the IKKε and TBK-1 with IC50s of 160 and 19 nM, respectively. MRT67307 also inhibits ULK1 and ULK2 with IC50s of 45 and 38 nM, respectively. MRT67307 also blocks autophagy in cells. |
| M14588 | IKK 16 hydrochloride | IKK 16 hydrochloride is a selective IκB kinase (IKK) inhibitor for IKK2, IKK complex and IKK1 with IC50s of 40 nM, 70 nM and 200 nM, respectively. |
| M14586 | GSK8612 | GSK8612 is a highly selective and potent Tank-binding Kinase-1 (TBK1) inhibitor, with a pIC50 of 6.8 for recombinant TBK1. |
| M14585 | Bay 65-1942 hydrochloride | Bay 65-1942 hydrochloride is an ATP-competitive and selective IKKβ inhibitor. |
| M11553 | WS3 | WS3 is a β cell proliferation inducer, which can promote the β cell proliferation of primary rat and human islets. WS3 can be used in the study of type I diabetes. |
| M11455 | ACHP Hydrochloride | ACHP Hydrochloride (IKK-2 Inhibitor VIII) is a potent, selective IKK-β Inhibitor with an IC50 of 8.5 nM. |
| M9546 | TBK1/IKKε-IN-5 | TBK1/IKKε-IN-5 (compound 1) is a dual TBK1 and IKKε inhibitor, with IC50 values of 1 nM and 5.6 nM for TBK1 and IKKε, respectively. |
| M8961 | LY2409881 trihydrochloride | LY2409881 trihydrochloride is a potent and selective IKK2 inhibitor with IC50 of 30 nM. |
| M8952 | WS6 | WS6 is a novel beta cell proliferation simulator, which promotes β cell proliferation in rodent and human primary islets with EC50 of 0.28 uM(R7T1 cell viability). |
| M6766 | GS 143 | GS 143 is a β-TrCP1 ligase inhibitor. |
| M6502 | BI 605906 | BI 605906 is a selective IKKβ inhibitor. |
| M6180 | AZD3264 | AZD3264 is a novel IKK2 inhibitor. |
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