IκB/IKK Inhibitor of NF-κB/inhibitor of nuclear factor kappa-B kinase

Cat.No.	Name	Information
M2040	BAY 11-7082	BAY 11-7082 is an inhibitor of cytokine-induced IκB-α phosphorylation (IC50 ~ 10 μM). BAY 11-7082 inhibits ubiquitin-specific protease USP7 and USP21 (IC50=0.19, 0.96 μM, respectively).
M2300	TPCA-1	TPCA-1 is an inhibitor of IKK-2 with IC50 of 17.9 nM.
M2769	IMD 0354	IMD-0354 is an IKKβ inhibitor and blocks IκBα phosphorylation in NF-κB pathway.
M2060	SC-514	SC-514 is a selective and reversible inhibitor of IκB kinase 2 (IKK2) with IC50 of 3-12 μM.
M2432	Bardoxolone Methyl	Bardoxolone Methyl is an IKK inhibitor with potent pro-apoptotic and anti-inflammatory activities, as well as an activator of the Nrf2 pathway and an inhibitor of the NF-κB pathway.
M27830	BOT-64	BOT-64 is an inhibitory κB (IκB) kinase β (IKKβ) inhibitor with an IC50 of 1 µM. BOT-64 blocks lipopolysaccharide-induced nuclear factor-κB activation and nuclear factor-κB-regulated inflammatory gene transcription.
M20338	WAY-388756	WAY-388756 is a IKKb inhibitor.
M20027	WAY-113178	WAY-113178 is a IkB kinase-beta (IKKb) inhibitor.
M14589	IKK-IN-1	IKK-IN-1 is an inhibitor of IKK.
M14587	TBK1/IKKε-IN-2	TBK1/IKKε-IN-2 is a dual TBK1 and IKKε inhibitor.
M11455	ACHP Hydrochloride	ACHP Hydrochloride (IKK-2 Inhibitor VIII) is a potent, selective IKK-β Inhibitor with an IC50 of 8.5 nM.
M6772	GSK 319347A	GSK319347A is a dual inhibitor of TBK1 and IKKε with IC50s of 93 nM and 469 nM, respectively.