| Cat.No. | Name | Information |
|---|---|---|
| M2040 | BAY 11-7082 | BAY 11-7082 is an inhibitor of cytokine-induced IκB-α phosphorylation (IC50 ~ 10 μM). BAY 11-7082 inhibits ubiquitin-specific protease USP7 and USP21 (IC50=0.19, 0.96 μM, respectively). |
| M2300 | TPCA-1 | TPCA-1 is an inhibitor of IKK-2 with IC50 of 17.9 nM. |
| M2769 | IMD 0354 | IMD-0354 is an IKKβ inhibitor and blocks IκBα phosphorylation in NF-κB pathway. |
| M2060 | SC-514 | SC-514 is a selective and reversible inhibitor of IκB kinase 2 (IKK2) with IC50 of 3-12 μM. |
| M2432 | Bardoxolone Methyl | Bardoxolone Methyl is an IKK inhibitor with potent pro-apoptotic and anti-inflammatory activities, as well as an activator of the Nrf2 pathway and an inhibitor of the NF-κB pathway. |
| M8970 | MLN120B | MLN120B is a potent and effective, ATP competitive IKKβ inhibitor with IC50 value of 20 μM. |
| M30095 | IMD-0560 | IMD-0560 is a novel IκB kinase β inhibitor. |
| M28613 | BAY32-5915 | BAY32-5915 is a potent IKKα inhibitor with an IC50 value of 60 nM. BAY32-5915 has not affect Doxorubicin-induced NF-κB activation. |
| M27830 | BOT-64 | BOT-64 is an inhibitory κB (IκB) kinase β (IKKβ) inhibitor with an IC50 of 1 µM. BOT-64 blocks lipopolysaccharide-induced nuclear factor-κB activation and nuclear factor-κB-regulated inflammatory gene transcription. |
| M20338 | WAY-388756 | WAY-388756 is a IKKb inhibitor. |
| M20027 | WAY-113178 | WAY-113178 is a IkB kinase-beta (IKKb) inhibitor. |
| M14589 | IKK-IN-1 | IKK-IN-1 is an inhibitor of IKK. |
| M14587 | TBK1/IKKε-IN-2 | TBK1/IKKε-IN-2 is a dual TBK1 and IKKε inhibitor. |
| M6772 | GSK 319347A | GSK319347A is a dual inhibitor of TBK1 and IKKε with IC50s of 93 nM and 469 nM, respectively. |
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