Catalog

Histamine Receptor Histamine Receptor

Inhibitors

Cat.No.	Name	Information
M9459	Mequitazine	Mequitazine is a potent, nonsedative and long-acting histamine H1 antagonist.
M9290	S 38093	S 38093 is an inverse agonist at histamine H3 receptors, displays a moderate affinity for rat, mouse and human H3 receptors with Ki of 8.8, 1.44 and 1.2µM, respectively.
M9172	Emedastine Difumarate	Emedastine Difumarate is a second generation, selective histamine H1 receptor antagonist with anti-allergic activity.
M6111	Meta-Fexofenadine	Fexofenadine is a nonsedating antihistamine drug which is indicated for treatment of seasonal allergic rhinitis.
M5942	Roxatidine Acetate HCl	Roxatidine Acetate HCl is a specific and competitive histamin H2-receptor antagonist, with IC50 of 3.2 μM, inhibits gastric acid secretion and ulcer formation.
M5921	Ranitidine HCl	Ranitidine is a histamine H2-receptor antagonist, used to treat stomach or intestinal ulcers.
M5792	Mizolastine	Mizolastine is a histamine H1-receptor antagonist with IC50 of 47 nM used in the treatment of hay fever (seasonal allergic rhinitis), hives and other allergic reactions.
M5752	Loratadine	Loratadine is a histamine H1 receptor antagonist, used to treat allergies. Also acts as a selective inhibitor of B(0)AT2 with IC50 of 4 μM.
M5741	Lidocaine	Lidocaine is a selective inverse peripheral histamine H1-receptor agonist with an IC50 of >32 μM.
M5727	Lafutidine	Lafutidine, a newly developed histamine H(2)-receptor antagonist, inhibits gastric acid secretion.
M5722	Ketotifen Fumarate	Ketotifen Fumarate is a fumaric acid salt of ketotifen which is a H1-antihistamine and mast cell stabilizer.
M5692	Histamine	Histamine is an organic nitrogenous compound involved in local immune responses as well as regulating physiological function in the gut and acting as a neurotransmitter.
M5638	Famotidine	Famotidine is a histamine H2–receptor antagonist with IC50 of 0.6 mM, commonly used to treat heartburn, GERD, ulcers, and other digestive conditions.
M5615	Epinastine	Epinastine(WAL801) is an antihistamine and mast cell stabilizer that is used in eye drops to treat allergic conjunctivitis.
M5578	Dimenhydrinate	Dimenhydrinate is an anti-emetic and anti-histamine commonly available over-the-counter as a motion sickness remedy.
M5555	Decloxizine dihydrochloride	Decloxizine dihydrochloride(UCB-1402; NSC289116) is a histamine 1 receptor antagonist.
M5514	Chlorphenoxamine	Chlorphenoxamine is an antihistamine and anticholinergic used as an antipruritic and antiparkinsonian agent.
M5506	Cetirizine Dihydrochloride	Cetirizine 2Hcl, a second-generation antihistamine, is a major metabolite of hydroxyzine, and a racemic selective H1 receptor inverse agonist used in the treatment of allergies, hay fever, angioedema, and urticaria.
M5458	Bilastine	Bilastine is a selective histamine H1 receptor antagonist used for treatment of allergic rhinoconjunctivitis and urticaria.
M5393	Alcaftadine	Alcaftadine is a high affinity ligand for the H1 receptor, with a pKi (8.5) that is comparable with that of other H1 antihistamines. Alcaftadine is also an antagonist for H2 and H4 receptors with no affinity for the H3 receptor.
M3754	Nedocromil	Nedocromil is a pyranoquinolone derivative that inhibits activation of inflammatory cells which are associated with asthma, including eosinophils, neutrophils, macrophages, mast cells, monocytes, and platelets.
M3665	Promethazine hydrochloride	Promethazine hydrochloride is a potent histamine H1 receptor antagonist, used as a sedative and antiallergic medication.
M3487	Azelastine hydrochloride	Azelastine hydrochloride is a potent, second-generation, selective, histamine antagonist.
M3458	Chlorpheniramine Maleate	Chlorpheniramine (Chlorpheniramine maleate, Chlorphenamine) is an histamine H1 receptor antagonist with IC50 of 12 nM.
M3454	Olopatadine hydrochloride	Olopatadine hydrochloride is a histamine blocker and mast cell stabilizer with an IC50 of 559 μM for the release of histamine.
M3431	Nizatidine	Nizatidine is a histamine H2 receptor antagonist with IC50 of 0.9 nM, also inhibits AChE with IC50 of 6.7 μM.
M3385	Cimetidine	Cimetidine, a histamine congener, competitively inhibits histamine binding to histamine H2 receptors.
M3318	Clemastine Fumarate	Clemastine Fumarate (Clemastine) is a selective histamine H1 receptor antagonist with IC50 of 3 nM.
M3226	Brompheniramine hydrogen maleate	Brompheniramine hydrogen maleate is a histamine H1 receptors antagonist.
M3091	Tripelennamine hydrochloride	Tripelennamine is a widely used H1 antagonist, inhibiting PhIP glucuronidation with IC50 of 30 μM.
M2990	Rupatadine Fumarate	Rupatadine is an inhibitor of PAFR and histamine (H1) receptor with K_i of 550 nM and 102 nM, respectively.
M2935	Pheniramine Maleate	Pheniramine Maleate is an antihistamine with anticholinergic properties used to treat allergic conditions such as hay fever or urticaria.
M2919	Pemirolast potassium	Pemirolast potassium (BMY 26517) is a histamine H1 antagonist and mast cell stabilizer that acts as an antiallergic agent.
M2811	Levodropropizine	Levodropropizine possess anti-allergic and inhibits histamine receptor, reduces cough by interfering with stimulus activation of peripheral endings of sensory nerves and by modulation of neuropeptides involved in the cough reflex.
M2784	JNJ-7777120	JNJ-7777120 is the first potent and selective non-imidazole histamine H4 receptor antagonist with K_i of 4.5 nM, exhibits >1000-fold selectivity over the other histamin receptors.
M2760	Hydroxyzine dihydrochloride	Hydroxyzine is a histamine H1-receptor antagonist, inhibits binding of [³H]pyrilamine/[³H]desloratadine to human histamine H1 receptor with IC50 of 10 nM/19 nM.
M2756	Histamine dihydrochloride	Histamine is an organic nitrogen compound, acts on target cells in mammalian brain via stimulation of Histamine 1/2.
M2699	Fexofenadine hydrochloride	Fexofenadine inhibits histamine H1 receptor with IC50 of 246 nM.
M2660	Ebastine	Ebastinea is a potent H1-histamine receptor antagonist, used for allergic disorders.
M2650	Doxepin hydrochloride	Doxepin is a psychotropic agent with tricyclic antidepressant and anxiolytic properties.
M2621	Desloratadine	Desloratadine is a potent antagonist for human histamine H1 receptor with IC50 of 51 nM.
M2582	Clemizole	Clemizole is a H1 histamine receptor antagonist with IC50 Value of 8 mM (NS4B).
M2545	Cyclizine dihydrochloride	Cyclizine 2HCl is a piperazine derivative with Histamine H1 receptor antagonist activity.
M2522	Ciproxifan	Ciproxifan is a highly potent and selective histamin H3-receptor antagonist with IC50 of 9.2 nM, with low apparent affinity at other receptor subtypes.
M2477	Buclizine hydrochloride	Buclizine hydrochloride is an antihistamine and anticholinergic of the piperazine derivative family.
M2452	Betahistine dihydrochloride	Betahistine is a histamine H3 receptors inhibitor with IC50 of 1.9 μM.
M2449	Bepotastine Besilate	Bepotastine is a non-sedating, selective antagonist of histamine 1 (H1) receptor with pIC50 of 5.7.
M2416	Azatadine dimaleate	Azatadine is an histamine and cholinergic inhibitor with IC50 of 6.5 nM and 10 nM, respectively.
M2398	Antazoline hydrochloride	Antazoline hydrochloride is a first generation antihistamine, binding to the histamine H1 receptor and blocking the action of endogenous histamine.
M2088	Ciproxifan maleate	Ciproxifan is an orally bioavailable, extremely potent histamine H3 inverse agonist/antagonist.

Signaling Pathways

Product Type

Histamine Receptor Histamine Receptor

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