| Cat.No. | Name | Information |
|---|---|---|
| M1738 | Niltubacin | Niltubacin, as an inactive derivative of Tubacin, is a highly potent and selective, reversible cell-permeable inhibitor of HDAC6. |
| M1742 | Tubacin | Tubacin (Tubulin Acetylation Inducer) is a highly potent and selective, reversible cell-permeable inhibitor of HDAC6 with IC50 of 0.004µM. |
| M1780 | Vorinostat | Vorinostat (SAHA, Zolinza, MK-0683) is a selective and potent histone deacetylase (HDAC) inhibitor with the IC50 value of 10 nM for HDAC-1. |
| M2007 | Romidepsin (FK228) | Romidepsin (FK228, Depsipeptide, FR 901228, NSC 630176) is a structurally unique, potent HDAC1 and HDAC2 inhibitor with IC50 of 36 nM and 47 nM, respectively.*The compound is unstable in solutions, freshly prepared is recommended |
| M3988 | Sulforaphane | Sulforaphane (SFN) extracted from broccoli sprout is an agent with potent anti-oxidant and anti-inflammatory activity. |
| M1791 | Entinostat (MS-275) | Entinostat (MS-275) is an oral and selective class I HDAC inhibitor, with IC50s of 243 nM, 453 nM, and 248 nM for HDAC1, HDAC2, and HDAC3, respectively. |
| M1748 | LBH589 (Panobinostat) | LBH589 (Panobinostat) is a novel broad-spectrum HDAC inhibitor for MOLT-4 and Reh cells with IC50 of 5 and 20 nM, respectively. |
| M4986 | LMK-235 | LMK235 is a HDAC inhibitor, previously shown to be a novel and specific inhibitor of human HDAC4 and 5, with IC50 values of 0.49 μM (A2780) and 0.32 μM (A2780 CisR). |
| M9638 | 4-Phenylbutyric acid (4-PBA) | 4-Phenylbutyric acid is an inhibitor of HDAC, inhibits the growth of NSCLC Cell Lines at 2 mM. |
| M6176 | TMP195 | TMP195 is a selective, first-in-class, class IIa HDAC inhibitor with IC50 of 300 nM in cell-based class IIa HDAC assays. |
| M2123 | Rocilinostat | Rocilinostat (ACY-1215) is an HDAC6-selective inhibitor with IC50 of 5 nM. |
| M2119 | JNJ-26481585 | JNJ-26481585 (Quisinostat) is a novel second-generation class I HDAC inhibitor. |
| M2111 | CUDC-907 | CUDC-907 is a potent, orally-available small molecule dual PI3K and HDAC inhibitor. |
| M2014 | MC1568 | MC1568 is a selective class II (IIa) histone deacetylas (HDAC II) inhibitor with IC50 of 220 nM. |
| M1993 | Droxinostat | Droxinostat is a selective inhibitor of HDAC3, HDAC6 and HDAC8 with IC50 of 16.9 μM, 2.47μM and 1.46 μM, respectively. |
| M1876 | Valproic acid sodium salt | Valproic acid (VPA) is a histone deacetylase inhibitor which is reported to enhance central GABAergic neurotransmission and inhibit Na+ channels. |
| M1813 | PCI-24781 | PCI-24781 is a novel and potent histone deacetylase (HDAC) inhibitor with IC50 value of 0.43 to 2.7 μM. *The compound is unstable in solutions, freshly prepared is recommended |
| M1790 | MGCD0103 | MGCD0103 is a novel HDAC inhibitor, highly specific for classes I and IV HDACs, with IC50 of 0.15, 0.29 and 1.66 μM for HDAC 1, HDAC 2 and HDAC 3 respectively. |
| M1778 | SB939 | SB939 is a novel potent and orally active histone deacetylase with high tumor exposure and efficacy in mouse models of colorectal cancer. |
| M1775 | Tubastatin A hydrochloride | Tubastatin A is a potent and selective HDAC6 inhibitor with IC50 values of 15 nM. |
| M1747 | LAQ824 | LAQ824 (NVP-LAQ824) is a potent novel histone deacetylase (HDAC) inhibitor with an IC50 of 0.032 μM. |
| M1730 | Givinostat hydrochloride monohydrate | ITF2357 (Givinostat, Gavinostat) is a histone deacetylase inhibitor. The IC50 values for maize HDAC preparations HD2, HD-1B and HD-1A are 10, 7.5 and 16 nM respectively. |
| M1693 | CUDC-101 | CUDC-101 is a potent multitargeted HDAC, EGFR and HER2 inhibitor with IC50 of 4.4, 2.4, and 15.7 nM, respectively. |
| M1670 | Belinostat | Belinostat (PXD101) is a novel HDAC inhibitor with an IC50 of 27 nM. |
| M1458 | SIS17 | SIS17 is a histone deacetylase 11 (HDAC 11) inhibitor with an IC50 value of 0.83 μM. |
| M54212 | Ac-Arg-Gly-Lys(Ac)-AMC | Ac-Arg-Gly-Lys(Ac)-AMC is a substrate for HDAC. |
| M53352 | Chlamydocin | Chlamydocin, a fungal metabolite, is a highly potent HDAC inhibitor, with an IC50 of 1.3 nM. |
| M53351 | HDAC-IN-30 | HDAC-IN-30 is a novel multi-target HDAC inhibitor, including HDAC1 (IC50=13.4 nM),HDAC2 (IC50=28.0 nM), HDAC3 (IC50=9.18 nM), HDAC6 (IC50=42.7 nM), HDAC8 (IC50=131 nM). |
| M43414 | JPS014 TFA | JPS014 TFA is a benzamide-based Von Hippel-Lindau (VHL) E3-ligase proteolysis targeting chimeras (PROTAC). |
| M41507 | HDAC-IN-64 | HDAC-IN-64 is a HDAC inhibitor. |
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