Cat.No. | Name | Information |
---|---|---|
M1738 | Niltubacin | Niltubacin, as an inactive derivative of Tubacin, is a highly potent and selective, reversible cell-permeable inhibitor of HDAC6. |
M1742 | Tubacin | Tubacin (Tubulin Acetylation Inducer) is a highly potent and selective, reversible cell-permeable inhibitor of HDAC6 with IC50 of 0.004µM. |
M1780 | Vorinostat | Vorinostat (SAHA, Zolinza, MK-0683) is a selective and potent histone deacetylase (HDAC) inhibitor with the IC50 value of 10 nM for HDAC-1. |
M2007 | Romidepsin (FK228) | Romidepsin (FK228, Depsipeptide, FR 901228, NSC 630176) is a structurally unique, potent HDAC1 and HDAC2 inhibitor with IC50 of 36 nM and 47 nM, respectively.*The compound is unstable in solutions, freshly prepared is recommended |
M3988 | Sulforaphane | Sulforaphane (SFN) extracted from broccoli sprout is an agent with potent anti-oxidant and anti-inflammatory activity. |
M1791 | Entinostat (MS-275) | Entinostat (MS-275) is an oral and selective class I HDAC inhibitor, with IC50s of 243 nM, 453 nM, and 248 nM for HDAC1, HDAC2, and HDAC3, respectively. |
M1748 | LBH589 (Panobinostat) | LBH589 (Panobinostat) is a novel broad-spectrum HDAC inhibitor for MOLT-4 and Reh cells with IC50 of 5 and 20 nM, respectively. |
M4986 | LMK-235 | LMK235 is a HDAC inhibitor, previously shown to be a novel and specific inhibitor of human HDAC4 and 5, with IC50 values of 0.49 μM (A2780) and 0.32 μM (A2780 CisR). |
M9638 | 4-Phenylbutyric acid (4-PBA) | 4-Phenylbutyric acid is an inhibitor of HDAC, inhibits the growth of NSCLC Cell Lines at 2 mM. |
M6176 | TMP195 | TMP195 is a selective, first-in-class, class IIa HDAC inhibitor with IC50 of 300 nM in cell-based class IIa HDAC assays. |
M7374 | TC-H 106 | TC-H 106 is a class I histone deacetylase inhibitor, with IC50 values of 150 nM , 760 nM and 370 nM for HDAC 1, 2, and 3, respectively. |
M7055 | NSC 3852 | NSC 3852 is a histone deacetylase inhibitor. |
M6178 | Tucidinostat (Chidamide) | Tucidinostat (Chidamide) is a low nanomolar inhibitor of HDAC1, 2, 3, and 10, the HDAC isotypes well documented to be associated with the malignant phenotype with IC50 values of 95, 160, 67, 78 nM for HDAC1, 2, 3, 10 respectively. |
M6073 | WT161 | WT-161 is a potent and selective HDAC6 inhibitor with an IC50 of 0.40 nM. |
M6070 | EDO-S101 | EDO-S101 is a pan HDAC inhibitor; inhibits HDAC1, HDAC2 and HDAC3 with IC50 values of 9, 9 and 25 nM, respectively. |
M5259 | Citarinostat | Citarinostat (ACY-241) is an orally available selective HDAC6 inhibitor with IC50 of 2.6 nM and 46 nM for HDAC6 and HDAC3, respectively. It has 13 to 18-fold selectivity towards HDAC6 in comparison to HDAC1-3. |
M5200 | BRD73954 | BRD73954 ia a potent and selective HDAC inhibitor with IC50 of 36 nM and 120 nM for HDAC6 and HDAC8, respectively. |
M4609 | Raddeanin-A | Raddeanin-A displays moderate inhibitory activity against histone deacetylases (HDACs) and has high antiangiogenic potency, antitumor activity. |
M3979 | Caffeic acid | Caffeic acid is an endogenous phenolic phytochemical compound that exists in plants and many foods. |
M3888 | CAY10603 (BML-281) | CAY10603 (BML-281) is a potent and selective inhibitor of HDAC6 with IC50 of 2 pM. |
M3643 | TMP269 | TMP269 is a potent, selective class IIa HDAC inhibitor with IC50 of 157 nM, 97 nM, 43 nM and 23 nM for HDAC4, HDAC5, HDAC7 and HDAC9, respectively.In addition, TMP269 significantly promotes reprogramming. |
M3427 | Divalproex Sodium | Divalproex Sodium consists of a compound of sodium valproate and valproic acid in a 1:1 molar relationship in an enteric coated form. |
M3405 | AR-42 | AR-42 is an HDAC inhibitor with IC50 of 30 nM. |
M3395 | M344 | M344 is a potent HDAC inhibitor with IC50 of 100 nM and able to induce cell differentiation. |
M3243 | Pyroxamide | Pyroxamide (NSC 696085) is a potent, affinity-purified HDAC1 inhibitor with ID50 of 100 nM. |
M3022 | Sodium Phenylbutyrate | Sodium Phenylbutyrate (4-PBA sodium) is a transcriptional regulators that act by altering chromatin structure via the modulation of HDAC activity. |
M3002 | Scriptaid | Scriptaid is an inhibitor of HDAC. It shows a greater effect on acetylated H4 than H3. |
M2975 | RG2833 | RG2833 (RGFP109) is a brain-penetrant HDAC inhibitor with IC50 of 60 nM and 50 nM for HDAC1 and HDAC3, respectively. |
M2878 | Nexturastat A | Nexturastat A is a potent and selective HDAC6 inhibitor with IC50 of 5 nM, >190-fold selectivity over other HDACs. |
M2400 | Apicidin | Apicidin is a potent nonselective HDAC inhibitor with IC50 of 0.7 nM. |
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