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HDAC Histone deacetylases

Cat.No.  Name Information
M1738 Niltubacin Niltubacin, as an inactive derivative of Tubacin, is a highly potent and selective, reversible cell-permeable inhibitor of HDAC6.
M1742 Tubacin Tubacin (Tubulin Acetylation Inducer) is a highly potent and selective, reversible cell-permeable inhibitor of HDAC6 with IC50 of 0.004µM.
M1780 Vorinostat Vorinostat (SAHA, Zolinza, MK-0683) is a selective and potent histone deacetylase (HDAC) inhibitor with the IC50 value of 10 nM for HDAC-1.
M2007 Romidepsin (FK228) Romidepsin (FK228, Depsipeptide, FR 901228, NSC 630176) is a structurally unique, potent HDAC1 and HDAC2 inhibitor with IC50 of 36 nM and 47 nM, respectively.*The compound is unstable in solutions, freshly prepared is recommended
M3988 Sulforaphane Sulforaphane (SFN) extracted from broccoli sprout is an agent with potent anti-oxidant and anti-inflammatory activity.
M1791 Entinostat (MS-275) Entinostat (MS-275) is an oral and selective class I HDAC inhibitor, with IC50s of 243 nM, 453 nM, and 248 nM for HDAC1, HDAC2, and HDAC3, respectively.
M1748 LBH589 (Panobinostat) LBH589 (Panobinostat) is a novel broad-spectrum HDAC inhibitor for MOLT-4 and Reh cells with IC50 of 5 and 20 nM, respectively.
M4986 LMK-235 LMK235 is a HDAC inhibitor, previously shown to be a novel and specific inhibitor of human HDAC4 and 5, with IC50 values of 0.49 μM (A2780) and 0.32 μM (A2780 CisR).
M9638 4-Phenylbutyric acid (4-PBA) 4-Phenylbutyric acid is an inhibitor of HDAC, inhibits the growth of NSCLC Cell Lines at 2 mM.
M6176 TMP195 TMP195 is a selective, first-in-class, class IIa HDAC inhibitor with IC50 of 300 nM in cell-based class IIa HDAC assays.
M41506 HDAC-IN-58 HDAC-IN-58 is a HDAC inhibitor.
M41505 J27644 J27644 is a potent HDAC inhibitor.
M41504 SP-2-225 SP-2-225 is a selective HDAC6 inhibitor.
M41503 SGC-UBD253 SGC-UBD253 is a potent HDAC6-UBD antagonist.
M41502 HDAC8-IN-4 HDAC8-IN-4 is a selective inhibitor of HDAC8.
M41501 HDAC6-IN-19 HDAC6-IN-19 is a HDAC6 inhibitor (IC50: 2.68 nM).
M41500 KH16 KH16 is a potent and low nanomolar HDAC inhibitor.
M41499 HDAC-IN-61 HDAC-IN-61 is a potent and orally active HDAC inhibitor.
M41498 CDK/HDAC-IN-3 CDK/HDAC-IN-3 is an orally active HDACs/CDKs dual inhibitor.
M41497 HDAC-IN-60 HDAC-IN-60 is a potent histone deacetylase (HDAC) inhibitor.
M41496 HDAC-IN-59 HDAC-IN-59 is a potent histone deacetylase (HDAC) inhibitor.
M41494 TYA-018 TYA-018 is an orally active, potent and highly selective HDAC6 inhibitor.
M41493 NT160 NT160 is a highly potent class-IIa HDAC inhibitor with an IC50 value of 0.046 μM.
M41492 HDAC6-IN-16 HDAC6-IN-16 is a histone deacetylase 6 (HDAC6) inhibitor, based on Quinazolin-4(3H)-One.
M41491 Bocodepsin Bocodepsin (OKI-179) is an orally active and selective HDAC inhibitor, with antitumor activity.
M41490 PB131 PB131 is a selective and brain-permeable HDAC6 inhibitor with high binding affinity (IC50: 1.8 nM).
M41489 JPS016 TFA JPS016 is a benzamide-based Von Hippel-Lindau (VHL) E3-ligase proteolysis targeting chimeras (PROTAC).
M41488 Bocodepsin hydrochloride Bocodepsin hydrochloride (OKI-179) is an orally active and selective HDAC inhibitor, with antitumor activity.
M41487 9-Hydroxyoctadecanoic acid 9-Hydroxyoctadecanoic acid (9-HSA) is an HDAC1 inhibitor that inhibits ∼66.4% HDAC1 enzymatic activity at 5 μM.
M41486 HDAC6-IN-18 HDAC6-IN-18 is a first irreversible HDAC6 isoform selective inhibitor with potent anti-multiple myeloma activity.




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