HDAC Histone deacetylases

Cat.No.	Name	Information
M1738	Niltubacin	Niltubacin, as an inactive derivative of Tubacin, is a highly potent and selective, reversible cell-permeable inhibitor of HDAC6.
M1742	Tubacin	Tubacin (Tubulin Acetylation Inducer) is a highly potent and selective, reversible cell-permeable inhibitor of HDAC6 with IC50 of 0.004µM.
M1780	Vorinostat	Vorinostat (SAHA, Zolinza, MK-0683) is a selective and potent histone deacetylase (HDAC) inhibitor with the IC50 value of 10 nM for HDAC-1.
M2007	Romidepsin (FK228)	Romidepsin (FK228, Depsipeptide, FR 901228, NSC 630176) is a structurally unique, potent HDAC1 and HDAC2 inhibitor with IC50 of 36 nM and 47 nM, respectively.*The compound is unstable in solutions, freshly prepared is recommended
M1791	Entinostat (MS-275)	Entinostat (MS-275) is an oral and selective class I HDAC inhibitor, with IC50s of 243 nM, 453 nM, and 248 nM for HDAC1, HDAC2, and HDAC3, respectively.
M1748	LBH589 (Panobinostat)	LBH589 (Panobinostat) is a novel broad-spectrum HDAC inhibitor for MOLT-4 and Reh cells with IC50 of 5 and 20 nM, respectively.
M4986	LMK-235	LMK235 is a HDAC inhibitor, previously shown to be a novel and specific inhibitor of human HDAC4 and 5, with IC50 values of 0.49 μM (A2780) and 0.32 μM (A2780 CisR).
M9638	4-Phenylbutyric acid (4-PBA)	4-Phenylbutyric acid is an inhibitor of HDAC, inhibits the growth of NSCLC Cell Lines at 2 mM.
M6176	TMP195	TMP195 is a selective, first-in-class, class IIa HDAC inhibitor with IC50 of 300 nM in cell-based class IIa HDAC assays.
M5199	Santacruzamate A	Santacruzamate A is a picomolar level selective inhibitor of HDAC2 with an IC50 of 85.8 nM, a Class I HDAC, with relatively little inhibition of HDAC4 or HDAC6, both Class II HDACs.
M58408	CM-1758	CM-1758 is a histone deacetylase (HDAC) inhibitor. CM-1758 inhibits tumor growth in vivo. CM-1758 induces acetylation of non-histone proteins in acute myeloid leukemia cells.
M55990	T-518	T-518 is an orally active, selective, and blood-brain barrier permeable HDAC6 inhibitor with an IC50 value of 36 nM for human HDAC6.
M55989	SE-7552	SE-7552, a 2-(difluoromethyl)-1,3,4-oxadiazole (DFMO) derivative, is an orally active, highly selective, non-hydroxamate HDAC6 inhibitor with an IC50 of 33 nM.
M55988	BRD9757	BRD9757 is a potent, capless and selective HDAC6 inhibitor with an IC50 of 30 nM.
M55987	MPT0B390	MPT0B390 is an arylsulfonamide-based derivative with potent HDAC inhibitory ability.
M55986	HDAC-IN-40	HDAC-IN-40 is a potent alkoxyamide-based HDAC inhibitor with Ki values of 60 nM and 30 nM for HDAC2 and HDAC6, respectively.
M55985	(E,E)-RGFP966	(E,E)-RGFP966 is a selective and CNS permeable HDAC3 inhibitor that can be used for the research of Huntington’s disease.
M54212	Ac-Arg-Gly-Lys(Ac)-AMC	Ac-Arg-Gly-Lys(Ac)-AMC is a substrate for HDAC.
M53352	Chlamydocin	Chlamydocin, a fungal metabolite, is a highly potent HDAC inhibitor, with an IC50 of 1.3 nM.
M53351	HDAC-IN-30	HDAC-IN-30 is a novel multi-target HDAC inhibitor, including HDAC1 (IC50=13.4 nM),HDAC2 (IC50=28.0 nM), HDAC3 (IC50=9.18 nM), HDAC6 (IC50=42.7 nM), HDAC8 (IC50=131 nM).
M43414	JPS014 TFA	JPS014 TFA is a benzamide-based Von Hippel-Lindau (VHL) E3-ligase proteolysis targeting chimeras (PROTAC).
M41507	HDAC-IN-64	HDAC-IN-64 is a HDAC inhibitor.
M41506	HDAC-IN-58	HDAC-IN-58 is a HDAC inhibitor.
M41505	J27644	J27644 is a potent HDAC inhibitor.
M41504	SP-2-225	SP-2-225 is a selective HDAC6 inhibitor.
M41503	SGC-UBD253	SGC-UBD253 is a potent HDAC6-UBD antagonist.
M41502	HDAC8-IN-4	HDAC8-IN-4 is a selective inhibitor of HDAC8.
M41501	HDAC6-IN-19	HDAC6-IN-19 is a HDAC6 inhibitor (IC50: 2.68 nM).
M41500	KH16	KH16 is a potent and low nanomolar HDAC inhibitor.
M41499	HDAC-IN-61	HDAC-IN-61 is a potent and orally active HDAC inhibitor.

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HDAC Histone deacetylases

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