| Cat.No. | Name | Information |
|---|---|---|
| M22452 | 2'-C-Methyladenosine | 2'-C-Methyladenosine is an inhibitor of hepatitis C virus (HCV) replication, it inhibits HCV replicon and NS5B-catalyzed RNA synthesis with IC50 values of 0.3 μM and 1.9 μM, respectively. |
| M20732 | Pibrentasvir (ABT-530) | Pibrentasvir (ABT-530) is a novel and pan-genotypic hepatitis C virus (HCV) NS5A inhibitor with EC50 ranging from 1.4 pM to 5.0 pM against HCV replicons containing NS5A from genotypes 1 to 6. |
| M20529 | Glecaprevir | Glecaprevir is a hepatitis C virus (HCV) nonstructural (NS) protein 3/4A protease inhibitor that targets the the viral RNA replication. It displays IC50 values ranging from 3.5 to 11.3 nM for clinical isolates of HCV genotypes 1a, 1b, 2a, 2b, 3a, 4a, 5a, and 6a. |
| M20479 | Tizoxanide | Tizoxanide, a thiazolide anti-infective, is active against anaerobic bacteria, protozoa, and a range of viruses in cell culture models. Tizoxanide (TIZ) has anti-HIV-1 activities and potent inhibition of both HBV and HCV replication with values EC50 of 0.46μM and 0.15 μM, respectively. |
| M9758 | Merimepodib | Merimepodib, also known as VX-497, is an orally bioavailable IMPDH inhibitor with broad spectrum antiviral activities. |
| M9530 | Inarigivir soproxil | Inarigivir soproxil, also known as SB 9200, is a novel agonist of innate immunity, which shows potent antiviral activity against resistant HCV variants. |
| M8881 | Ombitasvir | Ombitasvir is a potent inhibitor of the hepatitis C virus protein NS5A, with EC50s of 0.82 to 19.3 pM against HCV genotypes 1 to 5 and 366 pM against genotype 6a. |
| M8880 | Paritaprevir | Paritaprevir (ABT-450) is a potent non-structural protein 3/4A (NS3/4A) protease inhibitor with EC50 values of 1 and 0.21 nM for HCV 1a and 1b, respectively. |
| M6191 | Velpatasvir | Velpatasvir is a second-generation NS5A inhibitor that inhibits hepatitis C viral replication through acting on the crucial "membranous web" that facilitates RNA replication. |
| M4691 | Lycorine hydrochloride | Lycorine hydrochloride is a natural alkaloid extracted from Amaryllidaceae (Amaryllidaceae) plants. It is a strong HCV inhibitor and melanoma angiogenesis inhibitor with anti-tumor activity. |
| M3693 | Daclatasvir dihydrochloride | Daclatasvir is a potent hepatitis C virus (HCV) NS5A protein inhibitor with picomolar EC50 value . |
| M3680 | GS-9451 | GS-9451, a novel hepatitis C virus (HCV) nonstructural 3/4a (NS3/4a) protease inhibitor, is highly active in patients infected with HCV genotype 1 (GT 1). |
| M3666 | Sofosbuvir (PSI-7977) | Sofosbuvir (GS-7977) is an HCV RNA replication inhibitor with an EC50 of 92 nM. |
| M3627 | Vaniprevir | Vaniprevir (MK-7009) is a non-covalent competitive inhibitor of the hepatitis C virus (HCV) NS3/4A protease. |
| M3624 | Boceprevir (EBP 520) | Boceprevir (EBP-520, SCH503034) is an HCV protease inhibitor (Ki=14 nM) for the treatment of hepatitis C virus infection. |
| M3512 | VX-222 | VX-222 (VCH-222) is a novel, potent and selective inhibitor of HCV polymerase with IC50 of 0.94-1.2 μM, 15.3-fold less effective for mutant M423T, and 108-fold less effective for mutant I482L. |
| M3278 | MK-5172 (Grazoprevir) | MK-5172 is a novel NS3/4, a protease inhibitor for chronic HCV infection (Enzyme Ki for genotype1b, 2a, 2b and 3a at ＜0.02, 0.15, 0.02 and 0.7 nM, respectively). |
| M2727 | GS-9256 | GS-9256 is a novel phosphinic acid derived inhibitor of the HCV NS3/4A protease with IC50 of 4 nM. |
| M2554 | TMC435350 | TMC435350 is a highly specific and potent inhibitor of NS3/4A protease (Ki = 0.36 nM) and viral replication (replicon EC50 = 7.8 nM). |
| M2553 | GS-5885 | GS-5885 is an inhibitor of the hepatitis C virus (HCV) NS5A protein and exhibits potent suppression of genotype 1 HCV replicons. |
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