| Cat.No. | Name | Information |
|---|---|---|
| M4691 | Lycorine hydrochloride | Lycorine hydrochloride is a natural alkaloid extracted from Amaryllidaceae (Amaryllidaceae) plants. It is a strong HCV inhibitor and melanoma angiogenesis inhibitor with anti-tumor activity. |
| M2333 | Dasabuvir (ABT-333) | ABT-333 is a nonnucleoside NS5B polymerase inhibitor for the treatment of HCV infection. |
| M2349 | (R)-Nepicastat hydrochloride | (R)-Nepicastat hydrochloride, the R-enantiomer of Nepicastat hydrochloride, is a potent and selective inhibitor with IC50 of 25.1 nM and 18.3 nM for bovine and human dopamine-β-hydroxylase, with negligible affinity for twelve other enzymes and thirteen neurotransmitter receptors. |
| M2340 | Asunaprevir | Asunaprevir (BMS-650032) is a novel inhibitor of the hepatitis C virus enzyme serine protease NS3. |
| M2333 | Dasabuvir (ABT-333) | ABT-333 is a nonnucleoside NS5B polymerase inhibitor for the treatment of HCV infection. |
| M2203 | Elbasvir | Elbasvir (MK-8742) is a hepatitis C virus nonstructural protein 5A (HCV NS5A) replication complex inhibitor, with EC50s of 4, 3 and 3 nM against genotype 1a, 1b, and 2a, respectively. |
| M1843 | BMS-790052 | BMS-790052 (Daclatasvir) is a first-in-class, nonstructural protein 5A (NS5A) replication complex inhibitor with an EC50 of 9-50 pM. |
| M1808 | Telaprevir | Telaprevir (VX-950) is a novel hepatitis C virus (HCV) NS3-4A protease inhibitor with IC50 of < 0.2 μM. |
| M55815 | ITMN 4077 | ITMN 4077 is a macrocyclic inhibitor against Hepatitis C Virus (HCV) NS3 protease (EC50: 2131 nM). |
| M53497 | Hepatitis C Virus S5A/5B | Hepatitis C Virus S5A/5B is a synthetic peptide substrate. |
| M53496 | Ac-D-DGla-LI-Cha-C | Ac-D-DGla-LI-Cha-C is a potent HCV protease inhibitor peptide. |
| M53495 | Ac-EEVVAC-pNA | Ac-EEVVAC-pNA is a chromogenic substrate for a continuous spectrophotometric assay of HCV NS3 protease. |
| M53494 | Hepatitis Virus C NS3 Protease Inhibitor 2 | Hepatitis Virus C NS3 Protease Inhibitor 2 is a product-based peptide inhibitor of hepatitis C virus (HCV) NS3 protease, with a Ki of 41 nM. |
| M40946 | Mipomersen | Mipomersen is a 20-base gapmer (antisense oligonucleotide) that inhibits apolipoprotein B (apoB) and lowers LDL, which can be used in studies related to hyperlipidemia. In addition, Mipomersen has anti-HCV activity. |
| M38751 | Isoeuphorbetin | Isoeuphorbetin, a dimeric coumarin isolated from Viola philippica, is a potent HCV protease inhibitor with an IC50 of 3.63 µg/mL. |
| M28398 | Grazoprevir sodium salt | Grazoprevir sodium salt (MK-5172 sodium salt) is a selective inhibitor of Hepatitis C virus NS3/4a protease with broad activity across genotypes and resistant variants, with Kis of 0.01 nM (gt1b), 0.01 nM (gt1a), 0.08 nM (gt2a), 0.15 nM (gt2b), 0.90 nM (gt3a), respectively. Grazoprevir sodium salt inhibits SARS-CoV-2 3CLpro activity. |
| M28219 | Grazoprevir hydrate | Grazoprevir hydrate (MK-5172 hydrate) is a selective inhibitor of Hepatitis C virus NS3/4a protease with broad activity across genotypes and resistant variants, with Kis of 0.01 nM (gt1b), 0.01 nM (gt1a), 0.08 nM (gt2a), 0.15 nM (gt2b), 0.90 nM (gt3a), respectively. Grazoprevir hydrate inhibits SARS-CoV-2 3CLpro activity. |
| M27943 | Grazoprevir potassium salt | Grazoprevir potassium salt (MK-5172 potassium salt) is a selective inhibitor of Hepatitis C virus NS3/4a protease with broad activity across genotypes and resistant variants, with Kis of 0.01 nM (gt1b), 0.01 nM (gt1a), 0.08 nM (gt2a), 0.15 nM (gt2b), 0.90 nM (gt3a), respectively. Grazoprevir potassium salt inhibits SARS-CoV-2 3CLpro activity. |
| M21642 | Voxilaprevir (GS-9857) | Voxilaprevir (GS-9857) is a noncovalent, reversible inhibitor of HCV NS3/4A protease inhibitor (PI) with pangenotypic antiviral activity. Voxilaprevir inhibits genotype 1b and 3a wild-type NS3 proteases with Ki values of 0.038 nM and 0.066 nM, respectively. |
| M21290 | BMS-986144 | BMS-986144 is a third generation pan-genotypic NS3/4A protease inhibitor.BMS-986144 inhibits GT-1a, GT-1b, GT-2a, GT-3a, 1a R155X, 1b D168V replicon with EC50 values of 2.3, 0.7, 1.0, 12, 8.0, 5.8 nM, respectively.BMS-986144 has the potential to study HCV infection. |
| M21285 | AL-611 | AL-611 is an HCV NS5B polymerase inhibitor (EC50 = 5 nM). |
| M21259 | GSK2818713 | GSK2818713 is an HCV NS5A replication complex inhibitor with an interesting biphenyl ligand. |
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