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Mipomersen

Cat. No. M40946

All AbMole products are for research use only, cannot be used for human consumption.

Mipomersen Structure
Synonym:

ISIS 301012

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Quality Control & Documentation
Biological Activity

Mipomersen is a 20-base gapmer (antisense oligonucleotide) that inhibits apolipoprotein B (apoB) and lowers LDL, which can be used in studies related to hyperlipidemia. In addition, Mipomersen has anti-HCV activity.

Chemical Information
Molecular Weight 7177.15
Formula C230H324N67O122P19S19
CAS Number 1000120-98-8
Solubility (25°C) Water 100 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Freddy Duarte Lau et al. JAMA Cardiol. Lipoprotein(a) and its Significance in Cardiovascular Disease: A Review

[2] Diego Chambergo-Michilot et al. Vasc Health Risk Manag. Mipomersen in Familial Hypercholesterolemia: An Update on Health-Related Quality of Life and Patient-Reported Outcomes

[3] Johnathon Seth Parham et al. Expert Opin Pharmacother. Mipomersen and its use in familial hypercholesterolemia

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Keywords: Mipomersen, ISIS 301012 supplier, HCV Protease, inhibitors, activators

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