GSK-3 Glycogen synthase kinase 3

Cat.No.	Name	Information
M1692	CHIR-99021	CHIR-99021 (CT99021) is an aminopyrimidine derivative that inhibits GSK3α and GSK3β with IC50 values of 10 and 6.7 nM, respectively.
M2304	TWS119	TWS119 is a GSK-3β inhibitor with IC50 of 30 nM.
M1989	CHIR-99021 HCl	CHIR-99021 HCl (CT99021) is a hydrochloride of CHIR-99021, with IC50 of 10 nM and 6.7 nM for GSK-3α and GSK-3β, respectively.
M21232	MeBIO	MeBIO, an analog of 6-bromoindirubin-3'-oxime, has been suggested to possess the structural basis for a potent and selective inhibitor of glycogen synthase kinase-3 (GSK3) and cyclin-dependent kinases. MeBIO displays minimal activity against CDK1/Cyclin B, GSK-3, and CDK5/p25 (IC50 values are 92.0, 44-100 and >100 μM respectively). MeBIO is a potent AhR (aryl hydrocarbon receptor) agonist.
M20836	Indirubin-3′-oxime	Indirubin-3′-oxime (IDR3O, I3O) is an indirubin analogue that shows favorable inhibitory activity targeting GSK-3β and CDKs. Indirubin-3′-oxime also inhibits JNKs with IC50s of 0.8 μM, 1.4 μM, and 1.0 μM for JNK1, JNK2, and JNK3, respectively. Indirubin-3′-oxime activates Wnt/β-catenin signaling and inhibits adipocyte differentiation and obesity.
M20731	9-ing-41	9-ING-41 is a potent inhibitor of glycogen synthase kinase-3 (GSK-3) with antitumor activity. 9-ING-41 induces apoptosis and cell cycle arrest at prophase by targeting centrosomes and microtubule-bound GSK3β.
M20489	5-Bromoindole	5-bromoindole is an important pharmaceutical chemical intermediate and a potential inhibitor of glycogen synthase kinase 3 (GSK-3).
M20324	WAY-333184	WAY-333184 is a inhibitor of glycogen synthase kinase-3b (GSK-3b).
M20308	WAY-333175	WAY-333175 is a inhibitor of glycogen synthase kinase-3b (GSK-3b).
M20239	WAY-634931	WAY-634931 is a inhibitor of GSK3 kinases
M20222	WAY-624687	WAY-624687 is a GSK3 inhibitor
M20198	WAY-606957	WAY-606957 is a inhibitor of GSK3 kinases.
M20197	WAY-606956	WAY-606956 is a inhibitor of GSK3 kinases.
M20196	WAY-606954	WAY-606954 is a inhibitor of GSK3 kinases.
M20192	WAY-603610	WAY-603610 is a inhibitor of GSK3 kinases.
M20175	WAY-381785	WAY-381785 is a inhibitor of GSK3 kinases.
M20171	WAY-358024	WAY-358024 is a GSK-3b inhibitor
M20148	WAY-344977	WAY-344977 is a inhibitor of Glycogen Synthase Kinase 3.
M20114	WAY-326578	WAY-326578 has GSK-3b inhibition.
M20098	WAY-322545	WAY-322545 altering the lifespan of a eukaryotic organism
M20045	WAY-271413	WAY-271413 is a GSK-3β inhibitor.
M14839	KY19382	KY19382 is a potent and orally active dual inhibitor of CXXC5-DVL and GSK3β, with IC₅₀s of 19 and 10 nM, respectively.
M14838	GSK-3 inhibitor 1	GSK-3 inhibitor 1 is an inhibitor of GSK-3.

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GSK-3 Glycogen synthase kinase 3

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