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GSK-3 Glycogen synthase kinase 3

Cat.No.  Name Information
M1692 CHIR-99021 CHIR-99021 (CT99021) is an aminopyrimidine derivative that inhibits GSK3α and GSK3β with IC50 values of 10 and 6.7 nM, respectively.
M2304 TWS119 TWS119 is a GSK-3β inhibitor with IC50 of 30 nM.
M1989 CHIR-99021 HCl CHIR-99021 HCl (CT99021) is a hydrochloride of CHIR-99021, with IC50 of 10 nM and 6.7 nM for GSK-3α and GSK-3β, respectively.
M49760 GSK-3β inhibitor 7 GSK-3β inhibitor 7 is a GSK-3β inhibitor with an IC50 value of 5.25 μM.
M49759 GSK-3β inhibitor 6 GSK-3β inhibitor 6 is a potent GSK-3β inhibitor with an IC50 value of 24.4 μM.
M49758 GSK-3β inhibitor 3 GSK-3β inhibitor 3 is a potent, selective, irreversible and covalent inhibitor of Glycogen Synthase Kinase 3β (GSK-3β), with an IC50 of 6.6 μM.
M49756 GSK3-IN-1 GSK3-IN-1 is a GSK-3 inhibitor with an IC50 value of 12 μM.
M49755 Cu(II)GTSM Cu(II)GTSM, a cell-permeable Cu-complex, significantly inhibits GSK3β.
M49754 C-Peptide 1 (rat) C-Peptide 1 (rat), a peptide, is aβ-catenin/GSK-3β activator.
M49753 Cazpaullone Cazpaullone is a glycogen synthase kinase-3 (GSK-3) inhibitor.
M49752 BRD5648 BRD5648 ((R)-BRD0705) is a negative control of BRD0705.
M49751 ARN25068 ARN25068 is a sub-micromolar inhibitor of the three protein kinases, GSK-3β, FYN and DYRK1A to tackle tau hyperphosphorylation.
M49750 5-Iodo-indirubin-3'-monoxime 5-Iodo-indirubin-3'-monoxime is a potent GSK-3β, CDK5/P25 and CDK1/cyclin B inhibitor, competing with ATP for binding to the catalytic site of the kinase, with IC50s of 9, 20 and 25 nM, respectively.
M49749 2B-(SP) (TFA) 2B-(SP) TFA is a eIF2B-based substrate for glycogen synthase kinase-3 (GSK-3).
M49748 2B-(SP) 2B-(SP) is a eIF2B-based substrate for glycogen synthase kinase-3 (GSK-3).
M49747 Lithium chloride hydrate Lithium chloride hydrate, an orally active mood stabilizer, is a potent virus inhibitor and effective immunomodulatory agent.
M49746 GSK3β inhibitor II GSK3β inhibitor II is an inhibitor of GSK3β.
M49745 GSK-3 Inhibitor XIII GSK-3 Inhibitor XIII is a potent and ATP-competitive GSK-3 inhibitor with a Ki of 24 nM.
M49736 hAChE-IN-5 hAChE-IN-5 is a potent hAChE and hBuChE inhibitor with IC50 values of 0.17 μM and 0.17 μM, respectively.
M43382 6-Me-ATP 6-Me-ATP (N6-Methyl-ATP) is a N6-modified ATP derivative.
M43381 PROTAC GSK-3β Degrader-1 PROTAC GSK-3β Degrader-1 is a degrader targets GSK-3β degradation with an IC50 value of 833 nM.
M43380 GSK-3β inhibitor 13 GSK-3β inhibitor 13 is an orally active and potent GSK-3β inhibitor with blood-brain permeability.
M43379 GSK-3 inhibitor 3 GSK-3 inhibitor 3 is a selective, orally active and brain-penetrant inhibitor of GSK-3, with IC50s of 0.35 nM and 0.25 nM for GSK-3α and GSK-3β, respectively.




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