Cat.No. | Name | Information |
---|---|---|
M1692 | CHIR-99021 | CHIR-99021 (CT99021) is an aminopyrimidine derivative that inhibits GSK3α and GSK3β with IC50 values of 10 and 6.7 nM, respectively. |
M2304 | TWS119 | TWS119 is a GSK-3β inhibitor with IC50 of 30 nM. |
M1989 | CHIR-99021 HCl | CHIR-99021 HCl (CT99021) is a hydrochloride of CHIR-99021, with IC50 of 10 nM and 6.7 nM for GSK-3α and GSK-3β, respectively. |
M49760 | GSK-3β inhibitor 7 | GSK-3β inhibitor 7 is a GSK-3β inhibitor with an IC50 value of 5.25 μM. |
M49759 | GSK-3β inhibitor 6 | GSK-3β inhibitor 6 is a potent GSK-3β inhibitor with an IC50 value of 24.4 μM. |
M49758 | GSK-3β inhibitor 3 | GSK-3β inhibitor 3 is a potent, selective, irreversible and covalent inhibitor of Glycogen Synthase Kinase 3β (GSK-3β), with an IC50 of 6.6 μM. |
M49756 | GSK3-IN-1 | GSK3-IN-1 is a GSK-3 inhibitor with an IC50 value of 12 μM. |
M49755 | Cu(II)GTSM | Cu(II)GTSM, a cell-permeable Cu-complex, significantly inhibits GSK3β. |
M49754 | C-Peptide 1 (rat) | C-Peptide 1 (rat), a peptide, is aβ-catenin/GSK-3β activator. |
M49753 | Cazpaullone | Cazpaullone is a glycogen synthase kinase-3 (GSK-3) inhibitor. |
M49752 | BRD5648 | BRD5648 ((R)-BRD0705) is a negative control of BRD0705. |
M49751 | ARN25068 | ARN25068 is a sub-micromolar inhibitor of the three protein kinases, GSK-3β, FYN and DYRK1A to tackle tau hyperphosphorylation. |
M49750 | 5-Iodo-indirubin-3'-monoxime | 5-Iodo-indirubin-3'-monoxime is a potent GSK-3β, CDK5/P25 and CDK1/cyclin B inhibitor, competing with ATP for binding to the catalytic site of the kinase, with IC50s of 9, 20 and 25 nM, respectively. |
M49749 | 2B-(SP) (TFA) | 2B-(SP) TFA is a eIF2B-based substrate for glycogen synthase kinase-3 (GSK-3). |
M49748 | 2B-(SP) | 2B-(SP) is a eIF2B-based substrate for glycogen synthase kinase-3 (GSK-3). |
M49747 | Lithium chloride hydrate | Lithium chloride hydrate, an orally active mood stabilizer, is a potent virus inhibitor and effective immunomodulatory agent. |
M49746 | GSK3β inhibitor II | GSK3β inhibitor II is an inhibitor of GSK3β. |
M49745 | GSK-3 Inhibitor XIII | GSK-3 Inhibitor XIII is a potent and ATP-competitive GSK-3 inhibitor with a Ki of 24 nM. |
M49736 | hAChE-IN-5 | hAChE-IN-5 is a potent hAChE and hBuChE inhibitor with IC50 values of 0.17 μM and 0.17 μM, respectively. |
M43382 | 6-Me-ATP | 6-Me-ATP (N6-Methyl-ATP) is a N6-modified ATP derivative. |
M43381 | PROTAC GSK-3β Degrader-1 | PROTAC GSK-3β Degrader-1 is a degrader targets GSK-3β degradation with an IC50 value of 833 nM. |
M43380 | GSK-3β inhibitor 13 | GSK-3β inhibitor 13 is an orally active and potent GSK-3β inhibitor with blood-brain permeability. |
M43379 | GSK-3 inhibitor 3 | GSK-3 inhibitor 3 is a selective, orally active and brain-penetrant inhibitor of GSK-3, with IC50s of 0.35 nM and 0.25 nM for GSK-3α and GSK-3β, respectively. |
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