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PF-04802367 (PF-367) is a highly selective GSK-3 inhibitor with an IC50 of 2.1 nM based on a recombinant human GSK-3β enzyme assay and 1.1 nM based on ADP-Glo assay. PF-04802367 shows desirable central nervous system (CNS) properties and potency.
| Molecular Weight | 361.78 |
| Formula | C16H16ClN5O3 |
| CAS Number | 1962178-27-3 |
| Form | Solid |
| Solubility (25°C) | DMSO 90 mg/mL (ultrasonic) |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
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