All AbMole products are for research use only, cannot be used for human consumption.
BIO (GSK-3 Inhibitor IX, 6-bromoindirubin-3-oxime, 6-Bromoindirubin-3'-oxime, MLS 2052) is a specific GSK-3 inhibitor, the IC50 acting on GSK-3α/β in cell-free assays is 5 nM, which is more than 16 times more selective than ACTing on CDK5. It is also a pan-JAK inhibitor with an IC50 value of 30 nM for Tyk2. BIO induces apoptosis in human melanoma cells.
Patent. US2024240141A1 2024 Jul 18.
Patent. US2024240141A1
BIO purchased from AbMole
Patent. US2024252687A1 2024 Aug 01.
Patent. US2024252687A1
BIO purchased from AbMole
| Molecular Weight | 356.17 |
| Formula | C16H10BrN3O2 |
| CAS Number | 667463-62-9 |
| Solubility (25°C) | DMSO: >5 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[5] F Oveissi, et al. Materials and manufacturing perspectives in engineering heart valves: a review
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Products are for research use only. Not for human use. We do not sell to patients.
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