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Bikinin is a strong activator of brassinosteroid (BR) signaling. It is an Arabidopsis GSK-3 Inhibitor, an Arabidopsis SHAGGY-related Kinase Inhibitor, and a GSK-3-like Kinase BIN2 Inhibitor. Bikinin directly inhibits BIN2 (group II GSK3s) by interfering with ATP binding. Bikinin is specific toward a subset of Arabidopsis GSK3 kinases including BIN2 and ASK α, γ, ε, ι, and θ.
Molecular Weight | 273.08 |
Formula | C9H9BrN2O3 |
CAS Number | 188011-69-0 |
Solubility (25°C) | DMSO ≥ 30 mg/mL |
Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[1] Wilfried Rozhon, et al. Inhibitors of Brassinosteroid Biosynthesis and Signal Transduction
[2] Takema Sasaki, et al. Imaging of Developing Metaxylem Vessel Elements in Cultured Hypocotyls
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