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Metabolite/Endogenous Metabolite Metabolite/Endogenous Metabolite

Inhibitor

Cat.No.  Name Information
M10346 Glutamic acid (L-Glutamic acid) L-Glutamic acid acts as an excitatory transmitter and an agonist at all subtypes of glutamate receptors (metabotropic, kainate, NMDA, and AMPA).
M18309 p-Hydroxy-cinnamic acid p-Hydroxy-cinnamic acid inhibits platelet activity, with IC50s of 371 μM, 126 μM for thromboxane B2 production and lipopolysaccharide-induced prostaglandin E2 generation, respectively.
M6687 Docosahexaenoic acid (Oil) Docosahexaenoic Acid (DHA) is an omega-3 fatty acid abundantly present brain and retina. Docosahexaenoic acid is a RXR agonist.
M9953 Taurocholic acid Taurocholic acid (N-Choloyltaurine) is a bile acid, which can be used in the emulsification of fats.
M10168 L-Lactic acid L-Lactic acid is an organic acid, which can be used as a precursor for the production of the bioplastic polymer poly-lactic acid.
M5786 Metyrapone Metyrapone (Metapirone) is a potent and orally active 11β-hydroxylase inhibitor and an autophagy activator, also inhibits the production of aldosterone. Metyrapone (Metapirone) inhibits cytochrome P450-mediated ω/ω-1 hydroxylase activity and CYP11B1.
M5782 Methylcobalamin Methylcobalamin a cobalamin, is a form of vitamin B12.
M5758 L-Thyroxine L-Thyroxine is a synthetic form of thyroxine and a hormone replacement compound.
M5757 L-SelenoMethionine L-SelenoMethionine is a major natural food-form of selenium.
M5753 L-Ornithine L-ornithine has an antifatigue effect by increasing the efficiency of energy consumption and promoting the excretion of ammonia. It is one of the key reactants in the urea cycle.
M5725 Lactulose Lactulose, a disaccharide composed of galactose and fructose, is a stimulator of health-promoting bacterium growth in the gastrointestinal tract.
M5681 Gluconate Calcium Calcium gluconate is a mineral supplement, manufactured by the neutralization of gluconic acid with lime or calcium carbonate.
M5450 Benzyl alcohol Benzyl alcohol is an inhibitor of P450 enzyme. Benzyl alcohol mediated Toll-Like Receptor 4 to reduce the inflammatory response of liver injury in mice. Benzyl alcohol is used as a local anesthetic. Also, it is used in the manufacture of other benzyl compounds, as a pharmaceutic aid, and in perfumery and flavoring.
M5436 Azelaic acid Azelaic acid is an unsaturated fatty acid derived from plant seeds, which can also be derived from ozonolysis of oleic acid, and has antimicrobial and antioxidant activity.
M5388 Ademetionine Ademetionine (S-adenosyl-l-methionine; SAMe) is a naturally-occurring substance which is a major source of methyl groups in the brain.
M5370 5,5-Dimethyloxazolidine-2,4-dione Dimethadione is an anticonvulsant that is the active metabolite of trimethadione.
M5362 3-Methylsalicylic acid 3-Methylsalicylic acid is a salicylic acid derivative that acts on human plasma and has significant fibrinolytic activity by activating the fibrinolytic system.
M5066 N-Desethyl Sunitinib N-desethyl sunitinib is a major and pharmacologically active metabolite of sunitinib, which is potent, ATP-competitive VEGFR, PDGFRβ and KIT inhibitor (Ki values are 2, 9, 17, 8 and 4 nM for VEGFR -1, -2, -3, PDGFRβ and KIT respectively).
M4943 3,4,5-Trimethoxyphenylacetic acid Cell suspensions did not release carbon dioxide from 3,4-[methoxyl-14C]dihydroxy-5-methoxyphenylacetate but accumulated 1 mol of methanol per mol of 3,4,5-trimethoxyphenylacetate oxidized.
M4842 Cotinine Cotinine is an alkaloid found in tobacco and is also the predominant metabolite of nicotine.
M4781 Homovanillic-acid Homovanillic acid is a dopamine metabolite associated with aromatic amino acid decarboxylase deficiency, celiac disease, growth hormone deficiency, and adiponectin reductase deficiency.
M4770 Berberrubine chloride Berberrubine chloride is an active metabolite of berberine, attenuates ulcerative colitis in mice model.
M4732 Palmitic acid Palmitic acid is a long-chain saturated fatty acid commonly found in both animals and plants. Palmitic acid (PA) can induce the expression of glucose-regulated protein 78 (GRP78) and CCAAT/enhancer binding protein homologous protein (CHOP) in in mouse granulosa cells. Palmitic acid can be used to establish a cell steatosis model.
M4730 Diosbulbin-B Diosbulbin B is derived from D. Bulbifera L. Diterpene lactone isolated from the diterpene lactone has antitumor activity. Diosbulbin B can cause liver injury.
M4729 α-Cyperone Alpha-cyperone (α -cyperone) is associated with down-regulated expression of COX-2, IL-6, NCK-2, Cdc42, and Rac1, thereby reducing the inflammatory response.*The compound is unstable in solutions, freshly prepared is recommended




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