Free shipping on all orders over $ 500

(Z)-Aconitic acid

Cat. No. M11218
(Z)-Aconitic acid Structure
Synonym:

1,2,3-PROPENETRICARBOXYLIC ACID

Size Price Availability Quantity
25mg USD 95  USD95 In stock
Free Delivery on orders over USD 500 Bulk Inquiry?
Quality Control & Documentation
Biological Activity

(Z)-Aconitic acid (cis-Aconitic acid) is a cis isomer of Aconitic acid. (Z)-Aconitic acid (cis-Aconitic acid) is an intermediate product of the isomerization of citrate into isocicirate in the tricarboxylic acid cycle.

Chemical Information
Molecular Weight 174.11
Formula C6H6O6
CAS Number 585-84-2
Solubility (25°C) DMSO ≥ 60 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Conversion of different model animals based on BSA (PMID: 27057123)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.

References

[1] Billy T Tchegnitegni, et al. Z Naturforsch C J Biosci. A dihydrochalcone derivative and further steroidal saponins from Sansevieria trifasciata Prain

[2] Qing Huang, et al. Yao Xue Xue Bao. [Metabonomic profiling of plasma metabolites in Wistar rats to study the effect of aging by means of GC/TOFMS-based techniques]

[3] Chul-Sa Kim, et al. Z Naturforsch C J Biosci. Antifeedants of Indian barnyard millet, Echinochloa frumentacea link, against brown planthopper, Nilaparvata lugens (Stål)

[4] Bernd Schwarz, et al. J Agric Food Chem. Isolation, structure determination, and sensory activity of mouth-drying and astringent nitrogen-containing phytochemicals isolated from red currants (Ribes rubrum)

[5] I Ruhl, et al. Z Lebensm Unters Forsch. [Organic acids in vegetables. I. Brassica, leaf and bulb vegetables as well as carrots and celery]

Related Metabolite/Endogenous Metabolite Products
D-Thyroxine

D-Thyroxine is a thyroid hormone that can inhibit TSH secretion. D-Thyroxine can be used for the research of hypercholesterolemia.
Allolithocholic acid

Allolithocholic acid is a steroid acid could found in normal serum and feces. Allolithocholic acid facilitates excretion, absorption, and transport of fats and sterols in the intestine and liver.
Biliverdin

Biliverdin is the product of the oxidation of bilirubin. Biliverdin can be synthesized via a non-protoporphyrin pathway in Corynebacterium glutamicum.
Stachyose hydrate

Stachyose tetrahydrate is a functional oligosaccharide, acts as a prebiotic. Stachyose tetrahydrate can prevent indirectly colon cancer cell growth by promoting the proliferation of probiotics or producing beneficial materials in the intestine. Stachyose hydrate exhibit a hypoglycemic effect, and improve inflammation through modulating gut microbiota.
Stachyose tetrahydrate

Stachyose tetrahydrate is a functional oligosaccharide, acts as a prebiotic. Stachyose tetrahydrate can prevent indirectly colon cancer cell growth by promoting the proliferation of probiotics or producing beneficial materials in the intestine.
  Catalog
Abmole Inhibitor Catalog




Keywords: (Z)-Aconitic acid, 1,2,3-PROPENETRICARBOXYLIC ACID supplier, Metabolite/Endogenous Metabolite, inhibitors, activators

 
Get to Know Us
Customer Support
Resources
Contact Us

Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2023 AbMole BioScience. All Rights Reserved.