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L-Lactic acid

Cat. No. M10168
L-Lactic acid Structure
Size Price Availability Quantity
1G USD 75  USD75 In stock
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Quality Control
  • Current batch:
  • Purity >98.5%
  • COA
  • MSDS
Biological Activity

L-Lactic acid is an organic acid, which can be used as a precursor for the production of the bioplastic polymer poly-lactic acid.

Conversion of different model animals based on BSA (Value based on data from FDA Draft Guidelines)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.

Chemical Information
Molecular Weight 90.08
Formula C3H6O3
CAS Number 79-33-4
Purity >98.5%
Solubility DMSO 90 mg/mL
Storage 2-8°C, dry, sealed
References

[1] Miroslav Pohanka. Biomed Res Int. D-Lactic Acid as a Metabolite: Toxicology, Diagnosis, and Detection

[2] Andrew Breithaupt, et al. Facial Plast Surg Clin North Am. Collagen Stimulators: Poly-L-Lactic Acid and Calcium Hydroxyl Apatite

[3] Veeresh Juturu, et al. Crit Rev Biotechnol. Microbial production of lactic acid: the latest development

[4] Sanjay P Keni, et al. Facial Plast Surg Clin North Am. Sculptra (injectable poly-L-lactic acid)

[5] Caroline M Perry. Am J Clin Dermatol. Poly-L-lactic acid

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