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Hypoxanthine

Cat. No. M10639

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Hypoxanthine Structure
Synonym:

purine-6(1H)-one; 6-Hydroxypurine; Purin-6-ol; Sarcine

Size Price Availability Quantity
50mg USD 40  USD40 In stock
100mg USD 60  USD60 In stock
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Quality Control & Documentation
Biological Activity

Hypoxanthine (6-Hydroxypurine) is a potential free radical generator and could be used as an indicator of hypoxia. 6-Hydroxypurine seems to play a role in posthypoxic reoxygenation cell injury through oxygen radical production and is therefore involved in the pathogenesis of a number of diseases. 6-Hydroxypurine also modulates a number of other processes because it reacts with benzodiazepine receptors and inhibits phosphodiesterase in the brain.

Chemical Information
Molecular Weight 136.11
Formula C5H4N4O
CAS Number 68-94-0
Solubility (25°C) DMSO 8 mg/mL
1 M NaOH: 25 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Shuming Zhang, et al. Biochimie. Epigenetically modified N 6-methyladenine inhibits DNA replication by human DNA polymerase iota

[2] Yasuhiro Oba, et al. Nat Commun. Nucleobase synthesis in interstellar ices

[3] Yogaraje Gowda C Varadaiah, et al. Arch Physiol Biochem. Purine metabolites can indicate diabetes progression

[4] Hui Ding, et al. Yi Chuan. [Research progress in hypoxanthine-guanine phosphoribosyltrans-ferase]

[5] S TRICERRI, et al. Farmaco Sci. [Quantitative spectrophotometric determination of 6-hydroxypurine in the presence of 2, 6-dihydroxypurine]

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Urolithin M7

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Keywords: Hypoxanthine, purine-6(1H)-one; 6-Hydroxypurine; Purin-6-ol; Sarcine supplier, Metabolite/Endogenous Metabolite, inhibitors, activators

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