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Hypoxanthine (6-Hydroxypurine) is a potential free radical generator and could be used as an indicator of hypoxia. 6-Hydroxypurine seems to play a role in posthypoxic reoxygenation cell injury through oxygen radical production and is therefore involved in the pathogenesis of a number of diseases. 6-Hydroxypurine also modulates a number of other processes because it reacts with benzodiazepine receptors and inhibits phosphodiesterase in the brain.
| Molecular Weight | 136.11 |
| Formula | C5H4N4O |
| CAS Number | 68-94-0 |
| Solubility (25°C) | DMSO 8 mg/mL 1 M NaOH: 25 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[2] Yasuhiro Oba, et al. Nat Commun. Nucleobase synthesis in interstellar ices
| Related Metabolite/Endogenous Metabolite Products |
|---|
| p-Cresol glucuronide
p-Cresol glucuronide is a metabolite of p-cresol, it is a prototype protein-bound uremic toxin. |
| Oleamide
Oleamide is an endogenous fatty acid amide. |
| Deoxycarnitine chloride
Deoxycarnitine chloride is angiopathic substance produced as an intermediary metabolite by gut microbiota. |
| Monobutyl phthalate
Monobutyl phthalate, a major metabolite of dibutyl phthalate (DBP), possesses antiandrogenic effects. Monobutyl phthalate is an embryotoxicant. |
| Testosterone sulfate (pyridinium)
Testosterone sulfate pyridinium is a Testosterone sulfate with a pyridinium. Testosterone sulfate is the metabolite of Testosterone. |
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